paired box gene 2

 詳細情報を見る

同義遺伝子名

Pax-2, Pax2, paired box gene 2, Paired box protein Pax-2

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST nodata
GeneChip nodata
CAGE 大脳:0.13 小脳:- 脳幹:0.25 脳梁:- 松果体:- 末梢神経:- 脊柱:1.23 網膜:- 目:- 動脈:0 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:0 骨髄:- 脂肪:- 骨:0 皮膚:0
RNA-seq 大脳:1.48 小脳:1.48 脳幹:1.48 脳梁:1.48 松果体:1.48 末梢神経:1.48 脊柱:1.48 網膜:1.48 目:1.48 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST nodata
GeneChip nodata
CAGE 子宮:2.48 胎盤:0.35 前立腺:0.51 卵巣:1.19 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0 結腸:0     肝臓:0    肺:0 膀胱:0 腎臓:- 下垂体:0 甲状腺:- 副腎:0 膵臓:0 乳腺:0 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_011037
Gene ID 18504
Unigene ID -
Probe set ID -
Ensembl ID ENSMUSG00000004231

オーソログ対応遺伝子

ヒト[10]  NM_000278, NM_003987, NM_003988, NM_003989, NM_003990
ラット[1]  NM_001106361, NM_003987, NM_003988, NM_003989, NM_003990

染色体

19C3  [44,830,539  -  44,912,758]

遺伝子ファミリー (Interpro ID)

IPR001523  Paired box protein, N-terminal
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

1283313
1311084
1457381
1485966
1516825
1679743
1685142
1723950
1974085
1977574
1977575
7558004
7577673
7590254
7590255
7720589
7795640
7835879
7883790
7981748
7990960
8099544
8126546
8163557
8187639
8383297
8395349
8413205
8431641
8482415
8517925
8541222
8575294
8575306
8625814
8626038
8631154
8666231
8666395
8794051
8837770
8943028
8951055
8970821
9054500
9112988
9144207
9152004
9159136
9165114
9226455
9256466
9271117
9297966
9315901
9331350
9342056
9389661
9405645
9409667
9439670
9449663
9449667
9473325
9486536
9501086
9503020
9636075
9637690
9697851
9811592
9853969
9858722
9883582
9895322
10021334
10051411
10101119
10197584
10322633
10328847
10354469
10357934
10373304
10409504
10466411
10471511
10490025
10512984
10536059
10536237
10572052
10587573
10601035
10601036
10625539
10627821
10654602
10662641
10668924
10694420
10749566
10864459
10864462
10908331
10934015
10934027
10934262
10960791
10980123
11003833
11095635
11133159
11171333
11298452
11356033
11472854
11493524
11493536
11493561
11500373
11509181
11511678
11528388
11562352
11688560
11693299
11704761
11731455
11731459
11744391
11748135
11748138
11793341
11804780
11807024
11830579
11839813
11877374
11929848
11959834
11969263
12015298
12050119
12062038
12117823
12130660
12141441
12142028
12167401
12194867
12200151
12231626
12351699
12435353
12435361
12435636
12477932
12482961
12591246
12619136
12631064
12642503
12682014
12729564
12736208
12756174
12756179
12756228
12783782
12783789
12809690
12810586
12832534
12874121
12913075
12915318
14517998
14561758
14585979
14595835
14603255
14610273
14623822
14628042
14651936
14681479
14695375
14695376
14724392
14960494
15003631
15012626
15053978
15064766
15081372
15083520
15084464
15105372
15105374
15121182
15130495
15134635
15153556
15196959
15201220
15201225
15207855
15229182
15242798
15329890
15342483
15363417
15366017
15371513
15376323
15385160
15447689
15469980
15496443
15499560
15520281
15558474
15561999
15580630
15618518
15623552
15634693
15652707
15703187
15741321
15769945
15788454
15789444
15829518
15855632
15872002
15872005
15901662
15905075
15905411
15930101
15930111
15961523
16018995
16038893
16049112
16054034
16203745
16207763
16216236
16223478
16234809
16284942
16287848
16291795
16303964
16319112
16319116
16342201
16368682
16368932
16396903
16412416
16442091
16452098
16458284
16525473
16530751
16540585
16571633
16574431
16597514
16602821
16609680
16631587
16672320
16675530
16682261
16690754
16715081
16735463
16790474
16854970
16900517
16903854
16916509
16942767
16957075
16957084
16979153
16985513
17026983
17035289
17036046
17047028
17079272
17082250
17084361
17107998
17123502
17150206
17150208
17164400
17166916
17166926
17172448
17173889
17196957
17205580
17219401
17229764
17251353
17300925
17314325
17357786
17360405
17360769
17366625
17435047
17470285
17475798
17492640
17537792
17538188
17553904
17589504
17592132
17601531
17609112
17615577
17664423
17785448
17826763
17828260
17855431
17881463
17925232
18083586
18178801
18198335
18287559
18377888
18385072
18395837
18400903
18462697
18480159
18485340
18489003
18495817
18498101
18507827
18521186
18522499
18522874
18539269
18607644
18625210
18634777
18650339
18700968
18721803
18776146
18787044
18829970
18835385
18929642
18930042
18985738
19029045
19037705
19048125
19088088
19093031
19103193
19141316
19150487
19154717
19161241
19217896
19265685
19273906
19327148
19378250
19389377
19463901
19476657
19505455
19540218
19542352
19554387
19581823
19591821
19596317
19619645
19633665
19641016
19715689
19716816
19743445
19754878
19793891
19797899
19809516
19820125
19829382
19854269
19898483
19906857
19914233
19914235
19924827
20004188
20017165
20040500
20081190
20144606
20147377
20150232
20152829
20171952
20181585
20221250
20235219
20346763
20400693
20412781
20417197
20439720
20454682
20503365
20554876
20596079
20727173
20730911
20733081
20843830
20932939
20943750
20944551
20978075
21035938
21048147
21084609
21124801
21128305
21146598
21246658
21248112
21267068
21273545
21289193
21303848
21343368
21350016
21362415
21420949
21451052
21521737
21533152
21539829
21552539
21562282
21571217
21594883
21613322
21677750
21698205
21731673
21731775
21771816
21784065
21803035
21831920
21844226
21858105
21858141
21886788
21896628
21903675
21925604
21930923
21945624
21949185
21965329
22007134
22045912
22102609
22110055
22110056
22115757
22159578
22182523
22223620
22228100
22307612
22308434
22326227
22354480
22370000
22383895
22410172
22419569
22421044
22461560
22474389
22485132
22491945
22511595
22513377
22514301
22521513
22522080
22578469
22609550
22613833
22627285
22669823
22677559
22698282
22705977
22723691
22738954
22835934
22836272
22860096
22880002
22884324
22932389
22984579
22993445
23041177
23103168
23193000
23201013
23226461
23240058
23284619
23362348
23362349
23418536
23426374
23459943
23515312
23536097
23555292
23606270
23614009
23616538
23685333
23690951
23720040
23762375
23763947
23816521
23874227
23920117
23974041
24003036
24010020
24027274
24142560
24332837
24335253
24431450

