transforming growth factor, beta 2

詳細情報を見る

同義遺伝子名

Tgf-beta2, transforming growth factor, beta 2, Tgfb2, Transforming growth factor beta-2 precursor, Tgfb-2, TGF-beta-2, BB105277

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:41.70 小脳:257.90 脳幹:- 脳梁:- 松果体:257.80 末梢神経:133.80 脊柱:- 網膜:225 目:159.60 動脈:337.60 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:19.80 骨髄:- 脂肪:- 骨:50.10 皮膚:110.80
GeneChip 大脳:6.55 小脳:5.63 脳幹:- 脳梁:- 松果体:- 末梢神経:6.23 脊柱:6.49 網膜:7.67 目:9.20 動脈:- 静脈:10.01 リンパ節:4.75 末梢血:- 脾臓:4.76 胸腺:- 骨髄:4.27 脂肪:6.43 骨:6.13 皮膚:6.47
CAGE 大脳:3.33 小脳:- 脳幹:2.74 脳梁:- 松果体:- 末梢神経:- 脊柱:3.13 網膜:- 目:- 動脈:4.09 静脈:- リンパ節:1.86 末梢血:- 脾臓:0.71 胸腺:1.80 骨髄:- 脂肪:- 骨:2.66 皮膚:4.25
RNA-seq 大脳:1.47 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:87.20 胎盤:41.40 前立腺:30.90 卵巣:333.20 精巣:44.30 心臓:130.20 骨格筋:177.50 食道:- 胃:32.70 腸:- 結腸:-     肝臓:-        肺:100.40    膀胱:198.50 腎臓:40.30 下垂体:193.80 甲状腺:- 副腎:- 膵臓:56.30 乳腺:78.40 唾液腺:54
GeneChip 子宮:6.82 胎盤:9.13 前立腺:7.98 卵巣:6.96 精巣:4.43 心臓:6.83 骨格筋:7.67 食道:- 胃:5.57 腸:5.61 結腸:- 肝臓:4.57 肺:7.67 膀胱:8.80 腎臓:5.05 下垂体:5.49 甲状腺:- 副腎:5.22 膵臓:5.03 乳腺:7.70 唾液腺:8.81
CAGE 子宮:3.63 胎盤:5.10 前立腺:3.92 卵巣:3.24 精巣:0 心臓:- 骨格筋:- 食道:- 胃:2.79 腸:2.45 結腸:1.85     肝臓:1.12    肺:3.81 膀胱:4.24 腎臓:- 下垂体:1.86 甲状腺:- 副腎:1.92 膵臓:2.83 乳腺:4.05 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.61 食道:- 胃:- 腸:- 結腸:-     肝臓:0.62        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_009367
Gene ID 21808
Unigene ID Mm.18213
Probe set ID 1423250_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000039239

オーソログ対応遺伝子

ヒト[6]  NM_001135599, NM_003238
ラット[1]  NM_031131, NM_003238

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1284245
1373953
1375903
1543915
1577201
1638993
1672660
1676977
1707784
1723948
1764993
1879607
1955457
1970330
2015789
2040369
2226202
2375595
2401212
2481605
2797004
3226728
7485998
7493021
7574296
7601910
7627810
7687212
7774812
7813789
7819129
7819439
7842167
7883868
8002998
8050368
8075820
8119140
8125201
8148154
8164195
8206089
8358866
8530024
8541216
8565825
8726224
8916368
9010342
9169087
9177772
9184209
9203584
9217007
9427478
9525700
9768360
9839358
9921650
10030593
10349630
10349636
10433821
10446266
10521784
10588868
10725249
10848613
10922068
10976050
10984614
11042159
11076861
11084649
11092979
11106407
11109025
11159184
11180952
11217851
11390347
11404017
11526486
11675471
11677049
11784073
11829488
11830573
11850179
11854453
11857453
11882017
11934857
11960699
11984523
12091349
12114535
12141444
12142029
12192060
12217325
12220125
12381922
12393102
12466851
12477932
12478370
12588999
12617806
12666199
12666204
12773577
12805272
12815630
12838410
14550911
14701881
14707111
14973287
14985127
15031101
15206957
15226263
15248063
15294963
15305298
15342483
15478122
15528466
15531369
15582152
15615879
15630473
15724248
15744664
15896309
15911702
15923624
15929941
15963767
16026545
16026622
16141072
16141073
16192636
16257223
16282338
16314491
16466398
16598383
16602821
16632597
16702235
16741229
16787918
16879310
16887829
16919269
17141511
17272814
17303760
17325033
17350578
17391645
17418116
17460765
17519332
17526730
17559664
17634193
17673674
17767158
17804598
17881772
17997227
18159948
18213583
18287057
18287559
18317401
18358466
18498095
18498113
18508041
18723448
18790002
18796538
18804458
18854036
18941179
18945958
19084512
19109099
19123128
19141644
19161227
19164472
19304887
19403103
19449303
19465598
19509472
19587023
19757385
19846762
19906978
19965872
20007998
20184861
20200502
20230754
20299672
20300191
20346356
20421479
20427645
20501701
20530870
20565961
20603020
20633555
20858897
20875417
20890042
20970343
21087928
21181942
21266196
21300867
21352545
21356372
21436291
21512031
21533152
21593251
21597012
21780244
21880664
21909369
21959449
21967974
21983003
22130515
22186728
22235033
22326956
22331429
22437311
22485132
22560297
22573381
22674610
22682244
22696295
22739237
22772368
22847922
22899851
22995554
23041440
23193168
23303681
23319608
23342175
23525041
23560082
23584732
23603491
23824573
23946447
24045946
24161934
24356956
24449835
24623077

