tumor necrosis factor (ligand) superfamily, member 11

同義遺伝子名

Opgl, RANKL, Tnfsf11, CD254 antigen, Ly109l, Rankl, Trance, Osteoprotegerin ligand, Tumor necrosis factor ligand superfamily member 11, osteoclast differentiation factor, OPG, ODF, Osteoclast differentiation factor, TNF-related activation-induced cytokine, OPGL, TRANCE

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:-

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:337.60

静脈:-

リンパ節:-

末梢血:-

脾臓:39.50

胸腺:49.40

骨髄:-

脂肪:-

骨:62.60

皮膚:-

GeneChip

大脳:4.21

小脳:4.40

脳幹:-

脳梁:-

松果体:-

末梢神経:4.21

脊柱:4.37

網膜:4.48

目:4.90

動脈:-

静脈:4.31

リンパ節:6.26

末梢血:-

脾臓:4.91

胸腺:-

骨髄:4.69

脂肪:4.50

骨:4.70

皮膚:4.48

CAGE

大脳:0

小脳:-

脳幹:0

脳梁:-

松果体:-

末梢神経:-

脊柱:0

網膜:-

目:-

動脈:0.14

静脈:-

リンパ節:2.64

末梢血:-

脾臓:0.62

胸腺:1.35

骨髄:-

脂肪:-

骨:1.02

皮膚:0.15

RNA-seq

nodata

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:4.21

胎盤:4.51

前立腺:4.41

卵巣:4.31

精巣:4.35

心臓:4.52

骨格筋:4.70

食道:-

胃:4.35

腸:4.34

結腸:-

肝臓:4.24

肺:4.42

膀胱:4.23

腎臓:4.48

下垂体:4.19

甲状腺:-

副腎:4.19

膵臓:4.49

乳腺:5.13

唾液腺:4.23

CAGE

子宮:0

胎盤:0

前立腺:0

卵巣:0.13

精巣:0.45

心臓:-

骨格筋:-

食道:-

胃:0

腸:0

結腸:0.23

肝臓:0

肺:0.17

膀胱:0.77

腎臓:-

下垂体:0

甲状腺:-

副腎:0

膵臓:0

乳腺:0.12

唾液腺:-

RNA-seq

nodata

IDs

Refseq ID	NM_011613
Gene ID	21943
Unigene ID	Mm.249221
Probe set ID	1451944_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000022015

オーソログ対応遺伝子

ヒト[4]	NM_003701, NM_033012
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR006052	Tumor Necrosis Factor
IPR008983	Tumour necrosis factor-like

遺伝子オントロジー (GO ID)

Biological Process

GO:0007257	activation of JUN kinase activity
GO:0045453	bone resorption
GO:0055074	calcium ion homeostasis
GO:0030154	cell differentiation
GO:0019221	cytokine-mediated signaling pathway
GO:0070371	ERK1 and ERK2 cascade
GO:0006955	immune response
GO:0048535	lymph node development
GO:0060749	mammary gland alveolus development
GO:0033598	mammary gland epithelial cell proliferation
GO:0002548	monocyte chemotaxis
GO:0007275	multicellular organismal development
GO:0009887	organ morphogenesis
GO:0001503	ossification
GO:0030316	osteoclast differentiation
GO:0045780	positive regulation of bone resorption
GO:0051466	positive regulation of corticotropin-releasing hormone secretion
GO:0034112	positive regulation of homotypic cell-cell adhesion
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0046330	positive regulation of JNK cascade
GO:0043406	positive regulation of MAP kinase activity
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0045672	positive regulation of osteoclast differentiation
GO:0042327	positive regulation of phosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0010740	positive regulation of protein kinase cascade
GO:0050870	positive regulation of T cell activation
GO:0051091	positive regulation of transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051260	protein homooligomerization
GO:0045670	regulation of osteoclast differentiation
GO:0033209	tumor necrosis factor-mediated signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0016021	integral to membrane
GO:0005622	intracellular
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0005125	cytokine activity
GO:0005515	protein binding
GO:0005164	tumor necrosis factor receptor binding
GO:0032813	tumor necrosis factor receptor superfamily binding

tumor necrosis factor (ligand) superfamily, member 11

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function