retinoic acid receptor, alpha

詳細情報を見る

同義遺伝子名

retinoic acid receptor, alpha, RAR-alpha, RAR, Retinoic acid receptor alpha, RAR alpha 1, RARalpha1, Rara, Nr1b1

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:5.20

小脳:-

脳幹:-

脳梁:-

松果体:257.80

末梢神経:95.50

脊柱:-

網膜:32.10

目:15.20

動脈:84.40

静脈:-

リンパ節:324

末梢血:-

脾臓:79

胸腺:187.70

骨髄:-

脂肪:-

骨:-

皮膚:47.50

GeneChip

大脳:5.29

小脳:5.74

脳幹:-

脳梁:-

松果体:-

末梢神経:5.27

脊柱:5.51

網膜:5.10

目:5.42

動脈:-

静脈:6.01

リンパ節:6.89

末梢血:-

脾臓:6.94

胸腺:-

骨髄:6.59

脂肪:5.92

骨:5.88

皮膚:5.75

CAGE

大脳:2.92

小脳:-

脳幹:2.36

脳梁:-

松果体:-

末梢神経:-

脊柱:2.40

網膜:-

目:-

動脈:3.31

静脈:-

リンパ節:4.12

末梢血:-

脾臓:3.56

胸腺:3.70

骨髄:-

脂肪:-

骨:3.79

皮膚:3.63

RNA-seq

大脳:1.78

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:55.20

前立腺:-

卵巣:-

精巣:-

心臓:18.60

骨格筋:-

食道:-

胃:163.60

腸:-

結腸:17.60

肝臓:27.20

肺:-

膀胱:132.40

腎臓:32.20

下垂体:25.80

甲状腺:-

副腎:-

膵臓:37.50

乳腺:35.90

唾液腺:-

GeneChip

子宮:6.57

胎盤:5.87

前立腺:5.86

卵巣:5.87

精巣:6.44

心臓:6.14

骨格筋:6.01

食道:-

胃:6.35

腸:6.44

結腸:-

肝臓:6.08

肺:6.57

膀胱:5.76

腎臓:6.30

下垂体:6.05

甲状腺:-

副腎:5.36

膵臓:6.32

乳腺:5.67

唾液腺:5.63

CAGE

子宮:4.13

胎盤:2.62

前立腺:2.64

卵巣:3.70

精巣:3.11

心臓:-

骨格筋:-

食道:-

胃:4.13

腸:3.25

結腸:3.64

肝臓:3.25

肺:4.25

膀胱:3.44

腎臓:-

下垂体:3.05

甲状腺:-

副腎:3.56

膵臓:2.90

乳腺:2.68

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.93

食道:-

胃:-

腸:-

結腸:-

肝臓:2.52

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_009024
Gene ID	19401
Unigene ID	Mm.439744
Probe set ID	1450180_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000037992

オーソログ対応遺伝子

ヒト[16]	NM_000964, NM_001024809, NM_001145301, NM_001145302
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR003070	Orphan nuclear receptor
IPR003078	Retinoic acid receptor
IPR000003	Retinoid X receptor
IPR001723	Steroid hormone receptor
IPR001728	Thyroid hormone receptor
IPR013088	Zinc finger, NHR/GATA-type
IPR001628	Zinc finger, nuclear hormone receptor-type

遺伝子オントロジー (GO ID)

Biological Process

GO:0043277	apoptotic cell clearance
GO:0071391	cellular response to estrogen stimulus
GO:0071222	cellular response to lipopolysaccharide
GO:0071300	cellular response to retinoic acid
GO:0060591	chondroblast differentiation
GO:0030520	estrogen receptor signaling pathway
GO:0007281	germ cell development
GO:0003417	growth plate cartilage development
GO:0030522	intracellular receptor-mediated signaling pathway
GO:0008584	male gonad development
GO:0035264	multicellular organism growth
GO:0045596	negative regulation of cell differentiation
GO:0008285	negative regulation of cell proliferation
GO:0010629	negative regulation of gene expression
GO:0030853	negative regulation of granulocyte differentiation
GO:0032689	negative regulation of interferon-gamma production
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0017148	negative regulation of translation
GO:0045947	negative regulation of translational initiation
GO:0032720	negative regulation of tumor necrosis factor production
GO:0051099	positive regulation of binding
GO:0045787	positive regulation of cell cycle
GO:0008284	positive regulation of cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0010628	positive regulation of gene expression
GO:0032736	positive regulation of interleukin-13 production
GO:0032753	positive regulation of interleukin-4 production
GO:0032754	positive regulation of interleukin-5 production
GO:0045666	positive regulation of neuron differentiation
GO:0014068	positive regulation of phosphoinositide 3-kinase cascade
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0045630	positive regulation of T-helper 2 cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006468	protein amino acid phosphorylation
GO:0042981	regulation of apoptosis
GO:0030852	regulation of granulocyte differentiation
GO:0031641	regulation of myelination
GO:0043551	regulation of phosphoinositide 3-kinase activity
GO:0048167	regulation of synaptic plasticity
GO:0006355	regulation of transcription, DNA-dependent
GO:0032355	response to estradiol stimulus
GO:0045471	response to ethanol
GO:0032526	response to retinoic acid
GO:0048384	retinoic acid receptor signaling pathway
GO:0060010	Sertoli cell fate commitment
GO:0007165	signal transduction
GO:0007283	spermatogenesis
GO:0043401	steroid hormone mediated signaling pathway
GO:0006351	transcription, DNA-dependent
GO:0001657	ureteric bud development
GO:0055012	ventricular cardiac muscle cell differentiation

Cellular Component

GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0043005	neuron projection
GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm

Molecular Function

GO:0031490	chromatin DNA binding
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0008144	drug binding
GO:0019899	enzyme binding
GO:0004879	ligand-dependent nuclear receptor activity
GO:0046872	metal ion binding
GO:0048027	mRNA 5'-UTR binding
GO:0035014	phosphoinositide 3-kinase regulator activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0046982	protein heterodimerization activity
GO:0051018	protein kinase A binding
GO:0043422	protein kinase B binding
GO:0005102	receptor binding
GO:0001972	retinoic acid binding
GO:0003708	retinoic acid receptor activity
GO:0043565	sequence-specific DNA binding
GO:0003707	steroid hormone receptor activity
GO:0003713	transcription coactivator activity
GO:0003714	transcription corepressor activity
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding
GO:0000900	translation repressor activity, nucleic acid binding
GO:0008270	zinc ion binding

retinoic acid receptor, alpha

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function