thyroid hormone receptor alpha

詳細情報を見る

同義遺伝子名

c-erbA-1, TR alpha 2, 6430529J03Rik, c-erbAalpha, T3Ralpha, Thra1, Rvr, Thyroid hormone receptor alpha, thyroid hormone receptor alpha, T3R[a], C-erba-alpha, TR alpha 1, Erba, Thra2, AW259572, Thra, Nr1a1, C-erbA-alpha

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:6.90 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:12.50 皮膚:7.90
GeneChip 大脳:8.55 小脳:8.43 脳幹:- 脳梁:- 松果体:- 末梢神経:7.65 脊柱:8.10 網膜:7.06 目:7.35 動脈:- 静脈:7.87 リンパ節:6.93 末梢血:- 脾臓:6.61 胸腺:- 骨髄:7.07 脂肪:7.82 骨:7.07 皮膚:8
CAGE 大脳:5.57 小脳:- 脳幹:5.29 脳梁:- 松果体:- 末梢神経:- 脊柱:5.01 網膜:- 目:- 動脈:4.41 静脈:- リンパ節:2.33 末梢血:- 脾臓:2.60 胸腺:2.68 骨髄:- 脂肪:- 骨:3.25 皮膚:4.35
RNA-seq 大脳:122.53 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:-        肺:10    膀胱:66.20 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:3.30 唾液腺:-
GeneChip 子宮:7.68 胎盤:6.82 前立腺:7.30 卵巣:7.77 精巣:6.64 心臓:8.40 骨格筋:8.27 食道:- 胃:7.91 腸:7.83 結腸:- 肝臓:6.68 肺:8.22 膀胱:7.65 腎臓:7.36 下垂体:7.34 甲状腺:- 副腎:7.36 膵臓:7.77 乳腺:7.68 唾液腺:7.75
CAGE 子宮:3.78 胎盤:2.40 前立腺:3.16 卵巣:3.97 精巣:2.12 心臓:- 骨格筋:- 食道:- 胃:3.80 腸:3.57 結腸:4.19     肝臓:1.94    肺:4.08 膀胱:4.29 腎臓:- 下垂体:4.29 甲状腺:- 副腎:3.88 膵臓:3.86 乳腺:3.11 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:10.84 食道:- 胃:- 腸:- 結腸:-     肝臓:9.90        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_178060
Gene ID 21833
Unigene ID Mm.442648
Probe set ID 1426997_at  [Mouse430_2]
Ensembl ID ENSMUSG00000058756

オーソログ対応遺伝子

ヒト[6]  NM_001190918, NM_001190919, NM_003250, NM_199334
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1225760
1302014
1352161
1427919
1676978
1679528
1794055
1850510
1889803
1889815
1944303
2162045
2286379
2349106
2539258
2567264
2851124
2879243
3116273
3399404
3416641
3629259
5309548
6087351
6328658
6594688
6690234
7507509
7557995
7566114
7613042
7613043
7760812
7769664
7838156
7838158
7935490
7956352
8103600
8251184
8389625
8439732
8449498
8507984
8559662
8595891
8889548
8910392
9177778
9250685
9259319
9337410
9372952
9430637
9620453
9859898
9861043
9927422
10337632
10346821
10348820
10349636
10362681
10430610
10605006
10681503
10691312
10712278
10769387
10848522
10922068
11042159
11075809
11076861
11113349
11120878
11138006
11159823
11180952
11217851
11222741
11222747
11259580
11416150
11416151
11481455
11496110
11572786
11641275
11725045
11726557
11731612
11731613
11734632
11739587
11773436
11786385
11843482
11867729
11891331
11940593
12039959
12054736
12072400
12127686
12145333
12150932
12169435
12198244
12356724
12388168
12438746
12456652
12466851
12477932
12556906
12562961
12576486
12581880
12591179
12591240
12677005
12750454
12776178
12782404
12845557
12869545
12888625
12933686
14610273
14627645
14630717
14630998
14681479
14726446
14729678
15062575
15180993
15240882
15304375
15322135
15340084
15374821
15601836
15618518
15673575
15713690
15780976
15782199
15802493
15808842
15845618
15858214
16051666
16131613
16141072
16141073
16150908
16322094
16571082
16579977
16581794
16602821
16648291
16803873
16902998
16919471
17065405
17122078
17129617
17210747
17220280
17317766
17327419
17488972
17520268
17601882
17622582
17872380
17932484
17952069
18203951
18287507
18287559
18575627
18641393
18795907
18799693
19001373
19074585
19094093
19114539
19131509
19244534
19282388
19462004
19477936
19549593
19782026
20059953
20062085
20080985
20090848
20114049
20153760
20159955
20160073
20194731
20228172
20412781
20529852
20566868
20580649
20709911
20726222
20739404
20932939
21292823
21344381
21389087
21566120
21621530
21652727
21677750
21858227
21914860
22001906
22109994
22147010
22253431
22322976
22361821
22392896
22468949
22509275
22539677
22570333
22891348
22930759
23161871
23341629
23493375
23567476
23595988
23610395
24012852
24040148
24098680
24346699
24381310
24395638

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001502  cartilage condensation
GO:0042994  cytoplasmic sequestering of transcription factor
GO:0030218  erythrocyte differentiation
GO:0008050  female courtship behavior
GO:0009755  hormone-mediated signaling pathway
GO:0030522  intracellular receptor-mediated signaling pathway
GO:0007611  learning or memory
GO:0017055  negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0043433  negative regulation of transcription factor activity
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0009887  organ morphogenesis
GO:0001503  ossification
GO:0045925  positive regulation of female receptivity
GO:0010831  positive regulation of myotube differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0008016  regulation of heart contraction
GO:0050994  regulation of lipid catabolic process
GO:0033032  regulation of myeloid cell apoptosis
GO:0002155  regulation of thyroid hormone mediated signaling pathway
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0009409  response to cold
GO:0043401  steroid hormone mediated signaling pathway
GO:0030878  thyroid gland development
GO:0006366  transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0060509  Type I pneumocyte differentiation

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005739  mitochondrion
GO:0005634  nucleus

Molecular Function

GO:0031490  chromatin DNA binding
GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0044213  intronic regulatory region binding
GO:0004879  ligand-dependent nuclear receptor activity
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0046983  protein dimerization activity
GO:0019904  protein domain specific binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0043565  sequence-specific DNA binding
GO:0003727  single-stranded RNA binding
GO:0003707  steroid hormone receptor activity
GO:0002153  steroid receptor RNA activator RNA binding
GO:0017025  TATA-binding protein binding
GO:0070324  thyroid hormone binding
GO:0004887  thyroid hormone receptor activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding
GO:0008270  zinc ion binding