transcription factor 7-like 2, T-cell specific, HMG-box

同義遺伝子名

mTcf-4E, Transcription factor 7-like 2, mTcf-4B, Tcf7l2, TCF4E, Tcf-4, TCF4B, TCF-4, T-cell-specific transcription factor 4, mTCF-4, HMG box transcription factor 4

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:137.20

小脳:18.40

脳幹:444.90

脳梁:-

松果体:257.80

末梢神経:19.10

脊柱:-

網膜:32.10

目:38

動脈:337.60

静脈:-

リンパ節:54

末梢血:301.90

脾臓:-

胸腺:128.40

骨髄:12.80

脂肪:425.40

骨:37.60

皮膚:23.80

GeneChip

大脳:5.29

小脳:4.39

脳幹:-

脳梁:-

松果体:-

末梢神経:4.45

脊柱:4.73

網膜:5.35

目:5.44

動脈:-

静脈:7.08

リンパ節:5.77

末梢血:-

脾臓:6.11

胸腺:-

骨髄:5.37

脂肪:6.24

骨:6.01

皮膚:6.28

CAGE

大脳:3.11

小脳:-

脳幹:4.46

脳梁:-

松果体:-

末梢神経:-

脊柱:3.16

網膜:-

目:-

動脈:4.94

静脈:-

リンパ節:4.81

末梢血:-

脾臓:4.06

胸腺:3.18

骨髄:-

脂肪:-

骨:3.41

皮膚:5.18

RNA-seq

大脳:2.64

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:13.80

前立腺:30.90

卵巣:-

精巣:7.40

心臓:74.40

骨格筋:-

食道:-

胃:294.60

腸:-

結腸:105.70

肝臓:-

肺:100.40

膀胱:132.40

腎臓:72.50

下垂体:116.30

甲状腺:112.50

副腎:-

膵臓:187.60

乳腺:84.90

唾液腺:54

GeneChip

子宮:6.47

胎盤:5.91

前立腺:6.99

卵巣:7.04

精巣:4.04

心臓:5.49

骨格筋:5.51

食道:-

胃:7.28

腸:8.04

結腸:-

肝臓:6.79

肺:6.58

膀胱:6.33

腎臓:5.74

下垂体:5.39

甲状腺:-

副腎:6.30

膵臓:4.56

乳腺:7.32

唾液腺:5.71

CAGE

子宮:4.17

胎盤:4.23

前立腺:4.85

卵巣:4.53

精巣:3.31

心臓:-

骨格筋:-

食道:-

胃:4.42

腸:4.89

結腸:5.26

肝臓:4.35

肺:4.26

膀胱:4.45

腎臓:-

下垂体:3.71

甲状腺:-

副腎:3.84

膵臓:4.41

乳腺:5.99

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.12

食道:-

胃:-

腸:-

結腸:-

肝臓:2.81

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_001142919
Gene ID	21416
Unigene ID	Mm.139815
Probe set ID	1429428_at [Mouse430_2]
Ensembl ID	ENSMUSG00000024985

オーソログ対応遺伝子

ヒト[36]	NM_001146274, NM_001146283, NM_001146284, NM_001146285, NM_001146286, NM_001198525, NM_001198526, NM_001198527, NM_001198528, NM_001198529, NM_001198531, NM_030756
ラット [0]

染色体

19D2 [55,816,300 - 56,008,144]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000910	High mobility group, HMG1/HMG2
IPR009071	High mobility group, superfamily

遺伝子オントロジー (GO ID)

Biological Process

GO:0001568	blood vessel development
GO:0030282	bone mineralization
GO:0007050	cell cycle arrest
GO:0008283	cell proliferation
GO:0048557	embryonic digestive tract morphogenesis
GO:0030538	embryonic genitalia morphogenesis
GO:0048619	embryonic hindgut morphogenesis
GO:0060325	face morphogenesis
GO:0045444	fat cell differentiation
GO:0042593	glucose homeostasis
GO:0043570	maintenance of DNA repeat elements
GO:0048625	myoblast cell fate commitment
GO:0030514	negative regulation of BMP signaling pathway
GO:0045599	negative regulation of fat cell differentiation
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
GO:0046621	negative regulation of organ growth
GO:0043433	negative regulation of transcription factor activity
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0021915	neural tube development
GO:0042475	odontogenesis of dentine-containing tooth
GO:0014003	oligodendrocyte development
GO:0021983	pituitary gland development
GO:0043065	positive regulation of apoptosis
GO:0050679	positive regulation of epithelial cell proliferation
GO:0010909	positive regulation of heparan sulfate proteoglycan biosynthetic process
GO:0032024	positive regulation of insulin secretion
GO:0032092	positive regulation of protein binding
GO:0046827	positive regulation of protein export from nucleus
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0032350	regulation of hormone metabolic process
GO:0031641	regulation of myelination
GO:0048713	regulation of oligodendrocyte differentiation
GO:0048641	regulation of skeletal muscle tissue development
GO:0048660	regulation of smooth muscle cell proliferation
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-dependent
GO:0009749	response to glucose stimulus
GO:0032252	secretory granule localization
GO:0043588	skin development
GO:0035019	somatic stem cell maintenance
GO:0006351	transcription, DNA-dependent
GO:0016055	Wnt receptor signaling pathway
GO:0060070	Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0070369	beta-catenin-TCF7L2 complex
GO:0005829	cytosol
GO:0000790	nuclear chromatin
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0032993	protein-DNA complex
GO:0005667	transcription factor complex

Molecular Function

GO:0070016	armadillo repeat domain binding
GO:0008013	beta-catenin binding
GO:0003682	chromatin binding
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0045295	gamma-catenin binding
GO:0035257	nuclear hormone receptor binding
GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

transcription factor 7-like 2, T-cell specific, HMG-box

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function