platelet derived growth factor, alpha

詳細情報を見る

同義遺伝子名

platelet derived growth factor, alpha, Pdgfa, Platelet-derived growth factor alpha polypeptide, Platelet-derived growth factor A chain precursor, PDGF-1, PDGF A-chain

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:246.60 小脳:55.30 脳幹:- 脳梁:- 松果体:- 末梢神経:248.40 脊柱:- 網膜:96.40 目:493.90 動脈:- 静脈:- リンパ節:226.80 末梢血:- 脾臓:118.50 胸腺:19.80 骨髄:102.60 脂肪:- 骨:225.40 皮膚:126.70
GeneChip 大脳:7.91 小脳:7.13 脳幹:- 脳梁:- 松果体:- 末梢神経:8.51 脊柱:8.32 網膜:7.86 目:8.34 動脈:- 静脈:8.17 リンパ節:6.56 末梢血:- 脾臓:6.79 胸腺:- 骨髄:6.17 脂肪:7.22 骨:7.18 皮膚:8.29
CAGE 大脳:2.98 小脳:- 脳幹:3.63 脳梁:- 松果体:- 末梢神経:- 脊柱:3.97 網膜:- 目:- 動脈:3.70 静脈:- リンパ節:2.64 末梢血:- 脾臓:1.49 胸腺:2.66 骨髄:- 脂肪:- 骨:2.93 皮膚:3.92
RNA-seq 大脳:7.30 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:648.90 前立腺:- 卵巣:91.90 精巣:29.60 心臓:186 骨格筋:248.60 食道:- 胃:- 腸:- 結腸:193.80     肝臓:190.10        肺:140.60    膀胱:66.20 腎臓:153.10 下垂体:25.80 甲状腺:112.50 副腎:848.90 膵臓:478.50 乳腺:205.70 唾液腺:162
GeneChip 子宮:8.02 胎盤:8.81 前立腺:8.04 卵巣:7.78 精巣:7.02 心臓:7.56 骨格筋:8.61 食道:- 胃:8.06 腸:8.43 結腸:- 肝臓:7.06 肺:9.35 膀胱:8.36 腎臓:6.96 下垂体:6.49 甲状腺:- 副腎:8.19 膵臓:8.77 乳腺:7.67 唾液腺:8.76
CAGE 子宮:3.67 胎盤:3.97 前立腺:3.26 卵巣:3.20 精巣:2.46 心臓:- 骨格筋:- 食道:- 胃:4.10 腸:3.69 結腸:3.91     肝臓:2.26    肺:4.51 膀胱:3.55 腎臓:- 下垂体:2.22 甲状腺:- 副腎:3.89 膵臓:4.13 乳腺:2.89 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:5.80 食道:- 胃:- 腸:- 結腸:-     肝臓:1.98        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0001525  angiogenesis
GO:0007596  blood coagulation
GO:0030031  cell projection assembly
GO:0048565  gut development
GO:0001942  hair follicle development
GO:0048286  lung alveolus development
GO:0007275  multicellular organismal development
GO:0050919  negative chemotaxis
GO:0010512  negative regulation of phosphatidylinositol biosynthetic process
GO:0010544  negative regulation of platelet activation
GO:0009887  organ morphogenesis
GO:0048008  platelet-derived growth factor receptor signaling pathway
GO:0051781  positive regulation of cell division
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0045740  positive regulation of DNA replication
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0048146  positive regulation of fibroblast proliferation
GO:0043406  positive regulation of MAP kinase activity
GO:0043410  positive regulation of MAPKKK cascade
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0031954  positive regulation of protein amino acid autophosphorylation
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0060683  regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling
GO:0050730  regulation of peptidyl-tyrosine phosphorylation
GO:0014910  regulation of smooth muscle cell migration
GO:0009611  response to wounding
GO:0043588  skin development

Cellular Component

GO:0009986  cell surface
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0016020  membrane
GO:0005902  microvillus

Molecular Function

GO:0005518  collagen binding
GO:0008083  growth factor activity
GO:0048407  platelet-derived growth factor binding
GO:0005161  platelet-derived growth factor receptor binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity