thrombospondin 1

詳細情報を見る

同義遺伝子名

Thrombospondin-1 precursor, Thbs-1, Tsp1, thrombospondin 1, TSP1, tbsp1, TSP-1, Thbs1

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:104.20

小脳:36.80

脳幹:127.10

脳梁:-

松果体:-

末梢神経:133.80

脊柱:94.60

網膜:64.30

目:45.60

動脈:-

静脈:-

リンパ節:10.80

末梢血:172.50

脾臓:92.20

胸腺:59.30

骨髄:-

脂肪:-

骨:25

皮膚:102.90

GeneChip

大脳:4.59

小脳:4.86

脳幹:-

脳梁:-

松果体:-

末梢神経:5.19

脊柱:4.72

網膜:6.37

目:5.59

動脈:-

静脈:8.42

リンパ節:5.77

末梢血:-

脾臓:6.54

胸腺:-

骨髄:9.87

脂肪:5.99

骨:9.61

皮膚:6.11

CAGE

大脳:1.63

小脳:-

脳幹:1.75

脳梁:-

松果体:-

末梢神経:-

脊柱:2.06

網膜:-

目:-

動脈:4.65

静脈:-

リンパ節:4.62

末梢血:-

脾臓:4.76

胸腺:2.03

骨髄:-

脂肪:-

骨:5.92

皮膚:4.75

RNA-seq

大脳:0.78

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:13.80

前立腺:-

卵巣:23

精巣:7.40

心臓:55.80

骨格筋:177.50

食道:-

胃:65.50

腸:-

結腸:70.50

肝臓:126.70

肺:20.10

膀胱:66.20

腎臓:32.20

下垂体:38.80

甲状腺:-

副腎:-

膵臓:84.40

乳腺:52.20

唾液腺:-

GeneChip

子宮:8.68

胎盤:7.49

前立腺:6.91

卵巣:9.04

精巣:4.95

心臓:6.46

骨格筋:5.68

食道:-

胃:6.71

腸:7.02

結腸:-

肝臓:4.97

肺:8.88

膀胱:8.69

腎臓:7.05

下垂体:4.93

甲状腺:-

副腎:5.06

膵臓:6

乳腺:7.77

唾液腺:9.09

CAGE

子宮:5.21

胎盤:4.02

前立腺:4.01

卵巣:5.88

精巣:1.48

心臓:-

骨格筋:-

食道:-

胃:3.17

腸:3.50

結腸:3.70

肝臓:1.22

肺:5.25

膀胱:4.81

腎臓:-

下垂体:3.20

甲状腺:-

副腎:3.44

膵臓:3.32

乳腺:3.82

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.52

食道:-

胃:-

腸:-

結腸:-

肝臓:1.85

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_011580
Gene ID	21825
Unigene ID	Mm.41593
Probe set ID	1450377_at [Mouse430_2]
Ensembl ID	ENSMUSG00000040152

オーソログ対応遺伝子

ヒト[4]	NM_003246
ラット[4]	NM_003246

染色体

遺伝子ファミリー (Interpro ID)

IPR001881	EGF-like calcium-binding
IPR000742	EGF-like, type 3
IPR000884	Thrombospondin, type 1 repeat

遺伝子オントロジー (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0048514	blood vessel morphogenesis
GO:0007155	cell adhesion
GO:0007050	cell cycle arrest
GO:0016477	cell migration
GO:0003197	endocardial cushion development
GO:0043652	engulfment of apoptotic cell
GO:0003417	growth plate cartilage development
GO:0006954	inflammatory response
GO:0016525	negative regulation of angiogenesis
GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0043066	negative regulation of apoptosis
GO:0043537	negative regulation of blood vessel endothelial cell migration
GO:0043154	negative regulation of caspase activity
GO:0001953	negative regulation of cell-matrix adhesion
GO:0010754	negative regulation of cGMP-mediated signaling
GO:0002605	negative regulation of dendritic cell antigen processing and presentation
GO:0010596	negative regulation of endothelial cell migration
GO:0001937	negative regulation of endothelial cell proliferation
GO:0051918	negative regulation of fibrinolysis
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
GO:0032695	negative regulation of interleukin-12 production
GO:0010751	negative regulation of nitric oxide mediated signal transduction
GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport
GO:0010757	negative regulation of plasminogen activation
GO:0003151	outflow tract morphogenesis
GO:0018149	peptide cross-linking
GO:0045766	positive regulation of angiogenesis
GO:0030194	positive regulation of blood coagulation
GO:0043536	positive regulation of blood vessel endothelial cell migration
GO:0030335	positive regulation of cell migration
GO:0010811	positive regulation of cell-substrate adhesion
GO:0050921	positive regulation of chemotaxis
GO:0010595	positive regulation of endothelial cell migration
GO:0010763	positive regulation of fibroblast migration
GO:0043032	positive regulation of macrophage activation
GO:0010759	positive regulation of macrophage chemotaxis
GO:0042327	positive regulation of phosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway
GO:0045727	positive regulation of translation
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
GO:0051592	response to calcium ion
GO:0009749	response to glucose stimulus
GO:0032026	response to magnesium ion
GO:0002040	sprouting angiogenesis

Cellular Component

GO:0009986	cell surface
GO:0009897	external side of plasma membrane
GO:0031012	extracellular matrix
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0070062	extracellular vesicular exosome
GO:0005577	fibrinogen complex
GO:0031091	platelet alpha granule
GO:0030141	secretory granule

Molecular Function

GO:0005509	calcium ion binding
GO:0070052	collagen V binding
GO:0050840	extracellular matrix binding
GO:0070051	fibrinogen binding
GO:0017134	fibroblast growth factor binding
GO:0001968	fibronectin binding
GO:0008201	heparin binding
GO:0005178	integrin binding
GO:0043236	laminin binding
GO:0030169	low-density lipoprotein binding
GO:0001786	phosphatidylserine binding

thrombospondin 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function