platelet derived growth factor, B polypeptide

同義遺伝子名

PDGF-B, Pdgfb, platelet derived growth factor, B polypeptide, Sis, c-sis, PDGF-2, Platelet-derived growth factor beta polypeptide, PDGF B-chain, Platelet-derived growth factor B chain precursor

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:3.50

小脳:-

脳幹:31.80

脳梁:-

松果体:515.60

末梢神経:38.20

脊柱:-

網膜:-

目:7.60

動脈:-

静脈:-

リンパ節:97.20

末梢血:-

脾臓:26.30

胸腺:19.80

骨髄:-

脂肪:-

骨:12.50

皮膚:-

GeneChip

大脳:7.60

小脳:6.34

脳幹:-

脳梁:-

松果体:-

末梢神経:6.46

脊柱:7.02

網膜:5.69

目:6.25

動脈:-

静脈:6.86

リンパ節:7.35

末梢血:-

脾臓:7.45

胸腺:-

骨髄:7.37

脂肪:8.29

骨:7.21

皮膚:7.45

CAGE

大脳:2.16

小脳:-

脳幹:2.24

脳梁:-

松果体:-

末梢神経:-

脊柱:2.42

網膜:-

目:-

動脈:2.63

静脈:-

リンパ節:1.98

末梢血:-

脾臓:2.27

胸腺:1.85

骨髄:-

脂肪:-

骨:2.09

皮膚:2.03

RNA-seq

大脳:4.46

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:43.60

胎盤:55.20

前立腺:-

卵巣:11.50

精巣:-

心臓:18.60

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:20.10

膀胱:-

腎臓:-

下垂体:-

甲状腺:112.50

副腎:-

膵臓:-

乳腺:32.60

唾液腺:108

GeneChip

子宮:7.52

胎盤:9.74

前立腺:6.40

卵巣:8

精巣:5.98

心臓:8.91

骨格筋:8.83

食道:-

胃:7.29

腸:6.41

結腸:-

肝臓:6.17

肺:10.15

膀胱:6.69

腎臓:7.99

下垂体:6.89

甲状腺:-

副腎:8.08

膵臓:7.95

乳腺:8.45

唾液腺:6.16

CAGE

子宮:2.30

胎盤:3.35

前立腺:1.02

卵巣:2.45

精巣:0

心臓:-

骨格筋:-

食道:-

胃:2.52

腸:1.49

結腸:2.16

肝臓:1.22

肺:4.24

膀胱:2.05

腎臓:-

下垂体:2.42

甲状腺:-

副腎:3.27

膵臓:2.33

乳腺:2.80

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:3.33

食道:-

胃:-

腸:-

結腸:-

肝臓:1.54

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_011057
Gene ID	18591
Unigene ID	Mm.144089
Probe set ID	1450414_at [Mouse430_2]
Ensembl ID	ENSMUSG00000000489

オーソログ対応遺伝子

ヒト[6]	NM_002608, NM_033016
ラット[2]	NM_031524, NM_033016

染色体

遺伝子ファミリー (Interpro ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0032147	activation of protein kinase activity
GO:0032148	activation of protein kinase B activity
GO:0007596	blood coagulation
GO:0048514	blood vessel morphogenesis
GO:0060445	branching involved in salivary gland morphogenesis
GO:0060947	cardiac vascular smooth muscle cell differentiation
GO:0060326	cell chemotaxis
GO:0030031	cell projection assembly
GO:0071363	cellular response to growth factor stimulus
GO:0071506	cellular response to mycophenolic acid
GO:0001892	embryonic placenta development
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis
GO:0007507	heart development
GO:0002548	monocyte chemotaxis
GO:0007275	multicellular organismal development
GO:0030336	negative regulation of cell migration
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process
GO:0010544	negative regulation of platelet activation
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0045908	negative regulation of vasodilation
GO:0018105	peptidyl-serine phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0048008	platelet-derived growth factor receptor signaling pathway
GO:0050918	positive chemotaxis
GO:0043536	positive regulation of blood vessel endothelial cell migration
GO:0051781	positive regulation of cell division
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0050921	positive regulation of chemotaxis
GO:0045737	positive regulation of cyclin-dependent protein kinase activity
GO:0045740	positive regulation of DNA replication
GO:0001938	positive regulation of endothelial cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
GO:0048146	positive regulation of fibroblast proliferation
GO:0003104	positive regulation of glomerular filtration
GO:0043406	positive regulation of MAP kinase activity
GO:0043410	positive regulation of MAPKKK cascade
GO:0045840	positive regulation of mitosis
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0031954	positive regulation of protein amino acid autophosphorylation
GO:0014911	positive regulation of smooth muscle cell migration
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0045907	positive regulation of vasoconstriction
GO:0006468	protein amino acid phosphorylation
GO:0050730	regulation of peptidyl-tyrosine phosphorylation
GO:0009611	response to wounding
GO:0006929	substrate-bound cell migration
GO:0007179	transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0016323	basolateral plasma membrane
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0016020	membrane

Molecular Function

GO:0042056	chemoattractant activity
GO:0005518	collagen binding
GO:0008083	growth factor activity
GO:0048407	platelet-derived growth factor binding
GO:0005161	platelet-derived growth factor receptor binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0016176	superoxide-generating NADPH oxidase activator activity

platelet derived growth factor, B polypeptide

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function