protein tyrosine phosphatase, non-receptor type 2

詳細情報を見る

同義遺伝子名

Ptpt, Ptpn2, protein tyrosine phosphatase, non-receptor type 2, Protein-tyrosine phosphatase PTP-2, TC-PTP, AI325124, Tyrosine-protein phosphatase non-receptor type 2, MPTP

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:33 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:19.10 脊柱:- 網膜:128.60 目:60.80 動脈:- 静脈:- リンパ節:43.20 末梢血:143.80 脾臓:171.20 胸腺:128.40 骨髄:179.50 脂肪:- 骨:37.60 皮膚:63.30
GeneChip 大脳:7.31 小脳:7.71 脳幹:- 脳梁:- 松果体:- 末梢神経:6.88 脊柱:6.87 網膜:8.87 目:8.39 動脈:- 静脈:8.29 リンパ節:9.43 末梢血:- 脾臓:9.06 胸腺:- 骨髄:9.06 脂肪:8.20 骨:8.94 皮膚:8.41
CAGE 大脳:3.50 小脳:- 脳幹:2.98 脳梁:- 松果体:- 末梢神経:- 脊柱:2.98 網膜:- 目:- 動脈:3.49 静脈:- リンパ節:4.48 末梢血:- 脾臓:3.50 胸腺:3.62 骨髄:- 脂肪:- 骨:3.52 皮膚:3.37
RNA-seq 大脳:3.12 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:174.50 胎盤:165.70 前立腺:30.90 卵巣:91.90 精巣:66.50 心臓:93 骨格筋:- 食道:- 胃:65.50 腸:- 結腸:17.60     肝臓:18.10        肺:50.20    膀胱:- 腎臓:16.10 下垂体:25.80 甲状腺:- 副腎:- 膵臓:37.50 乳腺:75.10 唾液腺:-
GeneChip 子宮:8.62 胎盤:9.41 前立腺:8.29 卵巣:8.62 精巣:8.54 心臓:8.11 骨格筋:8.25 食道:- 胃:8.18 腸:8.75 結腸:- 肝臓:7.76 肺:8.34 膀胱:8.15 腎臓:7.72 下垂体:8.31 甲状腺:- 副腎:8.52 膵臓:7.71 乳腺:8.40 唾液腺:8.50
CAGE 子宮:3.60 胎盤:3.70 前立腺:3.32 卵巣:3.65 精巣:3.78 心臓:- 骨格筋:- 食道:- 胃:3.39 腸:3.42 結腸:3.45     肝臓:3.45    肺:3.38 膀胱:3.16 腎臓:- 下垂体:3.53 甲状腺:- 副腎:3.60 膵臓:2.66 乳腺:3.44 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:3.50 食道:- 胃:- 腸:- 結腸:-     肝臓:2.73        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030183  B cell differentiation
GO:0016311  dephosphorylation
GO:0030218  erythrocyte differentiation
GO:0042593  glucose homeostasis
GO:0008286  insulin receptor signaling pathway
GO:0008285  negative regulation of cell proliferation
GO:0050922  negative regulation of chemotaxis
GO:0042059  negative regulation of epidermal growth factor receptor signaling pathway
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0050728  negative regulation of inflammatory response
GO:0046627  negative regulation of insulin receptor signaling pathway
GO:0060336  negative regulation of interferon-gamma-mediated signaling pathway
GO:0070104  negative regulation of interleukin-6-mediated signaling pathway
GO:0010888  negative regulation of lipid storage
GO:0045650  negative regulation of macrophage differentiation
GO:0050860  negative regulation of T cell receptor signaling pathway
GO:0010804  negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0060339  negative regulation of type I interferon-mediated signaling pathway
GO:0042518  negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0042524  negative regulation of tyrosine phosphorylation of Stat5 protein
GO:0042527  negative regulation of tyrosine phosphorylation of Stat6 protein
GO:0045722  positive regulation of gluconeogenesis
GO:0006470  protein amino acid dephosphorylation
GO:0030217  T cell differentiation

Cellular Component

GO:0005737  cytoplasm
GO:0005783  endoplasmic reticulum
GO:0005793  ER-Golgi intermediate compartment
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0016787  hydrolase activity
GO:0005178  integrin binding
GO:0004726  non-membrane spanning protein tyrosine phosphatase activity
GO:0016791  phosphatase activity
GO:0004721  phosphoprotein phosphatase activity
GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0004725  protein tyrosine phosphatase activity
GO:0030971  receptor tyrosine kinase binding
GO:0019905  syntaxin binding