presenilin 2

詳細情報を見る

同義遺伝子名

ALG-3, presenilin 2, Ad4h, Psen2, Presenilin-2, AI266870, PS-2, Psnl2, Ps-2, Alg3

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:10.40

小脳:18.40

脳幹:31.80

脳梁:-

松果体:-

末梢神経:19.10

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:97.20

末梢血:43.10

脾臓:105.30

胸腺:19.80

骨髄:-

脂肪:212.70

骨:12.50

皮膚:126.70

GeneChip

大脳:7.28

小脳:7.95

脳幹:-

脳梁:-

松果体:-

末梢神経:9.07

脊柱:7.62

網膜:7.82

目:8.12

動脈:-

静脈:7.42

リンパ節:9.34

末梢血:-

脾臓:8.96

胸腺:-

骨髄:8.19

脂肪:8.24

骨:7.81

皮膚:6.53

CAGE

大脳:1.88

小脳:-

脳幹:1.87

脳梁:-

松果体:-

末梢神経:-

脊柱:2.21

網膜:-

目:-

動脈:1.80

静脈:-

リンパ節:2.77

末梢血:-

脾臓:2.56

胸腺:0.82

骨髄:-

脂肪:-

骨:0.63

皮膚:1.50

RNA-seq

大脳:5.40

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:87.20

胎盤:-

前立腺:-

卵巣:57.50

精巣:22.20

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:307.70

肺:30.10

膀胱:-

腎臓:-

下垂体:64.60

甲状腺:-

副腎:-

膵臓:46.90

乳腺:29.40

唾液腺:-

GeneChip

子宮:7.94

胎盤:8

前立腺:8.63

卵巣:8.85

精巣:6.73

心臓:7.86

骨格筋:7.49

食道:-

胃:8.11

腸:7.40

結腸:-

肝臓:11.46

肺:8.58

膀胱:7.69

腎臓:7.75

下垂体:8.69

甲状腺:-

副腎:7.92

膵臓:9.35

乳腺:7.84

唾液腺:7.48

CAGE

子宮:2.14

胎盤:1.80

前立腺:3.53

卵巣:2.72

精巣:0.99

心臓:-

骨格筋:-

食道:-

胃:1.57

腸:1.05

結腸:1.63

肝臓:4.94

肺:2.17

膀胱:1.83

腎臓:-

下垂体:2.83

甲状腺:-

副腎:2.29

膵臓:3.64

乳腺:2.21

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:2.34

食道:-

胃:-

腸:-

結腸:-

肝臓:31.91

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_011183
Gene ID	19165
Unigene ID	Mm.330850
Probe set ID	1425869_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000010609

オーソログ対応遺伝子

ヒト[6]	NM_000447, NM_012486
ラット [0]

染色体

1H4 [182,157,135 - 182,193,569]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR006639	Peptidase A22, presenilin signal peptide
IPR001108	Peptidase A22A, presenilin
IPR001493	Peptidase A22A, presenilin 2

遺伝子オントロジー (GO ID)

Biological Process

GO:0042987	amyloid precursor protein catabolic process
GO:0042640	anagen
GO:0050435	beta-amyloid metabolic process
GO:0048854	brain morphogenesis
GO:0006816	calcium ion transport
GO:0060048	cardiac muscle contraction
GO:0001708	cell fate specification
GO:0044267	cellular protein metabolic process
GO:0021904	dorsal/ventral neural tube patterning
GO:0009790	embryonic development
GO:0030326	embryonic limb morphogenesis
GO:0032469	endoplasmic reticulum calcium ion homeostasis
GO:0030900	forebrain development
GO:0001942	hair follicle development
GO:0002244	hemopoietic progenitor cell differentiation
GO:0007611	learning or memory
GO:0040011	locomotion
GO:0048286	lung alveolus development
GO:0006509	membrane protein ectodomain proteolysis
GO:0007613	memory
GO:0002573	myeloid leukocyte differentiation
GO:0043066	negative regulation of apoptosis
GO:0007175	negative regulation of epidermal growth factor receptor activity
GO:0001933	negative regulation of protein amino acid phosphorylation
GO:0032091	negative regulation of protein binding
GO:0031333	negative regulation of protein complex assembly
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0051444	negative regulation of ubiquitin-protein ligase activity
GO:0007220	Notch receptor processing
GO:0007219	Notch signaling pathway
GO:0043065	positive regulation of apoptosis
GO:0043085	positive regulation of catalytic activity
GO:0050820	positive regulation of coagulation
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0001921	positive regulation of receptor recycling
GO:0051604	protein maturation
GO:0016485	protein processing
GO:0015031	protein transport
GO:0006508	proteolysis
GO:0007176	regulation of epidermal growth factor receptor activity
GO:0043393	regulation of protein binding
GO:0048167	regulation of synaptic plasticity
GO:0043589	skin morphogenesis
GO:0001756	somitogenesis
GO:0002286	T cell activation during immune response
GO:0050852	T cell receptor signaling pathway
GO:0048538	thymus development

Cellular Component

GO:0016324	apical plasma membrane
GO:0030424	axon
GO:0005938	cell cortex
GO:0043025	cell soma
GO:0009986	cell surface
GO:0005813	centrosome
GO:0035253	ciliary rootlet
GO:0005829	cytosol
GO:0043198	dendritic shaft
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0030426	growth cone
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0000776	kinetochore
GO:0005765	lysosomal membrane
GO:0016020	membrane
GO:0045121	membrane raft
GO:0005743	mitochondrial inner membrane
GO:0031594	neuromuscular junction
GO:0005637	nuclear inner membrane
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0043234	protein complex
GO:0030018	Z disc

Molecular Function

GO:0004190	aspartic-type endopeptidase activity
GO:0004175	endopeptidase activity
GO:0016787	hydrolase activity
GO:0008233	peptidase activity
GO:0005515	protein binding

presenilin 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function