遺伝子オントロジー  (GO ID)

Biological Process

GO:0048854  brain morphogenesis
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0043010  camera-type eye development
GO:0030154  cell differentiation
GO:0001709  cell fate determination
GO:0071333  cellular response to glucose stimulus
GO:0090102  cochlea development
GO:0090103  cochlea morphogenesis
GO:0010001  glial cell differentiation
GO:0042472  inner ear morphogenesis
GO:0001822  kidney development
GO:0060231  mesenchymal to epithelial transition
GO:0007501  mesodermal cell fate specification
GO:0001823  mesonephros development
GO:0001656  metanephros development
GO:0007275  multicellular organismal development
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0045918  negative regulation of cytolysis
GO:0043069  negative regulation of programmed cell death
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001843  neural tube closure
GO:0002072  optic cup morphogenesis involved in camera-type eye development
GO:0021554  optic nerve development
GO:0021631  optic nerve morphogenesis
GO:0021633  optic nerve structural organization
GO:0048513  organ development
GO:0055114  oxidation reduction
GO:0090190  positive regulation of branching involved in ureteric bud morphogenesis
GO:0008284  positive regulation of cell proliferation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0048793  pronephros development
GO:0043491  protein kinase B signaling cascade
GO:0042981  regulation of apoptosis
GO:0043067  regulation of programmed cell death
GO:0006355  regulation of transcription, DNA-dependent
GO:0003406  retinal pigment epithelium development
GO:0048863  stem cell differentiation
GO:0006351  transcription, DNA-dependent
GO:0001657  ureteric bud development
GO:0001655  urogenital system development
GO:0021650  vestibulocochlear nerve formation

Cellular Component

GO:0034451  centriolar satellite
GO:0005764  lysosome
GO:0005815  microtubule organizing center
GO:0005634  nucleus
GO:0043234  protein complex
GO:0032993  protein-DNA complex
GO:0005667  transcription factor complex

Molecular Function

GO:0070742  C2H2 zinc finger domain binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0005515  protein binding
GO:0016175  superoxide-generating NADPH oxidase activity
GO:0003700  transcription factor activity