prospero-related homeobox 1

詳細情報を見る

同義遺伝子名

Prox1, Homeobox prospero-like protein PROX1, A230003G05Rik, prospero-related homeobox 1, PROX 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:10.40 小脳:18.40 脳幹:63.60 脳梁:- 松果体:- 末梢神経:- 脊柱:47.30 網膜:64.30 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:65.80 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:4.15 小脳:4.89 脳幹:- 脳梁:- 松果体:- 末梢神経:3.54 脊柱:4.46 網膜:3.88 目:4.26 動脈:- 静脈:3.62 リンパ節:4.13 末梢血:- 脾臓:3.54 胸腺:- 骨髄:3.50 脂肪:3.51 骨:3.57 皮膚:3.57
CAGE 大脳:3.47 小脳:- 脳幹:3.13 脳梁:- 松果体:- 末梢神経:- 脊柱:3.15 網膜:- 目:- 動脈:1.53 静脈:- リンパ節:3.67 末梢血:- 脾臓:1.76 胸腺:0.49 骨髄:- 脂肪:- 骨:0.63 皮膚:1.63
RNA-seq 大脳:2.32 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:148.80 骨格筋:- 食道:- 胃:65.50 腸:37 結腸:-     肝臓:45.30        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:18.80 乳腺:- 唾液腺:-
GeneChip 子宮:3.56 胎盤:3.58 前立腺:3.78 卵巣:3.71 精巣:5.77 心臓:6.36 骨格筋:3.64 食道:- 胃:3.59 腸:3.55 結腸:- 肝臓:6.18 肺:3.57 膀胱:3.49 腎臓:3.90 下垂体:4.26 甲状腺:- 副腎:3.83 膵臓:3.60 乳腺:3.65 唾液腺:3.49
CAGE 子宮:1.58 胎盤:0.56 前立腺:0.74 卵巣:1.76 精巣:3.77 心臓:- 骨格筋:- 食道:- 胃:0 腸:1.36 結腸:1.27     肝臓:4.89    肺:1.17 膀胱:1.20 腎臓:- 下垂体:3.30 甲状腺:- 副腎:3.34 膵臓:1.61 乳腺:1.44 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.32 食道:- 胃:- 腸:- 結腸:-     肝臓:4.79        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_008937
Gene ID 19130
Unigene ID Mm.392678
Probe set ID 1421336_at  [Mouse430_2]
Ensembl ID ENSMUSG00000010175

