secreted frizzled-related protein 1

詳細情報を見る

同義遺伝子名

Secreted frizzled-related protein 1 precursor, Sfrp1, AW107218, AW011917, 2210415K03Rik, AW742929, sFRP-1, secreted frizzled-related sequence protein 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:130.20 小脳:184.20 脳幹:63.60 脳梁:- 松果体:- 末梢神経:172 脊柱:189.10 網膜:32.10 目:235.50 動脈:168.80 静脈:- リンパ節:- 末梢血:- 脾臓:92.20 胸腺:158.10 骨髄:- 脂肪:- 骨:100.20 皮膚:95
GeneChip 大脳:5.70 小脳:5.32 脳幹:- 脳梁:- 松果体:- 末梢神経:6.79 脊柱:6.85 網膜:7.10 目:8.99 動脈:- 静脈:7.36 リンパ節:5.44 末梢血:- 脾臓:6.56 胸腺:- 骨髄:5.41 脂肪:6.75 骨:5.41 皮膚:7.83
CAGE 大脳:2.03 小脳:- 脳幹:2.59 脳梁:- 松果体:- 末梢神経:- 脊柱:3.35 網膜:- 目:- 動脈:4.29 静脈:- リンパ節:1.86 末梢血:- 脾臓:3.29 胸腺:3.52 骨髄:- 脂肪:- 骨:1.51 皮膚:4.53
RNA-seq 大脳:0.95 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:130.90 胎盤:- 前立腺:61.80 卵巣:46 精巣:66.50 心臓:55.80 骨格筋:- 食道:- 胃:163.60 腸:- 結腸:17.60     肝臓:-        肺:70.30    膀胱:66.20 腎臓:209.50 下垂体:51.70 甲状腺:- 副腎:- 膵臓:140.70 乳腺:55.50 唾液腺:-
GeneChip 子宮:6.07 胎盤:5.93 前立腺:6.30 卵巣:7.91 精巣:5.64 心臓:6.44 骨格筋:5.90 食道:- 胃:7.68 腸:7.04 結腸:- 肝臓:5.68 肺:6.19 膀胱:7.54 腎臓:9.04 下垂体:5.59 甲状腺:- 副腎:6.80 膵臓:5.93 乳腺:5.83 唾液腺:8.04
CAGE 子宮:2.59 胎盤:2.49 前立腺:2.52 卵巣:4.19 精巣:1.18 心臓:- 骨格筋:- 食道:- 胃:4.77 腸:3.41 結腸:3.78     肝臓:1.22    肺:2.78 膀胱:3.73 腎臓:- 下垂体:0.86 甲状腺:- 副腎:3.56 膵臓:2.56 乳腺:1.85 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.32 食道:- 胃:- 腸:- 結腸:-     肝臓:0.74        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0009952  anterior/posterior pattern formation
GO:0060346  bone trabecula formation
GO:0007420  brain development
GO:0030154  cell differentiation
GO:0071391  cellular response to estrogen stimulus
GO:0071363  cellular response to growth factor stimulus
GO:0071504  cellular response to heparin
GO:0071356  cellular response to tumor necrosis factor
GO:0071481  cellular response to X-ray
GO:0046546  development of primary male sexual characteristics
GO:0048546  digestive tract morphogenesis
GO:0006309  DNA fragmentation involved in apoptosis
GO:0009950  dorsal/ventral axis specification
GO:0008585  female gonad development
GO:0030097  hemopoiesis
GO:0002244  hemopoietic progenitor cell differentiation
GO:0060218  hemopoietic stem cell differentiation
GO:0008584  male gonad development
GO:0007275  multicellular organismal development
GO:0060766  negative regulation of androgen receptor signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0045578  negative regulation of B cell differentiation
GO:0030514  negative regulation of BMP signaling pathway
GO:0046851  negative regulation of bone remodeling
GO:0030308  negative regulation of cell growth
GO:0030336  negative regulation of cell migration
GO:0008285  negative regulation of cell proliferation
GO:0050680  negative regulation of epithelial cell proliferation
GO:0010719  negative regulation of epithelial to mesenchymal transition
GO:0048147  negative regulation of fibroblast proliferation
GO:0010629  negative regulation of gene expression
GO:0046676  negative regulation of insulin secretion
GO:0043508  negative regulation of JUN kinase activity
GO:0030279  negative regulation of ossification
GO:0045668  negative regulation of osteoblast differentiation
GO:0033689  negative regulation of osteoblast proliferation
GO:0045671  negative regulation of osteoclast differentiation
GO:0050732  negative regulation of peptidyl-tyrosine phosphorylation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0014034  neural crest cell fate commitment
GO:0001843  neural tube closure
GO:0021915  neural tube development
GO:0090179  planar cell polarity pathway involved in neural tube closure
GO:0043065  positive regulation of apoptosis
GO:0030307  positive regulation of cell growth
GO:0008284  positive regulation of cell proliferation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0045600  positive regulation of fat cell differentiation
GO:0045880  positive regulation of smoothened signaling pathway
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0060527  prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060687  regulation of branching involved in prostate gland morphogenesis
GO:0010564  regulation of cell cycle process
GO:0090175  regulation of establishment of planar polarity
GO:0030278  regulation of ossification
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0042493  response to drug
GO:0014070  response to organic cyclic substance
GO:0035019  somatic stem cell maintenance
GO:0001756  somitogenesis
GO:0034446  substrate adhesion-dependent cell spreading
GO:0001944  vasculature development
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin
GO:0060071  Wnt receptor signaling pathway, planar cell polarity pathway

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005622  intracellular
GO:0005886  plasma membrane
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0004197  cysteine-type endopeptidase activity
GO:0008144  drug binding
GO:0005109  frizzled binding
GO:0008201  heparin binding
GO:0042802  identical protein binding
GO:0030165  PDZ domain binding
GO:0042813  Wnt receptor activity
GO:0017147  Wnt-protein binding