platelet derived growth factor receptor, alpha polypeptide

詳細情報を見る

同義遺伝子名

AI115593, Pdgfr-2, PDGF-R-alpha, Pdgfra, CD140a, CD140a antigen

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:119.80

小脳:110.50

脳幹:-

脳梁:-

松果体:-

末梢神経:38.20

脊柱:-

網膜:-

目:152

動脈:168.80

静脈:-

リンパ節:10.80

末梢血:-

脾臓:13.20

胸腺:9.90

骨髄:-

脂肪:425.40

骨:62.60

皮膚:79.20

GeneChip

大脳:8.81

小脳:7.01

脳幹:-

脳梁:-

松果体:-

末梢神経:7.85

脊柱:8.21

網膜:7

目:9.34

動脈:-

静脈:11.10

リンパ節:9.23

末梢血:-

脾臓:8.97

胸腺:-

骨髄:7.09

脂肪:9.98

骨:8.91

皮膚:8.05

CAGE

大脳:2.16

小脳:-

脳幹:2.51

脳梁:-

松果体:-

末梢神経:-

脊柱:2.82

網膜:-

目:-

動脈:3.10

静脈:-

リンパ節:3.21

末梢血:-

脾臓:1.89

胸腺:1.06

骨髄:-

脂肪:-

骨:1.97

皮膚:3.56

RNA-seq

大脳:2.87

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:174.50

胎盤:400.40

前立腺:61.80

卵巣:46

精巣:36.90

心臓:18.60

骨格筋:-

食道:-

胃:-

腸:-

結腸:70.50

肝臓:-

肺:30.10

膀胱:198.50

腎臓:8.10

下垂体:-

甲状腺:-

副腎:-

膵臓:140.70

乳腺:81.60

唾液腺:-

GeneChip

子宮:11.70

胎盤:11.73

前立腺:9.71

卵巣:11.19

精巣:7.03

心臓:9.44

骨格筋:9.08

食道:-

胃:9.42

腸:9.42

結腸:-

肝臓:6.42

肺:12

膀胱:11.07

腎臓:8.69

下垂体:7.76

甲状腺:-

副腎:10.03

膵臓:8.24

乳腺:9.65

唾液腺:9.38

CAGE

子宮:4.05

胎盤:5.03

前立腺:2.80

卵巣:3.71

精巣:0.99

心臓:-

骨格筋:-

食道:-

胃:2.52

腸:2.62

結腸:2.73

肝臓:1.45

肺:4.26

膀胱:3.88

腎臓:-

下垂体:2.01

甲状腺:-

副腎:3.13

膵臓:2.19

乳腺:2.75

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.73

食道:-

胃:-

腸:-

結腸:-

肝臓:1.68

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_011058
Gene ID	18595
Unigene ID	Mm.221403
Probe set ID	1421917_at [Mouse430_2]
Ensembl ID	ENSMUSG00000029231

オーソログ対応遺伝子

ヒト[1]	NM_006206
ラット[3]	NM_012802

染色体

遺伝子ファミリー (Interpro ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0030325	adrenal gland development
GO:0009653	anatomical structure morphogenesis
GO:0055003	cardiac myofibril assembly
GO:0060326	cell chemotaxis
GO:0016477	cell migration
GO:0071230	cellular response to amino acid stimulus
GO:0006935	chemotaxis
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0048701	embryonic cranial skeleton morphogenesis
GO:0048557	embryonic digestive tract morphogenesis
GO:0008210	estrogen metabolic process
GO:0030198	extracellular matrix organization
GO:0060325	face morphogenesis
GO:0008585	female gonad development
GO:0001701	in utero embryonic development
GO:0033327	Leydig cell differentiation
GO:0030324	lung development
GO:0001553	luteinization
GO:0030539	male genitalia development
GO:0007275	multicellular organismal development
GO:0010544	negative regulation of platelet activation
GO:0042475	odontogenesis of dentine-containing tooth
GO:0009887	organ morphogenesis
GO:0060021	palate development
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0048015	phosphoinositide-mediated signaling
GO:0016310	phosphorylation
GO:0070527	platelet aggregation
GO:0048008	platelet-derived growth factor receptor signaling pathway
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0045740	positive regulation of DNA replication
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0048146	positive regulation of fibroblast proliferation
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0010863	positive regulation of phospholipase C activity
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0050920	regulation of chemotaxis
GO:0048705	skeletal system morphogenesis
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0042060	wound healing

Cellular Component

GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0031226	intrinsic to plasma membrane
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0043548	phosphoinositide 3-kinase binding
GO:0005018	platelet-derived growth factor alpha-receptor activity
GO:0048407	platelet-derived growth factor binding
GO:0005161	platelet-derived growth factor receptor binding
GO:0042803	protein homodimerization activity
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0004714	transmembrane receptor protein tyrosine kinase activity
GO:0005021	vascular endothelial growth factor receptor activity

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR020685	Tyrosine-protein kinase
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR016243	Tyrosine-protein kinase, CSF-1/PDGF receptor
IPR020933	Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain
IPR009134	Tyrosine-protein kinase, vascular endothelial growth factor receptor (VEGFR), N-terminal

platelet derived growth factor receptor, alpha polypeptide

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function