secreted frizzled-related protein 1

同義遺伝子名

Secreted frizzled-related protein 1 precursor, Sfrp1, AW107218, AW011917, 2210415K03Rik, AW742929, sFRP-1, secreted frizzled-related sequence protein 1

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:130.20

小脳:184.20

脳幹:63.60

脳梁:-

松果体:-

末梢神経:172

脊柱:189.10

網膜:32.10

目:235.50

動脈:168.80

静脈:-

リンパ節:-

末梢血:-

脾臓:92.20

胸腺:158.10

骨髄:-

脂肪:-

骨:100.20

皮膚:95

GeneChip

大脳:5.70

小脳:5.32

脳幹:-

脳梁:-

松果体:-

末梢神経:6.79

脊柱:6.85

網膜:7.10

目:8.99

動脈:-

静脈:7.36

リンパ節:5.44

末梢血:-

脾臓:6.56

胸腺:-

骨髄:5.41

脂肪:6.75

骨:5.41

皮膚:7.83

CAGE

大脳:2.03

小脳:-

脳幹:2.59

脳梁:-

松果体:-

末梢神経:-

脊柱:3.35

網膜:-

目:-

動脈:4.29

静脈:-

リンパ節:1.86

末梢血:-

脾臓:3.29

胸腺:3.52

骨髄:-

脂肪:-

骨:1.51

皮膚:4.53

RNA-seq

大脳:0.95

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:130.90

胎盤:-

前立腺:61.80

卵巣:46

精巣:66.50

心臓:55.80

骨格筋:-

食道:-

胃:163.60

腸:-

結腸:17.60

肝臓:-

肺:70.30

膀胱:66.20

腎臓:209.50

下垂体:51.70

甲状腺:-

副腎:-

膵臓:140.70

乳腺:55.50

唾液腺:-

GeneChip

子宮:6.07

胎盤:5.93

前立腺:6.30

卵巣:7.91

精巣:5.64

心臓:6.44

骨格筋:5.90

食道:-

胃:7.68

腸:7.04

結腸:-

肝臓:5.68

肺:6.19

膀胱:7.54

腎臓:9.04

下垂体:5.59

甲状腺:-

副腎:6.80

膵臓:5.93

乳腺:5.83

唾液腺:8.04

CAGE

子宮:2.59

胎盤:2.49

前立腺:2.52

卵巣:4.19

精巣:1.18

心臓:-

骨格筋:-

食道:-

胃:4.77

腸:3.41

結腸:3.78

肝臓:1.22

肺:2.78

膀胱:3.73

腎臓:-

下垂体:0.86

甲状腺:-

副腎:3.56

膵臓:2.56

乳腺:1.85

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.32

食道:-

胃:-

腸:-

結腸:-

肝臓:0.74

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_013834
Gene ID	20377
Unigene ID	Mm.281691
Probe set ID	1448395_at [Mouse430_2]
Ensembl ID	ENSMUSG00000031548

オーソログ対応遺伝子

ヒト[3]	NM_003012
ラット[3]	NM_003012

染色体

遺伝子ファミリー (Interpro ID)

IPR020067	Frizzled-like domain
IPR001134	Netrin domain
IPR018933	Netrin module, non-TIMP type
IPR008993	TIMP-like, OB-fold

遺伝子オントロジー (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0009952	anterior/posterior pattern formation
GO:0060346	bone trabecula formation
GO:0007420	brain development
GO:0030154	cell differentiation
GO:0071391	cellular response to estrogen stimulus
GO:0071363	cellular response to growth factor stimulus
GO:0071504	cellular response to heparin
GO:0071356	cellular response to tumor necrosis factor
GO:0071481	cellular response to X-ray
GO:0046546	development of primary male sexual characteristics
GO:0048546	digestive tract morphogenesis
GO:0006309	DNA fragmentation involved in apoptosis
GO:0009950	dorsal/ventral axis specification
GO:0008585	female gonad development
GO:0030097	hemopoiesis
GO:0002244	hemopoietic progenitor cell differentiation
GO:0060218	hemopoietic stem cell differentiation
GO:0008584	male gonad development
GO:0007275	multicellular organismal development
GO:0060766	negative regulation of androgen receptor signaling pathway
GO:0043066	negative regulation of apoptosis
GO:0045578	negative regulation of B cell differentiation
GO:0030514	negative regulation of BMP signaling pathway
GO:0046851	negative regulation of bone remodeling
GO:0030308	negative regulation of cell growth
GO:0030336	negative regulation of cell migration
GO:0008285	negative regulation of cell proliferation
GO:0050680	negative regulation of epithelial cell proliferation
GO:0010719	negative regulation of epithelial to mesenchymal transition
GO:0048147	negative regulation of fibroblast proliferation
GO:0010629	negative regulation of gene expression
GO:0046676	negative regulation of insulin secretion
GO:0043508	negative regulation of JUN kinase activity
GO:0030279	negative regulation of ossification
GO:0045668	negative regulation of osteoblast differentiation
GO:0033689	negative regulation of osteoblast proliferation
GO:0045671	negative regulation of osteoclast differentiation
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0030178	negative regulation of Wnt receptor signaling pathway
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0014034	neural crest cell fate commitment
GO:0001843	neural tube closure
GO:0021915	neural tube development
GO:0090179	planar cell polarity pathway involved in neural tube closure
GO:0043065	positive regulation of apoptosis
GO:0030307	positive regulation of cell growth
GO:0008284	positive regulation of cell proliferation
GO:0050679	positive regulation of epithelial cell proliferation
GO:0045600	positive regulation of fat cell differentiation
GO:0045880	positive regulation of smoothened signaling pathway
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0030177	positive regulation of Wnt receptor signaling pathway
GO:0060527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060687	regulation of branching involved in prostate gland morphogenesis
GO:0010564	regulation of cell cycle process
GO:0090175	regulation of establishment of planar polarity
GO:0030278	regulation of ossification
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0042493	response to drug
GO:0014070	response to organic cyclic substance
GO:0035019	somatic stem cell maintenance
GO:0001756	somitogenesis
GO:0034446	substrate adhesion-dependent cell spreading
GO:0001944	vasculature development
GO:0016055	Wnt receptor signaling pathway
GO:0060070	Wnt receptor signaling pathway through beta-catenin
GO:0060071	Wnt receptor signaling pathway, planar cell polarity pathway

Cellular Component

GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0031012	extracellular matrix
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005622	intracellular
GO:0005886	plasma membrane
GO:0005578	proteinaceous extracellular matrix

Molecular Function

GO:0004197	cysteine-type endopeptidase activity
GO:0008144	drug binding
GO:0005109	frizzled binding
GO:0008201	heparin binding
GO:0042802	identical protein binding
GO:0030165	PDZ domain binding
GO:0042813	Wnt receptor activity
GO:0017147	Wnt-protein binding

secreted frizzled-related protein 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function