TNF receptor-associated factor 6

詳細情報を見る

同義遺伝子名

TNF receptor-associated factor 6, 2310003F17Rik, AI851288, Tnf receptor-associated factor 6, C630032O20Rik, Traf6

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:27.80 小脳:36.80 脳幹:- 脳梁:- 松果体:- 末梢神経:76.40 脊柱:- 網膜:32.10 目:98.80 動脈:168.80 静脈:- リンパ節:86.40 末梢血:115 脾臓:13.20 胸腺:88.90 骨髄:115.40 脂肪:- 骨:- 皮膚:7.90
GeneChip nodata
CAGE 大脳:2.04 小脳:- 脳幹:2.06 脳梁:- 松果体:- 末梢神経:- 脊柱:2.04 網膜:- 目:- 動脈:2.30 静脈:- リンパ節:2.81 末梢血:- 脾臓:2.26 胸腺:2.82 骨髄:- 脂肪:- 骨:1.97 皮膚:2.56
RNA-seq nodata
EST 子宮:- 胎盤:179.50 前立腺:30.90 卵巣:11.50 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:9.10        肺:40.20    膀胱:- 腎臓:8.10 下垂体:180.80 甲状腺:- 副腎:- 膵臓:56.30 乳腺:16.30 唾液腺:-
GeneChip nodata
CAGE 子宮:2.00 胎盤:2.31 前立腺:2.28 卵巣:2.57 精巣:1.48 心臓:- 骨格筋:- 食道:- 胃:2.26 腸:1.96 結腸:2.27     肝臓:2.51    肺:2.36 膀胱:2.05 腎臓:- 下垂体:2.22 甲状腺:- 副腎:2.59 膵臓:2.03 乳腺:2.97 唾液腺:-
RNA-seq nodata

IDs

Refseq ID XM_001479837
Gene ID 22034
Unigene ID Mm.292729
Probe set ID -
Ensembl ID -

オーソログ対応遺伝子

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染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8889548
8910514
9610637
10097072
10215628
10349636
10421844
10465784
10747026
10748240
11007897
11042159
11076861
11217851
11244088
11250893
11278268
11406619
11547829
11923871
11967542
11994463
12060722
12140561
12185073
12354380
12459498
12466851
12477932
12566447
12616498
12631284
12637570
12711536
12787561
12819136
12902324
12958312
14499111
14500659
14530355
14610273
14634083
14645259
14661019
14673102
14699584
15102471
15125833
15147900
15305292
15308666
15322147
15361868
15385464
15492225
15548667
15618518
15665823
15678102
15705807
15721744
15836773
15864310
15905851
16033648
16079148
16141072
16141073
16147974
16184196
16196101
16210631
16221674
16237096
16246731
16252010
16263713
16306937
16362041
16378096
16393988
16436380
16446357
16630834
16697380
16772369
16831874
16897814
16921377
17055451
17092936
17224624
17277780
17332487
17360955
17389358
17462996
17507094
17562858
17572386
17633018
17703191
17709375
17878362
17947236
17974599
17982070
18079694
18083102
18097000
18174161
18195092
18202703
18239685
18246070
18268035
18378686
18382763
18407828
18411265
18411338
18423196
18603409
18617513
18634786
18635759
18682563
18710948
18758450
18768464
18772140
18782768
18799149
18805969
18824541
18849341
18922473
18984593
18996842
19091594
19112497
19136968
19155515
19198591
19201866
19224920
19270748
19346732
19365810
19412180
19479062
19483718
19494812
19500387
19576795
19592497
19596990
19661270
19713527
19798431
19822644
19823099
19825828
19898473
19898489
20100871
20139273
20185725
20345905
20351308
20501938
20529958
20614026
20622119
20644648
21041452
21098220
21098228
21115689
21131124
21155952
21187332
21262968
21267068
21305609
21401811
21435586
21454471
21460221
21525932
21527253
21566132
21677750
21703539
21725320
21743479
21765415
21822257
21949653
22059479
22095711
22290431
22323536
22345171
22357600
22427868
22503986
22522491
22590573
22593578
22637723
22649194
22693634
22719861
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22749815
22842344
22851696
22860133
22863753
22904686
22925919
22935568
22984582
23028045
23042151
23148225
23355738
23376919
23381138
23536866
23707529
23776175
23782702
23791643
23799152
23825957
23867620
23907468
23909487
23911927
23914844
23918981
23942232
23951545
23960234
23962979
24058613
24114841
24163132
24170780
24492375
24558484
24578159
24777252

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007250  activation of NF-kappaB-inducing kinase activity
GO:0032147  activation of protein kinase activity
GO:0019886  antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0046849  bone remodeling
GO:0045453  bone resorption
GO:0048468  cell development
GO:0019221  cytokine-mediated signaling pathway
GO:0007249  I-kappaB kinase/NF-kappaB cascade
GO:0006955  immune response
GO:0070498  interleukin-1-mediated signaling pathway
GO:0007254  JNK cascade
GO:0043011  myeloid dendritic cell differentiation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001843  neural tube closure
GO:0042475  odontogenesis of dentine-containing tooth
GO:0009887  organ morphogenesis
GO:0001503  ossification
GO:0030316  osteoclast differentiation
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045084  positive regulation of interleukin-12 biosynthetic process
GO:0032743  positive regulation of interleukin-2 production
GO:0045410  positive regulation of interleukin-6 biosynthetic process
GO:0043507  positive regulation of JUN kinase activity
GO:0031666  positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0045672  positive regulation of osteoclast differentiation
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0002726  positive regulation of T cell cytokine production
GO:0042102  positive regulation of T cell proliferation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0051865  protein autoubiquitination
GO:0006461  protein complex assembly
GO:0070534  protein K63-linked ubiquitination
GO:0000209  protein polyubiquitination
GO:0016567  protein ubiquitination
GO:0042981  regulation of apoptosis
GO:0051023  regulation of immunoglobulin secretion
GO:0070555  response to interleukin-1
GO:0007165  signal transduction
GO:0050852  T cell receptor signaling pathway
GO:0042088  T-helper 1 type immune response

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0009898  internal side of plasma membrane
GO:0005811  lipid particle
GO:0031965  nuclear membrane
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0043234  protein complex

Molecular Function

GO:0042826  histone deacetylase binding
GO:0016874  ligase activity
GO:0046872  metal ion binding
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0005515  protein binding
GO:0043422  protein kinase B binding
GO:0019901  protein kinase binding
GO:0047485  protein N-terminus binding
GO:0004871  signal transducer activity
GO:0031996  thioesterase binding
GO:0031625  ubiquitin protein ligase binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding