p21 protein (Cdc42/Rac)-activated kinase 1

詳細情報を見る

同義遺伝子名

PAK-1, Paka, AW045634, Alpha-PAK, p21 (CDKN1A)-activated kinase 1, Pak1, Serine/threonine-protein kinase PAK 1, P65-PAK, p21-activated kinase 1, CDC42/RAC effector kinase PAK-A

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:118.10 小脳:73.70 脳幹:63.60 脳梁:- 松果体:- 末梢神経:- 脊柱:94.60 網膜:- 目:53.20 動脈:168.80 静脈:- リンパ節:- 末梢血:14.40 脾臓:- 胸腺:29.60 骨髄:12.80 脂肪:- 骨:25 皮膚:7.90
GeneChip 大脳:10.84 小脳:11.43 脳幹:- 脳梁:- 松果体:- 末梢神経:9.21 脊柱:11.19 網膜:6.87 目:6.89 動脈:- 静脈:7.36 リンパ節:7.41 末梢血:- 脾臓:7.40 胸腺:- 骨髄:7.45 脂肪:6.47 骨:7.68 皮膚:7.49
CAGE 大脳:5.60 小脳:- 脳幹:5.60 脳梁:- 松果体:- 末梢神経:- 脊柱:5.69 網膜:- 目:- 動脈:1.70 静脈:- リンパ節:3.77 末梢血:- 脾臓:2.89 胸腺:3.13 骨髄:- 脂肪:- 骨:3.54 皮膚:3.65
RNA-seq 大脳:54.25 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:27.60 前立腺:- 卵巣:80.40 精巣:7.40 心臓:- 骨格筋:177.50 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:32.20 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:26.10 唾液腺:-
GeneChip 子宮:7.59 胎盤:7.27 前立腺:6.92 卵巣:6.43 精巣:6.24 心臓:6 骨格筋:8.39 食道:- 胃:8.17 腸:8.91 結腸:- 肝臓:5.76 肺:6.97 膀胱:7.21 腎臓:8.48 下垂体:9.25 甲状腺:- 副腎:7.07 膵臓:7.64 乳腺:7.37 唾液腺:6.71
CAGE 子宮:3.28 胎盤:2.58 前立腺:3.90 卵巣:2.63 精巣:3.03 心臓:- 骨格筋:- 食道:- 胃:3.51 腸:3.64 結腸:4.12     肝臓:2.26    肺:2.95 膀胱:3.12 腎臓:- 下垂体:4.25 甲状腺:- 副腎:3.28 膵臓:2.03 乳腺:2.69 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:4.77 食道:- 胃:- 腸:- 結腸:-     肝臓:1.50        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_011035
Gene ID 18479
Unigene ID Mm.260227
Probe set ID 1420980_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030774

オーソログ対応遺伝子

ヒト[2]  NM_001128620, NM_002576
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0031532  actin cytoskeleton reorganization
GO:0006915  apoptosis
GO:0048754  branching morphogenesis of a tube
GO:0032869  cellular response to insulin stimulus
GO:0033554  cellular response to stress
GO:0016358  dendrite development
GO:0006887  exocytosis
GO:0008152  metabolic process
GO:0060244  negative regulation of cell proliferation involved in contact inhibition
GO:0007528  neuromuscular junction development
GO:0048812  neuron projection morphogenesis
GO:0016310  phosphorylation
GO:0033148  positive regulation of estrogen receptor signaling pathway
GO:0043507  positive regulation of JUN kinase activity
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0051496  positive regulation of stress fiber formation
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0043113  receptor clustering
GO:0032956  regulation of actin cytoskeleton organization
GO:0001666  response to hypoxia
GO:0010033  response to organic substance
GO:0042060  wound healing

Cellular Component

GO:0030424  axon
GO:0030054  cell junction
GO:0005911  cell-cell junction
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030425  dendrite
GO:0005925  focal adhesion
GO:0005794  Golgi apparatus
GO:0030426  growth cone
GO:0014704  intercalated disc
GO:0016020  membrane
GO:0031965  nuclear membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0043234  protein complex
GO:0001726  ruffle
GO:0030018  Z disc

Molecular Function

GO:0005524  ATP binding
GO:0003824  catalytic activity
GO:0005518  collagen binding
GO:0042802  identical protein binding
GO:0016301  kinase activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0004674  protein serine/threonine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups