NK2 homeobox 1

詳細情報を見る

同義遺伝子名

T/EBP, Homeobox protein Nkx-2.1, AV026640, Titf1, Nkx2.1, TTF-1, Thyroid transcription factor 1, thyroid-specific enhancer-binding protein, Ttf1, thyroid transcription factor 1, Thyroid nuclear factor 1, Nkx2-1, Nkx-2.1, Ttf-1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:6.90 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:4.65 小脳:4.59 脳幹:- 脳梁:- 松果体:- 末梢神経:4.84 脊柱:4.68 網膜:4.57 目:4.67 動脈:- 静脈:4.51 リンパ節:4.39 末梢血:- 脾臓:4.48 胸腺:- 骨髄:4.77 脂肪:4.57 骨:4.40 皮膚:4.51
CAGE 大脳:0 小脳:- 脳幹:0.30 脳梁:- 松果体:- 末梢神経:- 脊柱:0 網膜:- 目:- 動脈:0.14 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:0 骨髄:- 脂肪:- 骨:0 皮膚:0
RNA-seq 大脳:1.28 小脳:1.28 脳幹:1.28 脳梁:1.28 松果体:1.28 末梢神経:1.28 脊柱:1.28 網膜:1.28 目:1.28 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:80.30    膀胱:- 腎臓:- 下垂体:12.90 甲状腺:224.90 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:4.49 胎盤:4.66 前立腺:4.56 卵巣:4.37 精巣:4.97 心臓:4.79 骨格筋:4.75 食道:- 胃:4.63 腸:4.70 結腸:- 肝臓:5.47 肺:5.95 膀胱:4.52 腎臓:4.80 下垂体:4.84 甲状腺:- 副腎:4.29 膵臓:4.82 乳腺:4.37 唾液腺:4.60
CAGE 子宮:0 胎盤:0 前立腺:0 卵巣:0 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0 腸:0.23 結腸:0     肝臓:0    肺:5.04 膀胱:0 腎臓:- 下垂体:0.86 甲状腺:- 副腎:0 膵臓:0 乳腺:0 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_009385
Gene ID 21869
Unigene ID Mm.89972
Probe set ID 1422346_at  [Mouse430_2]
Ensembl ID ENSMUSG00000001496

オーソログ対応遺伝子

ヒト[4]  NM_001079668, NM_003317
ラット[2]  NM_013093, NM_003317

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1346742
1976511
2573058
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0048646  anatomical structure formation involved in morphogenesis
GO:0007411  axon guidance
GO:0007420  brain development
GO:0021795  cerebral cortex cell migration
GO:0021892  cerebral cortex GABAergic interneuron differentiation
GO:0021895  cerebral cortex neuron differentiation
GO:0060486  Clara cell differentiation
GO:0031128  developmental induction
GO:0007492  endoderm development
GO:0007631  feeding behavior
GO:0021798  forebrain dorsal/ventral pattern formation
GO:0021879  forebrain neuron differentiation
GO:0021877  forebrain neuron fate commitment
GO:0021759  globus pallidus development
GO:0021766  hippocampus development
GO:0042538  hyperosmotic salinity response
GO:0033327  Leydig cell differentiation
GO:0007626  locomotory behavior
GO:0030324  lung development
GO:0060430  lung saccule development
GO:0042696  menarche
GO:0030336  negative regulation of cell migration
GO:0010719  negative regulation of epithelial to mesenchymal transition
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0030512  negative regulation of transforming growth factor beta receptor signaling pathway
GO:0048663  neuron fate commitment
GO:0001764  neuron migration
GO:0048709  oligodendrocyte differentiation
GO:0009887  organ morphogenesis
GO:0007389  pattern specification process
GO:0006644  phospholipid metabolic process
GO:0021983  pituitary gland development
GO:0010628  positive regulation of gene expression
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0002016  regulation of blood volume by renin-angiotensin
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0006355  regulation of transcription, DNA-dependent
GO:0032496  response to lipopolysaccharide
GO:0022029  telencephalon cell migration
GO:0021537  telencephalon development
GO:0030878  thyroid gland development
GO:0006351  transcription, DNA-dependent
GO:0060510  Type II pneumocyte differentiation

Cellular Component

GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0005515  protein binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding