tumor necrosis factor, alpha-induced protein 3

詳細情報を見る

同義遺伝子名

Tnfaip3, A20, tumor necrosis factor, alpha-induced protein 3, Tumor necrosis factor, alpha-induced protein 3, Tnfip3, Putative DNA-binding protein A20, Zinc finger protein A20, zinc finger protein A20

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:10.40 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:19.10 脊柱:- 網膜:32.10 目:106.40 動脈:168.80 静脈:- リンパ節:421.30 末梢血:1351.40 脾臓:2554.30 胸腺:98.80 骨髄:320.50 脂肪:212.70 骨:125.20 皮膚:23.80
GeneChip nodata
CAGE 大脳:0.94 小脳:- 脳幹:0.89 脳梁:- 松果体:- 末梢神経:- 脊柱:0.91 網膜:- 目:- 動脈:1.94 静脈:- リンパ節:4.28 末梢血:- 脾臓:3.02 胸腺:3.85 骨髄:- 脂肪:- 骨:2.37 皮膚:2.58
RNA-seq 大脳:1.46 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:55.20 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:71 食道:- 胃:- 腸:- 結腸:-     肝臓:9.10        肺:20.10    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:18.80 乳腺:26.10 唾液腺:-
GeneChip nodata
CAGE 子宮:2.82 胎盤:2.00 前立腺:1.69 卵巣:1.42 精巣:0.75 心臓:- 骨格筋:- 食道:- 胃:1.57 腸:2.33 結腸:2.82     肝臓:1.38    肺:2.89 膀胱:1.69 腎臓:- 下垂体:1.69 甲状腺:- 副腎:1.85 膵臓:2.03 乳腺:2.11 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.04 食道:- 胃:- 腸:- 結腸:-     肝臓:1.68        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0001922  B-1 B cell homeostasis
GO:0070301  cellular response to hydrogen peroxide
GO:0071222  cellular response to lipopolysaccharide
GO:0006954  inflammatory response
GO:0002315  marginal zone B cell differentiation
GO:0008152  metabolic process
GO:0010507  negative regulation of autophagy
GO:0050869  negative regulation of B cell activation
GO:0060548  negative regulation of cell death
GO:0002677  negative regulation of chronic inflammatory response
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0002632  negative regulation of granuloma formation
GO:0034115  negative regulation of heterotypic cell-cell adhesion
GO:0043124  negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050728  negative regulation of inflammatory response
GO:0045824  negative regulation of innate immune response
GO:0032691  negative regulation of interleukin-1 beta production
GO:0032703  negative regulation of interleukin-2 production
GO:0032715  negative regulation of interleukin-6 production
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0070429  negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070433  negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0031397  negative regulation of protein ubiquitination
GO:0048662  negative regulation of smooth muscle cell proliferation
GO:0034140  negative regulation of toll-like receptor 3 signaling pathway
GO:0034148  negative regulation of toll-like receptor 5 signaling pathway
GO:0032720  negative regulation of tumor necrosis factor production
GO:0045732  positive regulation of protein catabolic process
GO:0016579  protein deubiquitination
GO:0070936  protein K48-linked ubiquitination
GO:0070536  protein K63-linked deubiquitination
GO:0006508  proteolysis
GO:0002634  regulation of germinal center formation
GO:0002637  regulation of immunoglobulin production
GO:0045088  regulation of innate immune response
GO:0002237  response to molecule of bacterial origin
GO:0032495  response to muramyl dipeptide
GO:0009611  response to wounding

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005764  lysosome
GO:0005634  nucleus

Molecular Function

GO:0003824  catalytic activity
GO:0008234  cysteine-type peptidase activity
GO:0003677  DNA binding
GO:0016787  hydrolase activity
GO:0019900  kinase binding
GO:0016874  ligase activity
GO:0046872  metal ion binding
GO:0008233  peptidase activity
GO:0002020  protease binding
GO:0005515  protein binding
GO:0043621  protein self-association
GO:0043130  ubiquitin binding
GO:0004221  ubiquitin thiolesterase activity
GO:0004842  ubiquitin-protein ligase activity
GO:0004843  ubiquitin-specific protease activity
GO:0008270  zinc ion binding