peroxisome proliferator activated receptor gamma

 詳細情報を見る

同義遺伝子名

peroxisome proliferator activated receptor gamma, Ppar-gamma2, PPAR-gamma, Pparg, PPAR-gamma2, Peroxisome proliferator-activated receptor gamma, Nr1c3

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:64.30 小脳:55.30 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:106.40 動脈:- 静脈:- リンパ節:10.80 末梢血:28.80 脾臓:79 胸腺:9.90 骨髄:64.10 脂肪:- 骨:25 皮膚:71.30
GeneChip 大脳:5.23 小脳:5.26 脳幹:- 脳梁:- 松果体:- 末梢神経:5.42 脊柱:5.17 網膜:4.86 目:5.11 動脈:- 静脈:5.20 リンパ節:6.52 末梢血:- 脾臓:6.12 胸腺:- 骨髄:7.16 脂肪:10.55 骨:7.44 皮膚:6.84
CAGE 大脳:0.92 小脳:- 脳幹:0.80 脳梁:- 松果体:- 末梢神経:- 脊柱:1.05 網膜:- 目:- 動脈:5.04 静脈:- リンパ節:1.73 末梢血:- 脾臓:1.97 胸腺:1.85 骨髄:- 脂肪:- 骨:1.69 皮膚:2.76
RNA-seq 大脳:1.09 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:130.90 胎盤:110.50 前立腺:61.80 卵巣:34.50 精巣:14.80 心臓:483.60 骨格筋:213 食道:- 胃:981.90 腸:961.30 結腸:475.80     肝臓:434.40        肺:50.20    膀胱:- 腎臓:338.50 下垂体:155 甲状腺:674.80 副腎:- 膵臓:84.40 乳腺:71.80 唾液腺:108
GeneChip 子宮:6.01 胎盤:9.97 前立腺:5.58 卵巣:8.59 精巣:5.24 心臓:7.48 骨格筋:6.90 食道:- 胃:9.52 腸:7.78 結腸:- 肝臓:7.16 肺:6.66 膀胱:9.36 腎臓:5.73 下垂体:5.32 甲状腺:- 副腎:8.86 膵臓:6.54 乳腺:8.70 唾液腺:5.38
CAGE 子宮:1.32 胎盤:4.38 前立腺:0.74 卵巣:2.69 精巣:1.34 心臓:- 骨格筋:- 食道:- 胃:3.39 腸:1.88 結腸:2.30     肝臓:2.48    肺:2.29 膀胱:3.19 腎臓:- 下垂体:0.70 甲状腺:- 副腎:2.42 膵臓:1.30 乳腺:2.80 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.58 食道:- 胃:- 腸:- 結腸:-     肝臓:2.61        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_011146
Gene ID 19016
Unigene ID Mm.30200
Probe set ID 1420715_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000000440

オーソログ対応遺伝子

ヒト[4]  NM_005037, NM_015869, NM_138711, NM_138712
ラット[3]  NM_001145366, NM_001145367, NM_013124, NM_138712

染色体

6E3  [115,311,239  -  115,440,419]

遺伝子ファミリー (Interpro ID)

IPR003074  Peroxisome proliferator-activated receptor
IPR003077  Peroxisome proliferator-activated receptor, gamma
IPR001723  Steroid hormone receptor
IPR013088  Zinc finger, NHR/GATA-type
IPR001628  Zinc finger, nuclear hormone receptor-type

Link to Pubmed  (Pubmed ID)