オーソログ対応遺伝子

ヒト[1]  NM_002763
ラット[1]  NM_001107201

染色体

-

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7821514
7908825
8951061
8995756
9703987
9876174
10080188
10349636
10499794
10603348
10631168
10639171
10652278
10677506
10707971
10888866
11042159
11069887
11076861
11217851
11493524
11683995
11825874
11850194
11927535
11983855
12072567
12183377
12351178
12426373
12466851
12477932
12522250
12692551
12816048
12834871
12853470
14634646
14715945
14736742
14736744
15084498
15147765
15163631
15232737
15261829
15322537
15342729
15363391
15381696
15465483
15489334
15509764
15580619
15604100
15618518
15739227
15782199
15858069
15882861
15917450
15976303
16122728
16141072
16141073
16170315
16199865
16291864
16446698
16470382
16502417
16538679
16539717
16602821
16678147
16818446
16919269
17066077
17075007
17092954
17107998
17117437
17117441
17123502
17287396
17299096
17368742
17395646
17410548
17468181
17480014
17493607
17540175
17554007
17576138
17604700
17609113
17644613
17823936
17908929
17916349
17936262
17969168
18094027
18094249
18097475
18213584
18287559
18291358
18302773
18304521
18367606
18385072
18411305
18424556
18430230
18448566
18455124
18455718
18465790
18502050
18514180
18521945
18570254
18579678
18579736
18580962
18620078
18635606
18652815
18652817
18694563
18757513
18778700
18786638
18815287
18816838
18836739
18924607
18931657
18940586
18985738
19007884
19011097
19020026
19020049
19022256
19023449
19030180
19033471
19056883
19060331
19088125
19091769
19097184
19103804
19233265
19334279
19386638
19398761
19409883
19416500
19515696
19556507
19570848
19619645
19623612
19666824
19681134
19686679
19692620
19705443
19743445
19748502
19766716
19825936
19890917
19901262
19906871
19938109
19944164
20027181
20027618
20059953
20105280
20110424
20144606
20152827
20181838
20186345
20194433
20215346
20223757
20230750
20237275
20308569
20360386
20364082
20382171
20407033
20427652
20436479
20453716
20463215
20512592
20558617
20584329
20610746
20621054
20713964
20808958
20843830
20932899
20932939
20949055
20978081
21040746
21087508
21118511
21146598
21166921
21181199
21192082
21203589
21233129
21267068
21280160
21300049
21375603
21420948
21436036
21436445
21451052
21452232
21472479
21472480
21504908
21515254
21536023
21558380
21562282
21601656
21632926
21677750
21705651
21731503
21743007
21778431
21795542
21807945
21857657
21932312
21985497
21991391
22012621
22096492
22157817
22159122
22171010
22173065
22174793
22178591
22230615
22232212
22235033
22235191
22240097
22241837
22252499
22258620
22275127
22306086
22354871
22354878
22374700
22378868
22411557
22412967
22491411
22503753
22508481
22538088
22573682
22613570
22622036
22647876
22753134
22791897
22827438
22855803
22859612
22975310
23056351
23136392
23192966
23223288
23226461
23299940
23341894
23345230
23393595
23426374
23426945
23447624
23482492
23483698
23554936
23589895
23595735
23614009
23615281
23653198
23761906
23776487
23813480
23828756
23850867
23863479
23926259
23946445
23946447
24019067
24023676
24038449
24101523
24133138
24140542
24155945
24161570
24292710
24361262
24449835
24493818
24523456
24523460
24530424

遺伝子オントロジー  (GO ID)

Biological Process

GO:0060414  aorta smooth muscle tissue morphogenesis
GO:0055009  atrial cardiac muscle tissue morphogenesis
GO:0001709  cell fate determination
GO:0021707  cerebellar granule cell differentiation
GO:0021542  dentate gyrus development
GO:0060214  endocardium formation
GO:0045446  endothelial cell differentiation
GO:0048839  inner ear development
GO:0070309  lens fiber cell morphogenesis
GO:0002089  lens morphogenesis in camera-type eye
GO:0001945  lymph vessel development
GO:0001946  lymphangiogenesis
GO:0060836  lymphatic endothelial cell differentiation
GO:0007275  multicellular organismal development
GO:0030240  muscle thin filament assembly
GO:0070858  negative regulation of bile acid biosynthetic process
GO:0008285  negative regulation of cell proliferation
GO:0043433  negative regulation of transcription factor activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0045071  negative regulation of viral genome replication
GO:0045787  positive regulation of cell cycle
GO:0008284  positive regulation of cell proliferation
GO:0045737  positive regulation of cyclin-dependent protein kinase activity
GO:0010595  positive regulation of endothelial cell migration
GO:0001938  positive regulation of endothelial cell proliferation
GO:0060421  positive regulation of heart growth
GO:0060298  positive regulation of sarcomere organization
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0010468  regulation of gene expression
GO:0060849  regulation of transcription involved in lymphatic endothelial cell fate commitment
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent
GO:0048845  venous blood vessel morphogenesis
GO:0055010  ventricular cardiac muscle tissue morphogenesis
GO:0055005  ventricular cardiac myofibril development
GO:0060412  ventricular septum morphogenesis

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0050692  DBD domain binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0050693  LBD domain binding
GO:0016922  ligand-dependent nuclear receptor binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity