histone deacetylase 4

詳細情報を見る

同義遺伝子名

4932408F19Rik, histone deacetylase 4, AI047285, Hdac4

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:46.90 小脳:110.50 脳幹:95.30 脳梁:- 松果体:- 末梢神経:38.20 脊柱:- 網膜:64.30 目:45.60 動脈:- 静脈:- リンパ節:183.60 末梢血:- 脾臓:13.20 胸腺:49.40 骨髄:12.80 脂肪:425.40 骨:37.60 皮膚:7.90
GeneChip nodata
CAGE 大脳:2.94 小脳:- 脳幹:2.77 脳梁:- 松果体:- 末梢神経:- 脊柱:2.87 網膜:- 目:- 動脈:2.38 静脈:- リンパ節:2.69 末梢血:- 脾臓:2.16 胸腺:2.59 骨髄:- 脂肪:- 骨:2.29 皮膚:3.02
RNA-seq 大脳:2.06 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:13.80 前立腺:- 卵巣:34.50 精巣:36.90 心臓:93 骨格筋:35.50 食道:- 胃:32.70 腸:- 結腸:-     肝臓:9.10        肺:40.20    膀胱:66.20 腎臓:40.30 下垂体:90.40 甲状腺:112.50 副腎:- 膵臓:46.90 乳腺:3.30 唾液腺:-
GeneChip nodata
CAGE 子宮:2.85 胎盤:3.07 前立腺:1.97 卵巣:2.98 精巣:2.79 心臓:- 骨格筋:- 食道:- 胃:0.67 腸:2.83 結腸:2.66     肝臓:2.20    肺:2.76 膀胱:2.98 腎臓:- 下垂体:2.83 甲状腺:- 副腎:3.20 膵臓:2.45 乳腺:2.31 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.25 食道:- 胃:- 腸:- 結腸:-     肝臓:1.63        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0016568  chromatin modification
GO:0006338  chromatin remodeling
GO:0016575  histone deacetylation
GO:0070932  histone H3 deacetylation
GO:0070933  histone H4 deacetylation
GO:0008285  negative regulation of cell proliferation
GO:0045820  negative regulation of glycolysis
GO:0010832  negative regulation of myotube differentiation
GO:0045668  negative regulation of osteoblast differentiation
GO:0043433  negative regulation of transcription factor activity
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0002076  osteoblast development
GO:0034983  peptidyl-lysine deacetylation
GO:0008284  positive regulation of cell proliferation
GO:0033235  positive regulation of protein sumoylation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006476  protein amino acid deacetylation
GO:0010882  regulation of cardiac muscle contraction by calcium ion signaling
GO:0043393  regulation of protein binding
GO:0048742  regulation of skeletal muscle fiber development
GO:0051153  regulation of striated muscle cell differentiation
GO:0006355  regulation of transcription, DNA-dependent
GO:0014894  response to denervation involved in regulation of muscle adaptation
GO:0042493  response to drug
GO:0070555  response to interleukin-1
GO:0001501  skeletal system development
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0031672  A band
GO:0042641  actomyosin
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0000118  histone deacetylase complex
GO:0031594  neuromuscular junction
GO:0005634  nucleus
GO:0043234  protein complex
GO:0030017  sarcomere
GO:0017053  transcriptional repressor complex
GO:0030018  Z disc

Molecular Function

GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0004407  histone deacetylase activity
GO:0031078  histone deacetylase activity (H3-K14 specific)
GO:0034739  histone deacetylase activity (H3-K16 specific)
GO:0032129  histone deacetylase activity (H3-K9 specific)
GO:0042826  histone deacetylase binding
GO:0016787  hydrolase activity
GO:0046872  metal ion binding
GO:0032041  NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969  NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970  NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0030955  potassium ion binding
GO:0005515  protein binding
GO:0033558  protein deacetylase activity
GO:0019901  protein kinase binding
GO:0043565  sequence-specific DNA binding
GO:0033613  transcription activator binding
GO:0003714  transcription corepressor activity
GO:0008134  transcription factor binding
GO:0070491  transcription repressor binding
GO:0008270  zinc ion binding