7557387
7568232
7588749
7644514
7838715
7926726
8041794
8240342
8262913
8647948
8651933
8661743
8702406
8754811
8827514
8910358
9013583
9041124
9168928
9202217
9202256
9211064
9229117
9325263
9405372
9421462
9568680
9568715
9708794
9918810
9933587
10078198
10097247
10224131
10385625
10393183
10464095
10517671
10549290
10549291
10549292
10555139
10577502
10675354
10707952
10748014
10788465
10872826
10930400
10937998
10953027
10982846
11089532
11159886
11242476
11352992
11387233
11463718
11470505
11479627
11514592
11518254
11581301
11679588
11714849
11733562
11777901
11782442
11792850
11857800
11859145
11877444
11884400
11889020
11903058
11909955
11923467
11940593
11996104
12015306
12037571
12055200
12056591
12059785
12086932
12097321
12147237
12163159
12172784
12200443
12270934
12370429
12401792
12468449
12471115
12477932
12502791
12556354
12588951
12589053
12618528
12664620
12704187
12729899
12730300
12730867
12734379
12740443
12754280
12759335
12777391
12805374
12810823
12810825
12821117
12829715
12833141
12837957
12851309
12878168
12878983
12887689
12900517
12910269
12917338
12925701
12960963
12962497
12966085
12970571
12975479
14500358
14501165
14517292
14522940
14529153
14536066
14603033
14614508
14617516
14625542
14634082
14646597
14660788
14668325
14677574
14681479
14688261
14691545
14701856
14704148
14726448
14744933
14747283
14755333
14764597
14988019
15016406
15037548
15054141
15060163
15067317
15070754
15073042
15073165
15111493
15123608
15123625
15130516
15143161
15157741
15158467
15164767
15174093
15175325
15175761
15187132
15231871
15232616
15246971
15247146
15249658
15254591
15284209
15304360
15308623
15359271
15472465
15504964
15509779
15542029
15572375
15572671
15574741
15578089
15586017
15589691
15611480
15618518
15664998
15670761
15673477
15673614
15681609
15684432
15685547
15687259
15694373
15713663
15716267
15728361
15730864
15731109
15778364
15799829
15824083
15831367
15833818
15857827
15866483
15867269
15877285
15897255
15905321
15917242
15917308
15919792
15930296
15947238
15956187
16023420
16039966
16051889
16099986
16106032
16125673
16127159
16127449
16150867
16150927
16179348
16213226
16219912
16239304
16246044
16253638
16260612
16260719
16303334
16306350
16306360
16314832
16326714
16341123
16357043
16364246
16371367
16376852
16403437
16407166
16428452
16431920
16457814
16461467
16484339
16499711
16524877
16527895
16537572
16547072
16547277
16556603
16567512
16574647
16580992
16581799
16675498
16713977
16720732
16737695
16751185
16759917
16798724
16815847
16828750
16845470
16858678
16873730
16876120
16901790
16921131
16951334
16964447
16966031
16971390
16971476
16972249
16980437
16981222
17003330
17003451
17008383
17015710
17019405
17095756
17143554
17174269
17197391
17214992
17218271
17239574
17240171
17276354
17276355
17277116
17289022
17301838
17304352
17312139
17325208
17389706
17389768
17394061
17440173
17462989
17463056
17463185
17463321
17465682
17468515
17484888
17515919
17519361
17521607
17525798
17536062
17540578
17543202
17587675
17625041
17641685
17652179
17678635
17699161
17713572
17719655
17823655
17848638
17888405
17905753
17921248
17932108
17936399
17947702
17954559
17963725
17965419
18028370
18032385
18037994
18039840
18056926
18059282
18060855
18065517
18073138
18083318
18085707
18096664
18172011
18172578
18174233
18187772
18204460
18208815
18227153
18227763
18242221
18245842
18267111
18268046
18276752
18285614
18287559
18302511
18312853
18323470
18330590
18346728
18354219
18354499
18355828
18382765
18391483
18396136
18422969
18423937
18444964
18445885
18450755
18489901
18492766
18492776
18495890
18497448
18497737
18498870
18506083
18511847
18522830
18535203
18541527
18547288
18547997
18555852
18556801
18562627
18566389
18577375
18584035
18596980
18612081
18622018
18627765
18640979
18653710
18675789
18676352
18696105
18703634
18707223
18711014
18718916
18719582
18722375
18727927
18755987
18762025
18768463
18772483
18776938
18782538
18783346
18784309
18787041
18789887
18801968
18832723
18840764
18845124
18845627
18845632
18926937
18930917
18931513
18981214
18981473
18981474
19023129
19037106
19041764
19047629
19052558
19065047
19066220
19066287
19075513
19114032
19115254
19117549
19126543
19126678
19136559
19138979
19141181
19141617
19147827
19148122
19160422
19165156
19179641
19201410
19218241
19221220
19229877
19237535
19243475
19246449
19247431
19265701
19282365
19289458
19300518
19307559
19307774
19324970
19338578
19345188
19348833
19364979
19366697
19369133
19369934
19376812
19377069
19380830
19389799
19395477
19399410
19401386
19414603
19417127
19419310
19422369
19422805
19423085
19439596
19443733
19452630
19458067
19460852
19471887
19484746
19485965
19490906
19520921
19535643
19561094
19564408
19566485
19574402
19577541
19589179
19596004
19596783
19633298
19641141
19641492
19645740
19657144
19666473
19666848
19698295
19714649
19729954
19737384
19737866
19749155
19801450
19808779
19833717
19834493
19843873
19850645
19861583
19884495
19885945
19900503
19922793
19932165
19940263
19956639
19963029
19997628
20009560
20018750
20018933
20026644
20028987
20038583
20059953
20060380
20064973
20065157
20075336
20081051
20089779
20150512
20154695
20156580
20162732
20168312
20170635
20176806
20185831
20194623
20226837
20332343
20339310
20360005
20363918
20364085
20368353
20392228
20401461
20414969
20421464
20422041
20427759
20448152
20498072
20498376
20508203
20512989
20519122
20524105
20525205
20530198
20531941
20537136
20552250
20558736
20587609
20589837
20622112
20625991
20630681
20634487
20638365
20643096
20650758
20651683
20660060
20665707
20668093
20686481
20697155
20705243
20724579
20725151
20798360
20801631
20810566
20813360
20846400
20852389
20854792
20861226
20884641
20887899
20932939
20950277
20950707
20955583
20960217
20974668
21035761
21036914
21047783
21068720
21070867
21076077
21088248
21088297
21093321
21111596
21115338
21135166
21148188
21148557
21151991
21156825
21164549
21177828
21192919
21208653
21233451
21245029
21267068
21289052
21291868
21292830
21293061
21296052
21297860
21307302
21311715
21317313
21351141
21355291
21362339
21382619
21410980
21418994
21457357
21459326
21474828
21501147
21507897
21514433
21531337
21532596
21571064
21571217
21572083
21622945
21628453
21641391
21669876
21677750
21690289
21700709
21704006
21719705
21734368
21736821
21756814
21757225
21788573
21791563
21803035
21821917
21843327
21847688
21868013
21876000
21880694
21908737
21911492
21933390
21940512
21947280
21948987
21955520
21967974
21974932
21994940
21999426
22015658
22019459
22033706
22037925
22053002
22053106
22055502
22056382
22078880
22090424
22099177
22119778
22124376
22145026
22152244
22154759
22157014
22160138
22160191
22169011
22173065
22207551
22207709
22208362
22226965
22249025
22253419
22260862
22268140
22292086
22293175
22294748
22304921
22307523
22307907
22310664
22315431
22319009
22319216
22321194
22323595
22326222
22334075
22361822
22362769
22405074
22447120
22461176
22467332
22474127
22482731
22493496
22507175
22522926
22539598
22563432
22581835
22584573
22593575
22609406
22610404
22621923
22629382
22659381
22664386
22696146
22700433
22707117
22722857
22733994
22749137
22773754
22790028
22792179
22807489
22819773
22841546
22849425
22855570
22855714
22859371
22863012
22863076
22869740
22874998
22886847
22899986
22910911
22925536
22933117
22940098
22951341
22962432
22967998
22974214
22982455
23011131
23018455
23041568
23042820
23060450
23064015
23071089
23071818
23084144
23093780
23105093
23105142
23108227
23117547
23126661
23177620
23178591
23199346
23202735
23239344
23250430
23250487
23250918
23253599
23266329
23275342
23297177
23320500
23321074
23323617
23326314
23332504
23333385
23349485
23352188
23370576
23374104
23374874
23375622
23386130
23408111
23419397
23449535
23454216
23461356
23469071
23499423
23500012
23524568
23525438
23541989
23567850
23619236
23628590
23663737
23663741
23689589
23700465
23712033
23734181
23766271
23767827
23775123
23788637
23800883
23821743
23833249
23840343
23891623
23907538
23912449
23934545
23943621
23954155
23975680
23981481
23987512
23994134
23995233
24009687
24025786
24072712
24096869
24107399
24158519
24167256
24287404
24288131
24295831
24319114
24327268
24379442
24411941
24482374
24486511
24489087
24523408
24569375
24569592
24623782
24644240

