forkhead box P3

 詳細情報を見る

同義遺伝子名

scurfin, Scurfin, sf, forkhead box P3, JM2, Foxp3, Forkhead box protein P3

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:5.20 小脳:165.80 脳幹:95.30 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:7.60 動脈:84.40 静脈:- リンパ節:- 末梢血:28.80 脾臓:26.30 胸腺:69.20 骨髄:- 脂肪:- 骨:- 皮膚:7.90
GeneChip 大脳:3.67 小脳:3.94 脳幹:- 脳梁:- 松果体:- 末梢神経:3.79 脊柱:3.71 網膜:4.06 目:3.95 動脈:- 静脈:3.58 リンパ節:4.43 末梢血:- 脾臓:3.96 胸腺:- 骨髄:3.78 脂肪:3.66 骨:3.70 皮膚:3.65
CAGE 大脳:0 小脳:- 脳幹:0.07 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0 静脈:- リンパ節:4.46 末梢血:- 脾臓:2.01 胸腺:1.17 骨髄:- 脂肪:- 骨:1.02 皮膚:0.40
RNA-seq 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:9.10        肺:20.10    膀胱:66.20 腎臓:- 下垂体:12.90 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:3.63 胎盤:3.78 前立腺:3.92 卵巣:3.58 精巣:3.75 心臓:3.88 骨格筋:3.94 食道:- 胃:3.79 腸:3.68 結腸:- 肝臓:4.22 肺:3.80 膀胱:3.56 腎臓:3.70 下垂体:3.58 甲状腺:- 副腎:3.58 膵臓:4.20 乳腺:3.85 唾液腺:4.44
CAGE 子宮:0 胎盤:0 前立腺:0.20 卵巣:0 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0.42 結腸:0.93     肝臓:0    肺:0.75 膀胱:0.18 腎臓:- 下垂体:0 甲状腺:- 副腎:0.26 膵臓:0.84 乳腺:0.64 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.41 食道:- 胃:- 腸:- 結腸:-     肝臓:1.90        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_054039
Gene ID 20371
Unigene ID Mm.182291
Probe set ID 1420765_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000039521

オーソログ対応遺伝子

ヒト[2]  NM_001114377, NM_014009
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

IPR001766  Transcription factor, fork head
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

2053595
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0001782  B cell homeostasis
GO:0002361  CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0021549  cerebellum development
GO:0001816  cytokine production
GO:0009790  embryonic development
GO:0002262  myeloid cell homeostasis
GO:0008285  negative regulation of cell proliferation
GO:0002677  negative regulation of chronic inflammatory response
GO:0032792  negative regulation of CREB transcription factor activity
GO:0042036  negative regulation of cytokine biosynthetic process
GO:0050710  negative regulation of cytokine secretion
GO:0035067  negative regulation of histone acetylation
GO:0031064  negative regulation of histone deacetylation
GO:0050777  negative regulation of immune response
GO:0050728  negative regulation of inflammatory response
GO:0045077  negative regulation of interferon-gamma biosynthetic process
GO:0032689  negative regulation of interferon-gamma production
GO:0032693  negative regulation of interleukin-10 production
GO:0045085  negative regulation of interleukin-2 biosynthetic process
GO:0032703  negative regulation of interleukin-2 production
GO:0032713  negative regulation of interleukin-4 production
GO:0032714  negative regulation of interleukin-5 production
GO:0032715  negative regulation of interleukin-6 production
GO:0048294  negative regulation of isotype switching to IgE isotypes
GO:0050672  negative regulation of lymphocyte proliferation
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0002725  negative regulation of T cell cytokine production
GO:0042130  negative regulation of T cell proliferation
GO:0043433  negative regulation of transcription factor activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0032720  negative regulation of tumor necrosis factor production
GO:0007389  pattern specification process
GO:0032831  positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0010628  positive regulation of gene expression
GO:0035066  positive regulation of histone acetylation
GO:0033092  positive regulation of immature T cell proliferation in the thymus
GO:0032753  positive regulation of interleukin-4 production
GO:0002851  positive regulation of peripheral T cell tolerance induction
GO:0045591  positive regulation of regulatory T cell differentiation
GO:0002669  positive regulation of T cell anergy
GO:0002666  positive regulation of T cell tolerance induction
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0032914  positive regulation of transforming growth factor-beta1 production
GO:0009791  post-embryonic development
GO:0002637  regulation of immunoglobulin production
GO:0048302  regulation of isotype switching to IgG isotypes
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0045066  regulatory T cell differentiation
GO:0042110  T cell activation
GO:0002456  T cell mediated immunity
GO:0050852  T cell receptor signaling pathway
GO:0002507  tolerance induction
GO:0002513  tolerance induction to self antigen
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005622  intracellular
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0008301  DNA bending activity
GO:0003677  DNA binding
GO:0003690  double-stranded DNA binding
GO:0035035  histone acetyltransferase binding
GO:0042826  histone deacetylase binding
GO:0046872  metal ion binding
GO:0051525  NFAT protein binding
GO:0003676  nucleic acid binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity