phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)

詳細情報を見る

同義遺伝子名

Pik3r1, p55alpha, p50alpha, C530050K14, p85alpha, PI3-kinase p85-subunit alpha, AA414921, PtdIns-3-kinase p85-alpha

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:39.90

小脳:-

脳幹:222.50

脳梁:-

松果体:257.80

末梢神経:19.10

脊柱:141.90

網膜:96.40

目:91.20

動脈:-

静脈:-

リンパ節:21.60

末梢血:28.80

脾臓:52.70

胸腺:49.40

骨髄:25.60

脂肪:-

骨:62.60

皮膚:15.80

GeneChip

大脳:7.20

小脳:7.51

脳幹:-

脳梁:-

松果体:-

末梢神経:7.94

脊柱:7.25

網膜:6.02

目:6.16

動脈:-

静脈:6.77

リンパ節:7.10

末梢血:-

脾臓:7.17

胸腺:-

骨髄:8.36

脂肪:7.83

骨:7.54

皮膚:8.18

CAGE

大脳:4.49

小脳:-

脳幹:4.61

脳梁:-

松果体:-

末梢神経:-

脊柱:4.95

網膜:-

目:-

動脈:5.49

静脈:-

リンパ節:4.69

末梢血:-

脾臓:4.62

胸腺:4.76

骨髄:-

脂肪:-

骨:4.41

皮膚:5.15

RNA-seq

大脳:3.71

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:27.60

前立腺:30.90

卵巣:23

精巣:-

心臓:18.60

骨格筋:-

食道:-

胃:-

腸:-

結腸:52.90

肝臓:36.20

肺:110.50

膀胱:132.40

腎臓:24.20

下垂体:142.10

甲状腺:-

副腎:-

膵臓:9.40

乳腺:146.90

唾液腺:108

GeneChip

子宮:7.64

胎盤:6.84

前立腺:6.44

卵巣:7.78

精巣:5.41

心臓:7.37

骨格筋:6.80

食道:-

胃:6.84

腸:6.78

結腸:-

肝臓:6.85

肺:6.81

膀胱:7.40

腎臓:6.93

下垂体:6.94

甲状腺:-

副腎:6.94

膵臓:6.09

乳腺:8.11

唾液腺:7.14

CAGE

子宮:5.04

胎盤:3.67

前立腺:4.60

卵巣:5.02

精巣:1.89

心臓:-

骨格筋:-

食道:-

胃:4.23

腸:4.34

結腸:4.60

肝臓:5.06

肺:4.61

膀胱:4.81

腎臓:-

下垂体:4.37

甲状腺:-

副腎:4.50

膵臓:5.10

乳腺:5.49

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.63

食道:-

胃:-

腸:-

結腸:-

肝臓:3.05

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_001077495
Gene ID	18708
Unigene ID	Mm.259333
Probe set ID	1451737_at [Mouse430_2]
Ensembl ID	ENSMUSG00000041417

オーソログ対応遺伝子

ヒト[18]	NM_001242466, NM_181504, NM_181523, NM_181524
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR008936	Rho GTPase activation protein
IPR000198	RhoGAP

遺伝子オントロジー (GO ID)

Biological Process

GO:0030183	B cell differentiation
GO:0034644	cellular response to UV
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis
GO:0006006	glucose metabolic process
GO:0060396	growth hormone receptor signaling pathway
GO:0008625	induction of apoptosis via death domain receptors
GO:0008286	insulin receptor signaling pathway
GO:0048009	insulin-like growth factor receptor signaling pathway
GO:0043066	negative regulation of apoptosis
GO:0045776	negative regulation of blood pressure
GO:0022408	negative regulation of cell-cell adhesion
GO:0001953	negative regulation of cell-matrix adhesion
GO:0010459	negative regulation of heart rate
GO:0010656	negative regulation of muscle cell apoptosis
GO:0045671	negative regulation of osteoclast differentiation
GO:0045861	negative regulation of proteolysis
GO:0048662	negative regulation of smooth muscle cell proliferation
GO:0051531	NFAT protein import into nucleus
GO:0014065	phosphoinositide 3-kinase cascade
GO:0016310	phosphorylation
GO:0030335	positive regulation of cell migration
GO:0010628	positive regulation of gene expression
GO:0045663	positive regulation of myoblast differentiation
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0032760	positive regulation of tumor necrosis factor production
GO:0006468	protein amino acid phosphorylation
GO:0043551	regulation of phosphoinositide 3-kinase activity
GO:0051591	response to cAMP
GO:0051384	response to glucocorticoid stimulus
GO:0032868	response to insulin stimulus
GO:0007165	signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005622	intracellular
GO:0016020	membrane
GO:0043005	neuron projection
GO:0005634	nucleus
GO:0005942	phosphoinositide 3-kinase complex
GO:0005886	plasma membrane
GO:0043234	protein complex

Molecular Function

GO:0016303	1-phosphatidylinositol-3-kinase activity
GO:0046935	1-phosphatidylinositol-3-kinase regulator activity
GO:0051117	ATPase binding
GO:0005516	calmodulin binding
GO:0043125	ErbB-3 class receptor binding
GO:0030331	estrogen receptor binding
GO:0043559	insulin binding
GO:0005158	insulin receptor binding
GO:0043560	insulin receptor substrate binding
GO:0005159	insulin-like growth factor receptor binding
GO:0016301	kinase activity
GO:0005168	neurotrophin TRKA receptor binding
GO:0043548	phosphoinositide 3-kinase binding
GO:0035014	phosphoinositide 3-kinase regulator activity
GO:0051219	phosphoprotein binding
GO:0005161	platelet-derived growth factor receptor binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0019904	protein domain specific binding
GO:0019901	protein kinase binding
GO:0019903	protein phosphatase binding
GO:0005102	receptor binding
GO:0030971	receptor tyrosine kinase binding
GO:0016740	transferase activity
GO:0031625	ubiquitin protein ligase binding

phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function