transcription factor AP-2, alpha

詳細情報を見る

同義遺伝子名

transcription factor AP-2, alpha, Tfap2a, AP-2, Activator protein 2, Transcription factor AP-2 alpha, Ap2, Tcfap2a, Activating enhancer-binding protein 2 alpha, Ap-2 (a), AP2-alpha, Ap2tf, AP-2 alpha

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:15.60 小脳:36.80 脳幹:- 脳梁:- 松果体:- 末梢神経:38.20 脊柱:94.60 網膜:96.40 目:45.60 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:39.60
GeneChip 大脳:5.05 小脳:6.26 脳幹:- 脳梁:- 松果体:- 末梢神経:5.33 脊柱:5.03 網膜:8.23 目:8.67 動脈:- 静脈:6.74 リンパ節:5.09 末梢血:- 脾臓:5.18 胸腺:- 骨髄:4.98 脂肪:6.03 骨:5.34 皮膚:9.29
CAGE 大脳:1.48 小脳:- 脳幹:0.95 脳梁:- 松果体:- 末梢神経:- 脊柱:0.66 網膜:- 目:- 動脈:0.14 静脈:- リンパ節:0.42 末梢血:- 脾臓:0 胸腺:0.95 骨髄:- 脂肪:- 骨:0 皮膚:5.26
RNA-seq 大脳:9.55 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:55.20 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:50.20    膀胱:- 腎臓:- 下垂体:12.90 甲状腺:- 副腎:- 膵臓:- 乳腺:58.80 唾液腺:-
GeneChip 子宮:5.39 胎盤:6.36 前立腺:8.90 卵巣:5.09 精巣:5.25 心臓:5.55 骨格筋:5.06 食道:- 胃:5.72 腸:4.99 結腸:- 肝臓:5.32 肺:5.12 膀胱:5.44 腎臓:5.56 下垂体:5.06 甲状腺:- 副腎:5.10 膵臓:5.16 乳腺:6.90 唾液腺:8.77
CAGE 子宮:0.31 胎盤:2.82 前立腺:3.84 卵巣:0.35 精巣:0.45 心臓:- 骨格筋:- 食道:- 胃:2.66 腸:0 結腸:0.23     肝臓:0    肺:0.65 膀胱:1.73 腎臓:- 下垂体:0.29 甲状腺:- 副腎:0.14 膵臓:0 乳腺:3.92 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.71 食道:- 胃:- 腸:- 結腸:-     肝臓:0        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_001122948
Gene ID 21418
Unigene ID Mm.85544
Probe set ID 1421996_at  [Mouse430_2]
Ensembl ID ENSMUSG00000021359

オーソログ対応遺伝子

ヒト[6]  NM_001032280, NM_001042425, NM_003220
ラット[1]  NM_001107345, NM_001042425, NM_003220

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1295734
1989904
7477375
7525178
7555706
7615634
7729687
7750631
8233835
8622765
8622766
8692702
8808408
8824807
8885715
8989526
9006062
9271117
9284043
9353119
9463359
9758708
9765260
9811866
9858544
9918694
10068641
10079226
10079236
10349636
10529420
10571739
10588870
10625532
10655590
10662648
10803593
10842061
10932192
10946068
11042159
11076861
11118892
11137286
11217851
11319856
11406614
11518511
11522791
11553286
11598925
11688971
11694877
11741941
11744375
11784076
11940672
11967920
11969252
12062896
12223415
12223417
12438097
12466851
12477932
12504852
12514106
12522767
12586840
12654297
12694203
12711551
12749383
12839558
12878728
12960147
14572467
14623825
14651926
14969394
14975718
14975722
15013802
15063181
15070745
15136147
15148302
15181535
15198977
15328019
15475956
15489334
15581866
15618518
15663482
15680353
15936751
15996652
16024294
16102745
16141072
16141073
16186342
16207751
16221730
16368932
16399079
16449191
16672719
16836994
16839542
16887830
16894609
16919269
17042795
17067568
17107998
17344228
17428831
17442300
17519332
17670746
17676634
17679940
17724084
17728348
17984226
18224708
18243171
18287559
18330926
18334251
18424435
18594783
18653562
18723448
18816854
18824566
18832392
18832393
18836445
18987029
19000842
19141316
19198652
19376641
19387074
19420345
19463168
19474320
19509466
19557177
19558319
19570848
19666824
19685247
19692620
19700620
19700621
19705442
19749747
19750005
19782674
19842069
19855134
19943855
20016822
20035084
20059953
20071530
20079728
20110535
20122914
20144606
20150232
20171203
20175189
20211142
20215350
20351096
20412781
20457670
20459789
20459791
20500056
20501333
20525283
20529123
20660060
20807571
20847311
20932939
20962249
21070765
21138975
21157040
21177346
21233129
21246653
21256960
21303954
21364285
21377456
21394823
21539825
21543621
21600894
21829553
21858141
21978078
21982646
22020075
22040872
22083510
22110056
22116936
22138056
22215812
22240097
22274697
22275127
22411557
22451343
22484487
22503753
22609278
22848431
22966238
22972697
23044750
23112163
23126661
23201579
23292680
23351706
23393395
23437302
23592779
23595746
23690606
23907538
24068957
24086166
24140542
24198279
24336726
24374663
24451200

遺伝子オントロジー  (GO ID)

Biological Process

GO:0021506  anterior neuropore closure
GO:0060349  bone morphogenesis
GO:0071281  cellular response to iron ion
GO:0010172  embryonic body morphogenesis
GO:0048596  embryonic camera-type eye morphogenesis
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0035115  embryonic forelimb morphogenesis
GO:0009880  embryonic pattern specification
GO:0048730  epidermis morphogenesis
GO:0060325  face morphogenesis
GO:0021884  forebrain neuron development
GO:0035136  forelimb morphogenesis
GO:0042472  inner ear morphogenesis
GO:0003334  keratinocyte development
GO:0001822  kidney development
GO:0060235  lens induction in camera-type eye
GO:0002089  lens morphogenesis in camera-type eye
GO:0043066  negative regulation of apoptosis
GO:0008285  negative regulation of cell proliferation
GO:0042059  negative regulation of epidermal growth factor receptor signaling pathway
GO:0043524  negative regulation of neuron apoptosis
GO:0010944  negative regulation of transcription by competitive promoter binding
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0014032  neural crest cell development
GO:0001843  neural tube closure
GO:0021623  oculomotor nerve formation
GO:0003409  optic cup structural organization
GO:0003404  optic vesicle morphogenesis
GO:0003151  outflow tract morphogenesis
GO:0060021  palate development
GO:0030501  positive regulation of bone mineralization
GO:0030335  positive regulation of cell migration
GO:0010628  positive regulation of gene expression
GO:0043525  positive regulation of neuron apoptosis
GO:0070172  positive regulation of tooth mineralization
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0045595  regulation of cell differentiation
GO:0045664  regulation of neuron differentiation
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0032496  response to lipopolysaccharide
GO:0007605  sensory perception of sound
GO:0048705  skeletal system morphogenesis
GO:0043588  skin development
GO:0048485  sympathetic nervous system development
GO:0006366  transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0021559  trigeminal nerve development

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005794  Golgi apparatus
GO:0043231  intracellular membrane-bounded organelle
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0005515  protein binding
GO:0046983  protein dimerization activity
GO:0043565  sequence-specific DNA binding
GO:0003713  transcription coactivator activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding