serine/threonine kinase 11

詳細情報を見る

同義遺伝子名

R75140, AA408040, Stk11, Lkb1, serine/threonine kinase 11

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:161.50 小脳:257.90 脳幹:222.50 脳梁:- 松果体:- 末梢神経:76.40 脊柱:472.90 網膜:160.70 目:76 動脈:- 静脈:- リンパ節:32.40 末梢血:287.50 脾臓:118.50 胸腺:79 骨髄:51.30 脂肪:- 骨:50.10 皮膚:55.40
GeneChip 大脳:8.50 小脳:8.88 脳幹:- 脳梁:- 松果体:- 末梢神経:8.64 脊柱:8.63 網膜:7.55 目:7.42 動脈:- 静脈:8.76 リンパ節:9.28 末梢血:- 脾臓:9.37 胸腺:- 骨髄:10.15 脂肪:9.15 骨:9.38 皮膚:8.80
CAGE 大脳:3.56 小脳:- 脳幹:3.57 脳梁:- 松果体:- 末梢神経:- 脊柱:3.49 網膜:- 目:- 動脈:3.60 静脈:- リンパ節:2.54 末梢血:- 脾臓:4.38 胸腺:3.74 骨髄:- 脂肪:- 骨:4.21 皮膚:3.50
RNA-seq 大脳:12.68 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:69 前立腺:- 卵巣:91.90 精巣:22.20 心臓:55.80 骨格筋:35.50 食道:- 胃:32.70 腸:- 結腸:52.90     肝臓:81.50        肺:110.50    膀胱:66.20 腎臓:32.20 下垂体:245.40 甲状腺:- 副腎:424.40 膵臓:9.40 乳腺:68.60 唾液腺:216
GeneChip 子宮:9.27 胎盤:8.90 前立腺:9.70 卵巣:9.20 精巣:9.71 心臓:9.02 骨格筋:9.78 食道:- 胃:9.24 腸:8.97 結腸:- 肝臓:9.31 肺:9.18 膀胱:8.91 腎臓:8.65 下垂体:9.25 甲状腺:- 副腎:9.15 膵臓:8.68 乳腺:9.29 唾液腺:9.80
CAGE 子宮:3.53 胎盤:3.67 前立腺:3.82 卵巣:3.56 精巣:5.28 心臓:- 骨格筋:- 食道:- 胃:3.48 腸:3.40 結腸:3.61     肝臓:4.13    肺:3.89 膀胱:3.54 腎臓:- 下垂体:3.78 甲状腺:- 副腎:3.76 膵臓:4.29 乳腺:3.80 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:21.46 食道:- 胃:- 腸:- 結腸:-     肝臓:10.66        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_011492
Gene ID 20869
Unigene ID Mm.135645
Probe set ID 1418644_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000003068

オーソログ対応遺伝子

ヒト[2]  NM_000455
ラット[1]  NM_001108069

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0032147  activation of protein kinase activity
GO:0043276  anoikis
GO:0006915  apoptosis
GO:0006914  autophagy
GO:0007409  axonogenesis
GO:0007049  cell cycle
GO:0007050  cell cycle arrest
GO:0030010  establishment of cell polarity
GO:0042593  glucose homeostasis
GO:0051645  Golgi localization
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0060770  negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0016310  phosphorylation
GO:0050772  positive regulation of axonogenesis
GO:0045722  positive regulation of gluconeogenesis
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0045860  positive regulation of protein kinase activity
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0045059  positive thymic T cell selection
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0051291  protein heterooligomerization
GO:0001558  regulation of cell growth
GO:0051896  regulation of protein kinase B signaling cascade
GO:0030111  regulation of Wnt receptor signaling pathway
GO:0006974  response to DNA damage stimulus
GO:0010212  response to ionizing radiation
GO:0033993  response to lipid
GO:0007286  spermatid development
GO:0050852  T cell receptor signaling pathway
GO:0001894  tissue homeostasis
GO:0001944  vasculature development
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0016020  membrane
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0005524  ATP binding
GO:0042802  identical protein binding
GO:0016301  kinase activity
GO:0030275  LRR domain binding
GO:0000287  magnesium ion binding
GO:0046872  metal ion binding
GO:0000166  nucleotide binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0030295  protein kinase activator activity
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups