purinergic receptor P2X, ligand-gated ion channel, 7

詳細情報を見る

同義遺伝子名

P2Z receptor, AI467586, P2rx7, P2X purinoceptor 7, P2x7, P2X7, P2X7 receptor

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:5.20

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:19.10

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:140.40

末梢血:28.80

脾臓:13.20

胸腺:59.30

骨髄:-

脂肪:-

骨:-

皮膚:7.90

GeneChip

大脳:4.84

小脳:5.09

脳幹:-

脳梁:-

松果体:-

末梢神経:5.13

脊柱:5.23

網膜:5.02

目:5.51

動脈:-

静脈:4.92

リンパ節:5.07

末梢血:-

脾臓:5.32

胸腺:-

骨髄:4.91

脂肪:5.11

骨:4.82

皮膚:4.87

CAGE

大脳:2.36

小脳:-

脳幹:2.53

脳梁:-

松果体:-

末梢神経:-

脊柱:2.83

網膜:-

目:-

動脈:2.71

静脈:-

リンパ節:3.46

末梢血:-

脾臓:2.61

胸腺:2.15

骨髄:-

脂肪:-

骨:2.09

皮膚:3.03

RNA-seq

大脳:1.32

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:43.60

胎盤:-

前立腺:-

卵巣:-

精巣:7.40

心臓:18.60

骨格筋:-

食道:-

胃:-

腸:-

結腸:17.60

肝臓:-

肺:20.10

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:45.70

唾液腺:-

GeneChip

子宮:5.81

胎盤:4.97

前立腺:5.22

卵巣:5.19

精巣:5.67

心臓:5.39

骨格筋:5.07

食道:-

胃:5.01

腸:4.86

結腸:-

肝臓:4.94

肺:4.96

膀胱:5.10

腎臓:4.90

下垂体:4.67

甲状腺:-

副腎:4.74

膵臓:5.78

乳腺:5.34

唾液腺:5.21

CAGE

子宮:3.58

胎盤:1.00

前立腺:3.34

卵巣:3.01

精巣:0.99

心臓:-

骨格筋:-

食道:-

胃:2.04

腸:1.84

結腸:2.55

肝臓:1.85

肺:3.26

膀胱:2.98

腎臓:-

下垂体:1.40

甲状腺:-

副腎:2.23

膵臓:1.30

乳腺:2.86

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.21

食道:-

胃:-

腸:-

結腸:-

肝臓:1.36

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_011027
Gene ID	18439
Unigene ID	Mm.42026
Probe set ID	1422218_at [Mouse430_2]
Ensembl ID	ENSMUSG00000029468

オーソログ対応遺伝子

ヒト[1]	NM_002562
ラット [0]

染色体

5F [123,093,920 - 123,141,441]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001429	P2X purinoreceptor
IPR003050	P2X7 purinoceptor

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0032060	bleb formation
GO:0006816	calcium ion transport
GO:0006812	cation transport
GO:0008219	cell death
GO:0000902	cell morphogenesis
GO:0007166	cell surface receptor linked signal transduction
GO:0006884	cell volume homeostasis
GO:0031668	cellular response to extracellular stimulus
GO:0046513	ceramide biosynthetic process
GO:0032963	collagen metabolic process
GO:0019835	cytolysis
GO:0050830	defense response to Gram-positive bacterium
GO:0010467	gene expression
GO:0048873	homeostasis of number of cells within a tissue
GO:0006954	inflammatory response
GO:0034220	ion transmembrane transport
GO:0006811	ion transport
GO:0006900	membrane budding
GO:0051899	membrane depolarization
GO:0006509	membrane protein ectodomain proteolysis
GO:0007005	mitochondrion organization
GO:0044254	multicellular organismal protein catabolic process
GO:0043132	NAD transport
GO:0045779	negative regulation of bone resorption
GO:0043409	negative regulation of MAPKKK cascade
GO:0001845	phagolysosome formation
GO:0006649	phospholipid transfer to membrane
GO:0045332	phospholipid translocation
GO:0007009	plasma membrane organization
GO:0046931	pore complex assembly
GO:0043065	positive regulation of apoptosis
GO:0030501	positive regulation of bone mineralization
GO:0010524	positive regulation of calcium ion transport into cytosol
GO:0043085	positive regulation of catalytic activity
GO:0050715	positive regulation of cytokine secretion
GO:0045919	positive regulation of cytolysis
GO:0051495	positive regulation of cytoskeleton organization
GO:0014054	positive regulation of gamma-aminobutyric acid secretion
GO:0014049	positive regulation of glutamate secretion
GO:0050717	positive regulation of interleukin-1 alpha secretion
GO:0032731	positive regulation of interleukin-1 beta production
GO:0050718	positive regulation of interleukin-1 beta secretion
GO:0032755	positive regulation of interleukin-6 production
GO:0070230	positive regulation of lymphocyte apoptosis
GO:0043410	positive regulation of MAPKKK cascade
GO:0051901	positive regulation of mitochondrial depolarization
GO:0045778	positive regulation of ossification
GO:0032308	positive regulation of prostaglandin secretion
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0050714	positive regulation of protein secretion
GO:0001916	positive regulation of T cell mediated cytotoxicity
GO:0006468	protein amino acid phosphorylation
GO:0051259	protein oligomerization
GO:0016485	protein processing
GO:0019228	regulation of action potential in neuron
GO:0002028	regulation of sodium ion transport
GO:0051209	release of sequestered calcium ion into cytosol
GO:0033198	response to ATP
GO:0009617	response to bacterium
GO:0051592	response to calcium ion
GO:0042493	response to drug
GO:0051602	response to electrical stimulus
GO:0034405	response to fluid shear stress
GO:0032496	response to lipopolysaccharide
GO:0009612	response to mechanical stimulus
GO:0014070	response to organic cyclic substance
GO:0010033	response to organic substance
GO:0010043	response to zinc ion
GO:0019233	sensory perception of pain
GO:0048705	skeletal system morphogenesis
GO:0016079	synaptic vesicle exocytosis
GO:0043029	T cell homeostasis
GO:0042098	T cell proliferation
GO:0055085	transmembrane transport
GO:0006810	transport

Cellular Component

GO:0032059	bleb
GO:0043025	cell soma
GO:0005911	cell-cell junction
GO:0005737	cytoplasm
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0005639	integral to nuclear inner membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0045121	membrane raft
GO:0031594	neuromuscular junction
GO:0043005	neuron projection
GO:0005886	plasma membrane
GO:0043234	protein complex
GO:0045202	synapse
GO:0043195	terminal button

Molecular Function

GO:0005524	ATP binding
GO:0004931	ATP-gated cation channel activity
GO:0015267	channel activity
GO:0005507	copper ion binding
GO:0005216	ion channel activity
GO:0001530	lipopolysaccharide binding
GO:0000287	magnesium ion binding
GO:0005515	protein binding
GO:0043539	protein serine/threonine kinase activator activity
GO:0001614	purinergic nucleotide receptor activity
GO:0004872	receptor activity
GO:0005102	receptor binding
GO:0008270	zinc ion binding

purinergic receptor P2X, ligand-gated ion channel, 7

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function