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0050873  brown fat cell differentiation
GO:0045165  cell fate commitment
GO:0048469  cell maturation
GO:0032869  cellular response to insulin stimulus
GO:0071285  cellular response to lithium ion
GO:0071407  cellular response to organic cyclic substance
GO:0030855  epithelial cell differentiation
GO:0045444  fat cell differentiation
GO:0019395  fatty acid oxidation
GO:0042593  glucose homeostasis
GO:0006954  inflammatory response
GO:0030522  intracellular receptor-mediated signaling pathway
GO:0042953  lipoprotein transport
GO:0015909  long-chain fatty acid transport
GO:0045713  low-density lipoprotein receptor biosynthetic process
GO:0030224  monocyte differentiation
GO:0002674  negative regulation of acute inflammatory response
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0010887  negative regulation of cholesterol storage
GO:0001818  negative regulation of cytokine production
GO:0060336  negative regulation of interferon-gamma-mediated signaling pathway
GO:0010745  negative regulation of macrophage derived foam cell differentiation
GO:0010871  negative regulation of receptor biosynthetic process
GO:0010891  negative regulation of sequestering of triglyceride
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0051974  negative regulation of telomerase activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001890  placenta development
GO:0045600  positive regulation of fat cell differentiation
GO:0046321  positive regulation of fatty acid oxidation
GO:0048714  positive regulation of oligodendrocyte differentiation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0008217  regulation of blood pressure
GO:0045598  regulation of fat cell differentiation
GO:0019216  regulation of lipid metabolic process
GO:0006355  regulation of transcription, DNA-dependent
GO:0033993  response to lipid
GO:0055098  response to low-density lipoprotein stimulus
GO:0032526  response to retinoic acid
GO:0007165  signal transduction
GO:0043401  steroid hormone mediated signaling pathway
GO:0006351  transcription, DNA-dependent
GO:0050872  white fat cell differentiation

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0050544  arachidonic acid binding
GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0008144  drug binding
GO:0019899  enzyme binding
GO:0004879  ligand-dependent nuclear receptor activity
GO:0030374  ligand-dependent nuclear receptor transcription coactivator activity
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0046965  retinoid X receptor binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0033613  transcription activator binding
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding