neurotrophic tyrosine kinase, receptor, type 3

詳細情報を見る

同義遺伝子名

Ntrk3, neurotrophic tyrosine kinase, receptor, type 3, AW125844, TrkC

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:23.80
GeneChip 大脳:9 小脳:9.09 脳幹:- 脳梁:- 松果体:- 末梢神経:8.70 脊柱:9.07 網膜:5.68 目:5.81 動脈:- 静脈:6.38 リンパ節:5.76 末梢血:- 脾臓:5.42 胸腺:- 骨髄:5.59 脂肪:7.64 骨:5.55 皮膚:5.72
CAGE 大脳:5.41 小脳:- 脳幹:4.16 脳梁:- 松果体:- 末梢神経:- 脊柱:4.07 網膜:- 目:- 動脈:5.84 静脈:- リンパ節:1.69 末梢血:- 脾臓:0.93 胸腺:2.03 骨髄:- 脂肪:- 骨:0 皮膚:3.31
RNA-seq 大脳:4.30 小脳:4.30 脳幹:4.30 脳梁:4.30 松果体:4.30 末梢神経:4.30 脊柱:4.30 網膜:4.30 目:4.30 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:29.60 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:35.20     肝臓:-        肺:50.20    膀胱:66.20 腎臓:- 下垂体:25.80 甲状腺:- 副腎:- 膵臓:9.40 乳腺:- 唾液腺:-
GeneChip 子宮:5.73 胎盤:5.78 前立腺:5.77 卵巣:6.15 精巣:5.96 心臓:6.24 骨格筋:6.15 食道:- 胃:5.68 腸:5.57 結腸:- 肝臓:6.25 肺:5.58 膀胱:5.71 腎臓:5.85 下垂体:8.61 甲状腺:- 副腎:7.13 膵臓:6.08 乳腺:6.80 唾液腺:6.22
CAGE 子宮:1.81 胎盤:0.25 前立腺:2.21 卵巣:2.53 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:1.57 腸:1.22 結腸:0.57     肝臓:0.26    肺:1.66 膀胱:2.00 腎臓:- 下垂体:3.42 甲状腺:- 副腎:2.62 膵臓:0.84 乳腺:3.60 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_008746
Gene ID 18213
Unigene ID Mm.334969
Probe set ID 1422329_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000059146

オーソログ対応遺伝子

ヒト[22]  NM_001007156, NM_001012338, NM_001243101, NM_002530
ラット[1]  NM_019248, NM_001012338, NM_001243101, NM_002530

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1327010
1751544
7588071
7605908
7712171
7991545
8114702
8145824
8223273
8283230
8530078
8575307
8764654
8815902
8841198
8889548
8898237
8918886
8955272
9214629
9217002
9232598
9331334
9354331
9364058
9405689
9421165
9472042
9579688
9640332
9699730
9728914
9731539
9736654
9802700
9880597
9881298
10207144
10349636
10357931
10383116
10384880
10398684
10414984
10469347
10491653
10588868
10619477
10674466
10842362
10850491
10854035
11042159
11076861
11114734
11152640
11160433
11217851
11295244
11322334
11356021
11395003
11466433
11487640
11493560
11498051
11684666
11877382
11988169
12021070
12062038
12093746
12117822
12122447
12352981
12388556
12466851
12477932
12495620
12532410
12732177
12774239
12787506
12810600
12941481
14507777
14550777
14568546
14614136
14614961
14622193
14648839
14668342
14681479
14706643
15140017
15247919
15322547
15376326
15497153
15530548
15550985
15558783
15561438
15726425
15820690
15836427
16037097
16141072
16141073
16142215
16183241
16183868
16368089
16446142
16510500
16602821
16673387
16963267
17007838
17101216
17116257
17190606
17254333
17396120
17442456
17543035
17584746
17967808
17991742
18203754
18287559
18385258
18438927
18498732
18498735
18719589
18752272
18848646
19029029
19291307
19322198
19361496
19421194
19610111
19631204
19698958
19838179
19936227
20034568
20064391
20064392
20096094
20133677
20213756
20436479
20457670
20534675
20565848
20574020
20626560
20692345
20811452
20844136
21117150
21262467
21267068
21300867
21364975
21510873
21529369
21543603
21562748
21681751
21734270
21791286
21795538
21804605
21945863
21957238
22048155
22103411
22235033
22253804
22318233
22326227
22345400
22514301
22586713
22903063
22906231
22980123
23029089
23136392
23382219
23393595
23418536
23426664
23516305
23522042
23591430
23648511
23652629
23701859
23792428
23798677
23954828
24027274
24034695
24048855
24173031
24198358
24210822

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0032148  activation of protein kinase B activity
GO:0032856  activation of Ras GTPase activity
GO:0030154  cell differentiation
GO:0042490  mechanoreceptor differentiation
GO:0007275  multicellular organismal development
GO:0048712  negative regulation of astrocyte differentiation
GO:0060548  negative regulation of cell death
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0007399  nervous system development
GO:0048665  neuron fate specification
GO:0001764  neuron migration
GO:0016310  phosphorylation
GO:0048691  positive regulation of axon extension involved in regeneration
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0010628  positive regulation of gene expression
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0050927  positive regulation of positive chemotaxis
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0046875  ephrin receptor binding
GO:0016301  kinase activity
GO:0005030  neurotrophin receptor activity
GO:0000166  nucleotide binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0004714  transmembrane receptor protein tyrosine kinase activity