retinoblastoma 1

 詳細情報を見る

同義遺伝子名

Rb, retinoblastoma 1, RB, Retinoblastoma-associated protein, PP105, Rb-1, pRb, RB-1, Rb1

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:45.20 小脳:18.40 脳幹:- 脳梁:- 松果体:257.80 末梢神経:19.10 脊柱:- 網膜:- 目:45.60 動脈:- 静脈:- リンパ節:97.20 末梢血:28.80 脾臓:26.30 胸腺:98.80 骨髄:12.80 脂肪:212.70 骨:50.10 皮膚:15.80
GeneChip 大脳:7.67 小脳:7.53 脳幹:- 脳梁:- 松果体:- 末梢神経:8.09 脊柱:7.74 網膜:8.58 目:8.70 動脈:- 静脈:7.62 リンパ節:8.92 末梢血:- 脾臓:8.57 胸腺:- 骨髄:10.69 脂肪:9.18 骨:10.58 皮膚:8.59
CAGE 大脳:3.82 小脳:- 脳幹:3.35 脳梁:- 松果体:- 末梢神経:- 脊柱:3.49 網膜:- 目:- 動脈:3.98 静脈:- リンパ節:4.45 末梢血:- 脾臓:4.55 胸腺:4.25 骨髄:- 脂肪:- 骨:4.43 皮膚:4.05
RNA-seq 大脳:2.27 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:13.80 前立腺:- 卵巣:137.90 精巣:14.80 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:18.10        肺:60.30    膀胱:- 腎臓:8.10 下垂体:25.80 甲状腺:- 副腎:- 膵臓:37.50 乳腺:75.10 唾液腺:-
GeneChip 子宮:7.36 胎盤:8.44 前立腺:7.64 卵巣:8.19 精巣:6.81 心臓:7.57 骨格筋:7.75 食道:- 胃:8.05 腸:8.75 結腸:- 肝臓:6.47 肺:8.16 膀胱:7.78 腎臓:7.84 下垂体:7.48 甲状腺:- 副腎:8.21 膵臓:6.90 乳腺:8.76 唾液腺:7.19
CAGE 子宮:2.94 胎盤:2.88 前立腺:2.61 卵巣:3.29 精巣:3.35 心臓:- 骨格筋:- 食道:- 胃:3.09 腸:3.88 結腸:3.92     肝臓:2.60    肺:3.80 膀胱:3.26 腎臓:- 下垂体:3.42 甲状腺:- 副腎:2.78 膵臓:3.16 乳腺:3.48 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.37 食道:- 胃:- 腸:- 結腸:-     肝臓:1.68        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_009029
Gene ID 19645
Unigene ID Mm.273862
Probe set ID 1417850_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022105

オーソログ対応遺伝子

ヒト[2]  NM_000321
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

IPR011028  Cyclin-like
IPR013763  Cyclin-related

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007049  cell cycle
GO:0007050  cell cycle arrest
GO:0051301  cell division
GO:0048667  cell morphogenesis involved in neuron differentiation
GO:0016568  chromatin modification
GO:0043353  enucleate erythrocyte differentiation
GO:0000082  G1/S transition of mitotic cell cycle
GO:0034349  glial cell apoptosis
GO:0048565  gut development
GO:0034088  maintenance of mitotic sister chromatid cohesion
GO:0045445  myoblast differentiation
GO:0045786  negative regulation of cell cycle
GO:0008285  negative regulation of cell proliferation
GO:0050680  negative regulation of epithelial cell proliferation
GO:0006469  negative regulation of protein kinase activity
GO:0045879  negative regulation of smoothened signaling pathway
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0051402  neuron apoptosis
GO:0030182  neuron differentiation
GO:0042551  neuron maturation
GO:0031175  neuron projection development
GO:0045651  positive regulation of macrophage differentiation
GO:0045842  positive regulation of mitotic metaphase/anaphase transition
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0071459  protein localization to centromere
GO:0051726  regulation of cell cycle
GO:0043550  regulation of lipid kinase activity
GO:0007346  regulation of mitotic cell cycle
GO:0006355  regulation of transcription, DNA-dependent
GO:0031134  sister chromatid biorientation
GO:0051146  striated muscle cell differentiation
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus
GO:0016605  PML body
GO:0035189  Rb-E2F complex
GO:0005819  spindle
GO:0005667  transcription factor complex

Molecular Function

GO:0003677  DNA binding
GO:0019899  enzyme binding
GO:0019900  kinase binding
GO:0051219  phosphoprotein binding
GO:0005515  protein binding
GO:0008134  transcription factor binding
GO:0031625  ubiquitin protein ligase binding