遺伝子オントロジー  (GO ID)

Biological Process

GO:0032147  activation of protein kinase activity
GO:0007411  axon guidance
GO:0001568  blood vessel development
GO:0001974  blood vessel remodeling
GO:0060317  cardiac epithelial to mesenchymal transition
GO:0003214  cardiac left ventricle morphogenesis
GO:0060038  cardiac muscle cell proliferation
GO:0003215  cardiac right ventricle morphogenesis
GO:0010002  cardioblast differentiation
GO:0001502  cartilage condensation
GO:0042637  catagen
GO:0007050  cell cycle arrest
GO:0008219  cell death
GO:0016049  cell growth
GO:0016477  cell migration
GO:0000902  cell morphogenesis
GO:0045216  cell-cell junction organization
GO:0030199  collagen fibril organization
GO:0042416  dopamine biosynthetic process
GO:0048702  embryonic neurocranium morphogenesis
GO:0001837  epithelial to mesenchymal transition
GO:0030198  extracellular matrix organization
GO:0001654  eye development
GO:0008347  glial cell migration
GO:0040007  growth
GO:0001942  hair follicle development
GO:0031069  hair follicle morphogenesis
GO:0007507  heart development
GO:0003007  heart morphogenesis
GO:0030097  hemopoiesis
GO:0010693  negative regulation of alkaline phosphatase activity
GO:0043066  negative regulation of apoptosis
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0050680  negative regulation of epithelial cell proliferation
GO:0050777  negative regulation of immune response
GO:0045617  negative regulation of keratinocyte differentiation
GO:0010936  negative regulation of macrophage cytokine production
GO:0051280  negative regulation of release of sequestered calcium ion into cytosol
GO:0048666  neuron development
GO:0048663  neuron fate commitment
GO:0003151  outflow tract morphogenesis
GO:0060389  pathway-restricted SMAD protein phosphorylation
GO:0070237  positive regulation of activation-induced cell death of T cells
GO:0043065  positive regulation of apoptosis
GO:0051891  positive regulation of cardioblast differentiation
GO:0051795  positive regulation of catagen
GO:0033630  positive regulation of cell adhesion mediated by integrin
GO:0045787  positive regulation of cell cycle
GO:0051781  positive regulation of cell division
GO:0030307  positive regulation of cell growth
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0010634  positive regulation of epithelial cell migration
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0010628  positive regulation of gene expression
GO:0045823  positive regulation of heart contraction
GO:0045726  positive regulation of integrin biosynthetic process
GO:0043525  positive regulation of neuron apoptosis
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0050714  positive regulation of protein secretion
GO:0032874  positive regulation of stress-activated MAPK cascade
GO:0006468  protein amino acid phosphorylation
GO:0042981  regulation of apoptosis
GO:0032909  regulation of transforming growth factor-beta2 production
GO:0042493  response to drug
GO:0043627  response to estrogen stimulus
GO:0001666  response to hypoxia
GO:0032570  response to progesterone stimulus
GO:0001501  skeletal system development
GO:0007184  SMAD protein nuclear translocation
GO:0048103  somatic stem cell division
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0060412  ventricular septum morphogenesis
GO:0042060  wound healing

Cellular Component

GO:0030424  axon
GO:0005604  basement membrane
GO:0043025  cell soma
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0030141  secretory granule
GO:0005802  trans-Golgi network

Molecular Function

GO:0001540  beta-amyloid binding
GO:0008083  growth factor activity
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0047485  protein N-terminus binding
GO:0005102  receptor binding
GO:0004702  receptor signaling protein serine/threonine kinase activity
GO:0005160  transforming growth factor beta receptor binding
GO:0005114  type II transforming growth factor beta receptor binding