transforming growth factor, beta receptor I

同義遺伝子名

TGF-beta receptor type-1 precursor, Alk-5, AU017191, TGF-beta type I receptor, Tgfbr1, TbetaRI, transforming growth factor, beta receptor I, TGF-beta receptor type I, ESK2, TGFR-1, ALK5, TbetaR-I

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:109.40

小脳:36.80

脳幹:-

脳梁:-

松果体:-

末梢神経:57.30

脊柱:-

網膜:128.60

目:174.80

動脈:84.40

静脈:-

リンパ節:194.40

末梢血:71.90

脾臓:79

胸腺:49.40

骨髄:-

脂肪:-

骨:62.60

皮膚:31.70

GeneChip

大脳:4.86

小脳:4.57

脳幹:-

脳梁:-

松果体:-

末梢神経:4.80

脊柱:4.83

網膜:4.31

目:4.55

動脈:-

静脈:7.43

リンパ節:6.18

末梢血:-

脾臓:5.99

胸腺:-

骨髄:5.76

脂肪:5.55

骨:5.37

皮膚:4.91

CAGE

大脳:1.69

小脳:-

脳幹:2.04

脳梁:-

松果体:-

末梢神経:-

脊柱:2.13

網膜:-

目:-

動脈:2.90

静脈:-

リンパ節:3.10

末梢血:-

脾臓:2.37

胸腺:3.11

骨髄:-

脂肪:-

骨:2.59

皮膚:2.39

RNA-seq

大脳:1.35

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:96.70

前立腺:61.80

卵巣:57.50

精巣:103.50

心臓:18.60

骨格筋:35.50

食道:-

胃:-

腸:37

結腸:35.20

肝臓:9.10

肺:50.20

膀胱:264.70

腎臓:64.50

下垂体:64.60

甲状腺:-

副腎:848.90

膵臓:75.10

乳腺:55.50

唾液腺:54

GeneChip

子宮:5.66

胎盤:5.92

前立腺:4.52

卵巣:6.36

精巣:8.36

心臓:4.83

骨格筋:5.12

食道:-

胃:5.29

腸:5.18

結腸:-

肝臓:5.64

肺:5.37

膀胱:6.38

腎臓:6.02

下垂体:5.52

甲状腺:-

副腎:4.88

膵臓:5.14

乳腺:5.45

唾液腺:4.63

CAGE

子宮:2.74

胎盤:2.44

前立腺:2.45

卵巣:3.31

精巣:2.60

心臓:-

骨格筋:-

食道:-

胃:2.16

腸:2.03

結腸:2.57

肝臓:2.53

肺:2.83

膀胱:3.13

腎臓:-

下垂体:2.81

甲状腺:-

副腎:3.19

膵臓:2.03

乳腺:2.61

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.67

食道:-

胃:-

腸:-

結腸:-

肝臓:3.40

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_009370
Gene ID	21812
Unigene ID	Mm.197552
Probe set ID	1420893_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000007613

オーソログ対応遺伝子

ヒト[2]	NM_001130916, NM_004612
ラット [0]

染色体

4B1 [47,366,094 - 47,427,803]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0000186	activation of MAPKK activity
GO:0001525	angiogenesis
GO:0009952	anterior/posterior pattern formation
GO:0006915	apoptosis
GO:0048844	artery morphogenesis
GO:0001824	blastocyst development
GO:0030154	cell differentiation
GO:0048870	cell motility
GO:0030199	collagen fibril organization
GO:0048701	embryonic cranial skeleton morphogenesis
GO:0009790	embryonic development
GO:0043542	endothelial cell migration
GO:0001837	epithelial to mesenchymal transition
GO:0008354	germ cell migration
GO:0007507	heart development
GO:0001701	in utero embryonic development
GO:0001822	kidney development
GO:0002088	lens development in camera-type eye
GO:0043066	negative regulation of apoptosis
GO:0032331	negative regulation of chondrocyte differentiation
GO:0045602	negative regulation of endothelial cell differentiation
GO:0001937	negative regulation of endothelial cell proliferation
GO:0048663	neuron fate commitment
GO:0060021	palate development
GO:0060017	parathyroid gland development
GO:0060389	pathway-restricted SMAD protein phosphorylation
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0060037	pharyngeal system development
GO:0016310	phosphorylation
GO:0030307	positive regulation of cell growth
GO:0008284	positive regulation of cell proliferation
GO:0051272	positive regulation of cellular component movement
GO:0051491	positive regulation of filopodium assembly
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0060391	positive regulation of SMAD protein nuclear translocation
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0009791	post-embryonic development
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0010468	regulation of gene expression
GO:0040008	regulation of growth
GO:0043393	regulation of protein binding
GO:0031396	regulation of protein ubiquitination
GO:0006355	regulation of transcription, DNA-dependent
GO:0070723	response to cholesterol
GO:0043627	response to estrogen stimulus
GO:0007165	signal transduction
GO:0001501	skeletal system development
GO:0048705	skeletal system morphogenesis
GO:0048538	thymus development
GO:0007179	transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0016324	apical plasma membrane
GO:0016323	basolateral plasma membrane
GO:0005901	caveola
GO:0030054	cell junction
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0045121	membrane raft
GO:0005886	plasma membrane
GO:0043234	protein complex
GO:0043235	receptor complex
GO:0005923	tight junction

Molecular Function

GO:0005524	ATP binding
GO:0019838	growth factor binding
GO:0070411	I-SMAD binding
GO:0016301	kinase activity
GO:0046872	metal ion binding
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0032403	protein complex binding
GO:0046982	protein heterodimerization activity
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0046332	SMAD binding
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0050431	transforming growth factor beta binding
GO:0005024	transforming growth factor beta receptor activity
GO:0005025	transforming growth factor beta receptor activity, type I
GO:0004675	transmembrane receptor protein serine/threonine kinase activity
GO:0005114	type II transforming growth factor beta receptor binding
GO:0031625	ubiquitin protein ligase binding

transforming growth factor, beta receptor I

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function