platelet derived growth factor receptor, alpha polypeptide

詳細情報を見る

同義遺伝子名

AI115593, Pdgfr-2, PDGF-R-alpha, Pdgfra, CD140a, CD140a antigen

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:119.80 小脳:110.50 脳幹:- 脳梁:- 松果体:- 末梢神経:38.20 脊柱:- 網膜:- 目:152 動脈:168.80 静脈:- リンパ節:10.80 末梢血:- 脾臓:13.20 胸腺:9.90 骨髄:- 脂肪:425.40 骨:62.60 皮膚:79.20
GeneChip 大脳:6.24 小脳:5.70 脳幹:- 脳梁:- 松果体:- 末梢神経:5.27 脊柱:6.24 網膜:4.88 目:5.39 動脈:- 静脈:7.67 リンパ節:6.78 末梢血:- 脾臓:6.23 胸腺:- 骨髄:5.19 脂肪:7.27 骨:5.68 皮膚:5.43
CAGE 大脳:2.16 小脳:- 脳幹:2.51 脳梁:- 松果体:- 末梢神経:- 脊柱:2.82 網膜:- 目:- 動脈:3.10 静脈:- リンパ節:3.21 末梢血:- 脾臓:1.89 胸腺:1.06 骨髄:- 脂肪:- 骨:1.97 皮膚:3.56
RNA-seq 大脳:2.87 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:174.50 胎盤:400.40 前立腺:61.80 卵巣:46 精巣:36.90 心臓:18.60 骨格筋:- 食道:- 胃:- 腸:- 結腸:70.50     肝臓:-        肺:30.10    膀胱:198.50 腎臓:8.10 下垂体:- 甲状腺:- 副腎:- 膵臓:140.70 乳腺:81.60 唾液腺:-
GeneChip 子宮:8.26 胎盤:9.99 前立腺:5.93 卵巣:7.96 精巣:5.98 心臓:6.59 骨格筋:5.93 食道:- 胃:6.48 腸:6.37 結腸:- 肝臓:5.65 肺:9.19 膀胱:8.08 腎臓:6.48 下垂体:5.41 甲状腺:- 副腎:5.81 膵臓:6.05 乳腺:6.56 唾液腺:5.73
CAGE 子宮:4.05 胎盤:5.03 前立腺:2.80 卵巣:3.71 精巣:0.99 心臓:- 骨格筋:- 食道:- 胃:2.52 腸:2.62 結腸:2.73     肝臓:1.45    肺:4.26 膀胱:3.88 腎臓:- 下垂体:2.01 甲状腺:- 副腎:3.13 膵臓:2.19 乳腺:2.75 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.73 食道:- 胃:- 腸:- 結腸:-     肝臓:1.68        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_011058
Gene ID 18595
Unigene ID Mm.221403
Probe set ID 1421916_at  [Mouse430_2]
Ensembl ID ENSMUSG00000029231

オーソログ対応遺伝子

ヒト[1]  NM_006206
ラット[3]  NM_012802

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

863250
1292572
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0030325  adrenal gland development
GO:0009653  anatomical structure morphogenesis
GO:0055003  cardiac myofibril assembly
GO:0060326  cell chemotaxis
GO:0016477  cell migration
GO:0071230  cellular response to amino acid stimulus
GO:0006935  chemotaxis
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0048557  embryonic digestive tract morphogenesis
GO:0008210  estrogen metabolic process
GO:0030198  extracellular matrix organization
GO:0060325  face morphogenesis
GO:0008585  female gonad development
GO:0001701  in utero embryonic development
GO:0033327  Leydig cell differentiation
GO:0030324  lung development
GO:0001553  luteinization
GO:0030539  male genitalia development
GO:0007275  multicellular organismal development
GO:0010544  negative regulation of platelet activation
GO:0042475  odontogenesis of dentine-containing tooth
GO:0009887  organ morphogenesis
GO:0060021  palate development
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0048015  phosphoinositide-mediated signaling
GO:0016310  phosphorylation
GO:0070527  platelet aggregation
GO:0048008  platelet-derived growth factor receptor signaling pathway
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0045740  positive regulation of DNA replication
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0048146  positive regulation of fibroblast proliferation
GO:0043552  positive regulation of phosphoinositide 3-kinase activity
GO:0010863  positive regulation of phospholipase C activity
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0050920  regulation of chemotaxis
GO:0048705  skeletal system morphogenesis
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway
GO:0042060  wound healing

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0009897  external side of plasma membrane
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0031226  intrinsic to plasma membrane
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0016301  kinase activity
GO:0000166  nucleotide binding
GO:0043548  phosphoinositide 3-kinase binding
GO:0005018  platelet-derived growth factor alpha-receptor activity
GO:0048407  platelet-derived growth factor binding
GO:0005161  platelet-derived growth factor receptor binding
GO:0042803  protein homodimerization activity
GO:0004672  protein kinase activity
GO:0004713  protein tyrosine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0004714  transmembrane receptor protein tyrosine kinase activity
GO:0005021  vascular endothelial growth factor receptor activity