arrestin, beta 2

詳細情報を見る

同義遺伝子名

beta-arrestin-2, beta arr2, AI326910, Arrestin beta 2, arrestin, beta 2, AW122872, Beta-arrestin-2, Arrb2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:46.90 小脳:- 脳幹:63.60 脳梁:- 松果体:- 末梢神経:114.70 脊柱:47.30 網膜:32.10 目:15.20 動脈:- 静脈:- リンパ節:356.40 末梢血:- 脾臓:79 胸腺:29.60 骨髄:102.60 脂肪:- 骨:187.90 皮膚:15.80
GeneChip 大脳:7.78 小脳:7.62 脳幹:- 脳梁:- 松果体:- 末梢神経:7.97 脊柱:7.79 網膜:6.37 目:6.44 動脈:- 静脈:6.96 リンパ節:9.67 末梢血:- 脾臓:9.76 胸腺:- 骨髄:10.59 脂肪:7.26 骨:10.10 皮膚:6.64
CAGE 大脳:3.57 小脳:- 脳幹:3.28 脳梁:- 松果体:- 末梢神経:- 脊柱:3.54 網膜:- 目:- 動脈:3.16 静脈:- リンパ節:4.86 末梢血:- 脾臓:4.13 胸腺:4.04 骨髄:- 脂肪:- 骨:4.99 皮膚:3.33
RNA-seq 大脳:7.49 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:13.80 前立腺:61.80 卵巣:- 精巣:7.40 心臓:18.60 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:18.10        肺:30.10    膀胱:132.40 腎臓:16.10 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:55.50 唾液腺:108
GeneChip 子宮:8.15 胎盤:6.10 前立腺:7.79 卵巣:7.40 精巣:6.01 心臓:6.63 骨格筋:7.06 食道:- 胃:6.80 腸:6.81 結腸:- 肝臓:7.23 肺:7.66 膀胱:6.64 腎臓:6.41 下垂体:7.21 甲状腺:- 副腎:7.66 膵臓:7.78 乳腺:7.20 唾液腺:7.50
CAGE 子宮:3.02 胎盤:1.95 前立腺:3.13 卵巣:2.89 精巣:1.89 心臓:- 骨格筋:- 食道:- 胃:3.42 腸:2.33 結腸:2.95     肝臓:3.13    肺:3.61 膀胱:2.79 腎臓:- 下垂体:2.53 甲状腺:- 副腎:3.17 膵臓:3.53 乳腺:2.73 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.99 食道:- 胃:- 腸:- 結腸:-     肝臓:2.59        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_145429
Gene ID 216869
Unigene ID Mm.203747
Probe set ID 1426239_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000060216

オーソログ対応遺伝子

ヒト[2]  NM_004313, NM_199004
ラット [0]  

染色体

-

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007628  adult walking behavior
GO:0060326  cell chemotaxis
GO:0002032  desensitization of G-protein coupled receptor protein signaling pathway by arrestin
GO:0050965  detection of temperature stimulus involved in sensory perception of pain
GO:0006309  DNA fragmentation involved in apoptosis
GO:0006897  endocytosis
GO:0042699  follicle-stimulating hormone signaling pathway
GO:0002031  G-protein coupled receptor internalization
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0034260  negative regulation of GTPase activity
GO:0032691  negative regulation of interleukin-1 beta production
GO:0032695  negative regulation of interleukin-12 production
GO:0032715  negative regulation of interleukin-6 production
GO:0045953  negative regulation of natural killer cell mediated cytotoxicity
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0031397  negative regulation of protein ubiquitination
GO:0009968  negative regulation of signal transduction
GO:0034392  negative regulation of smooth muscle cell apoptosis
GO:0034122  negative regulation of toll-like receptor signaling pathway
GO:0032720  negative regulation of tumor necrosis factor production
GO:0043065  positive regulation of apoptosis
GO:0051928  positive regulation of calcium ion transport
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0031398  positive regulation of protein ubiquitination
GO:0002092  positive regulation of receptor internalization
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0032226  positive regulation of synaptic transmission, dopaminergic
GO:0043161  proteasomal ubiquitin-dependent protein catabolic process
GO:0015031  protein transport
GO:0016567  protein ubiquitination
GO:0031623  receptor internalization
GO:0060765  regulation of androgen receptor signaling pathway
GO:0008277  regulation of G-protein coupled receptor protein signaling pathway
GO:0001932  regulation of protein amino acid phosphorylation
GO:0007165  signal transduction
GO:0006366  transcription from RNA polymerase II promoter
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0006810  transport

Cellular Component

GO:0016323  basolateral plasma membrane
GO:0005905  coated pit
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0043197  dendritic spine
GO:0005622  intracellular
GO:0016020  membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane

Molecular Function

GO:0031691  alpha-1A adrenergic receptor binding
GO:0031692  alpha-1B adrenergic receptor binding
GO:0031701  angiotensin receptor binding
GO:0031748  D1 dopamine receptor binding
GO:0031762  follicle stimulating hormone receptor binding
GO:0001664  G-protein-coupled receptor binding
GO:0051019  mitogen-activated protein kinase binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0032947  protein complex scaffold
GO:0019904  protein domain specific binding
GO:0043422  protein kinase B binding
GO:0005102  receptor binding
GO:0031702  type 1 angiotensin receptor binding
GO:0031826  type 2A serotonin receptor binding
GO:0031625  ubiquitin protein ligase binding