prostaglandin-endoperoxide synthase 2

 詳細情報を見る

同義遺伝子名

TIS10 protein, Tis10, PHS-2, COX-2, cyclooxygenase-2, PES-2, Pghs2, Pghs-b, Gripghs, PGHS-2, Prostaglandin H2 synthase 2, prostaglandin G/H synthase, PGH synthase 2, prostaglandin-endoperoxide synthase 2, PHS II, Cox-2, cyclooxygenase 2, Cox2, Cyclooxygenase-2, COX2, Prostaglandin G/H synthase 2 precursor, TIS10, Prostaglandin-endoperoxide synthase 2, Ptgs2

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:5.20 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:118.80 末梢血:14.40 脾臓:79 胸腺:- 骨髄:448.80 脂肪:- 骨:- 皮膚:23.80
GeneChip 大脳:5.71 小脳:3.72 脳幹:- 脳梁:- 松果体:- 末梢神経:3.93 脊柱:3.86 網膜:3.81 目:4.56 動脈:- 静脈:5.25 リンパ節:3.92 末梢血:- 脾臓:3.87 胸腺:- 骨髄:3.84 脂肪:4.11 骨:4.08 皮膚:4.31
CAGE 大脳:2.35 小脳:- 脳幹:1.43 脳梁:- 松果体:- 末梢神経:- 脊柱:0.83 網膜:- 目:- 動脈:2.48 静脈:- リンパ節:3.18 末梢血:- 脾臓:0 胸腺:2.44 骨髄:- 脂肪:- 骨:0 皮膚:1.67
RNA-seq 大脳:1.24 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:41.40 前立腺:- 卵巣:- 精巣:7.40 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:251    膀胱:132.40 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:9.40 乳腺:160 唾液腺:-
GeneChip 子宮:7.13 胎盤:7.95 前立腺:5.13 卵巣:4.45 精巣:3.75 心臓:4.34 骨格筋:4.15 食道:- 胃:5.11 腸:6.04 結腸:- 肝臓:4.14 肺:6.99 膀胱:8.38 腎臓:3.71 下垂体:3.75 甲状腺:- 副腎:4.84 膵臓:4.15 乳腺:3.82 唾液腺:4.21
CAGE 子宮:4.39 胎盤:3.71 前立腺:1.51 卵巣:1.35 精巣:0 心臓:- 骨格筋:- 食道:- 胃:2.26 腸:1.96 結腸:1.89     肝臓:0    肺:2.59 膀胱:2.27 腎臓:- 下垂体:0.29 甲状腺:- 副腎:2.06 膵臓:0 乳腺:0.56 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.87 食道:- 胃:- 腸:- 結腸:-     肝臓:0        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_011198
Gene ID 19225
Unigene ID Mm.292547
Probe set ID 1417262_at  [Mouse430_2]
Ensembl ID ENSMUSG00000032487

オーソログ対応遺伝子

ヒト[1]  NM_000963
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

IPR000742  EGF-like, type 3
IPR010255  Haem peroxidase
IPR002007  Haem peroxidase, animal
IPR019791  Haem peroxidase, animal, subgroup

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0042640  anagen
GO:0001525  angiogenesis
GO:0030282  bone mineralization
GO:0050873  brown fat cell differentiation
GO:0019371  cyclooxygenase pathway
GO:0046697  decidualization
GO:0007566  embryo implantation
GO:0006633  fatty acid biosynthetic process
GO:0006631  fatty acid metabolic process
GO:0006954  inflammatory response
GO:0030216  keratinocyte differentiation
GO:0007612  learning
GO:0006629  lipid metabolic process
GO:0007613  memory
GO:0051926  negative regulation of calcium ion transport
GO:0045786  negative regulation of cell cycle
GO:0008285  negative regulation of cell proliferation
GO:0045986  negative regulation of smooth muscle contraction
GO:0032227  negative regulation of synaptic transmission, dopaminergic
GO:0030728  ovulation
GO:0055114  oxidation reduction
GO:0043065  positive regulation of apoptosis
GO:0010942  positive regulation of cell death
GO:0090050  positive regulation of cell migration involved in sprouting angiogenesis
GO:0008284  positive regulation of cell proliferation
GO:0031622  positive regulation of fever
GO:0042346  positive regulation of NF-kappaB import into nucleus
GO:0045429  positive regulation of nitric oxide biosynthetic process
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045987  positive regulation of smooth muscle contraction
GO:0031915  positive regulation of synaptic plasticity
GO:0051968  positive regulation of synaptic transmission, glutamatergic
GO:0045907  positive regulation of vasoconstriction
GO:0010575  positive regulation vascular endothelial growth factor production
GO:0001516  prostaglandin biosynthetic process
GO:0006693  prostaglandin metabolic process
GO:0008217  regulation of blood pressure
GO:0042127  regulation of cell proliferation
GO:0034097  response to cytokine stimulus
GO:0032496  response to lipopolysaccharide
GO:0006979  response to oxidative stress
GO:0019233  sensory perception of pain

Cellular Component

GO:0005901  caveola
GO:0005737  cytoplasm
GO:0005783  endoplasmic reticulum
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0019899  enzyme binding
GO:0020037  heme binding
GO:0008289  lipid binding
GO:0046872  metal ion binding
GO:0016491  oxidoreductase activity
GO:0016702  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0004601  peroxidase activity
GO:0004666  prostaglandin-endoperoxide synthase activity
GO:0042803  protein homodimerization activity