nuclear receptor subfamily 1, group H, member 3

詳細情報を見る

同義遺伝子名

Nuclear orphan receptor LXR-alpha, LXR, RLD1, AU018371, Liver X receptor alpha, Unr1, LXR alpha, Lxra, nuclear receptor subfamily 1, group H, member 3, Oxysterols receptor LXR-alpha, Nr1h3

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:19.10 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:26.30 胸腺:- 骨髄:64.10 脂肪:- 骨:- 皮膚:7.90
GeneChip 大脳:5.40 小脳:6.21 脳幹:- 脳梁:- 松果体:- 末梢神経:5.84 脊柱:5.62 網膜:5.33 目:5.60 動脈:- 静脈:5.34 リンパ節:8.25 末梢血:- 脾臓:7.94 胸腺:- 骨髄:6.37 脂肪:8.06 骨:5.98 皮膚:5.96
CAGE 大脳:0.54 小脳:- 脳幹:0.69 脳梁:- 松果体:- 末梢神経:- 脊柱:1.11 網膜:- 目:- 動脈:3.36 静脈:- リンパ節:3.74 末梢血:- 脾臓:3.31 胸腺:1.90 骨髄:- 脂肪:- 骨:2.09 皮膚:1.42
RNA-seq 大脳:2.12 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:87.20 胎盤:- 前立腺:30.90 卵巣:114.90 精巣:88.70 心臓:18.60 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:10    膀胱:- 腎臓:- 下垂体:12.90 甲状腺:- 副腎:- 膵臓:28.10 乳腺:9.80 唾液腺:162
GeneChip 子宮:6.33 胎盤:5.94 前立腺:5.98 卵巣:6.34 精巣:6.70 心臓:6.59 骨格筋:7.11 食道:- 胃:5.99 腸:7.05 結腸:- 肝臓:9.33 肺:8.37 膀胱:6.27 腎臓:8.13 下垂体:6.12 甲状腺:- 副腎:6.55 膵臓:6.63 乳腺:7.21 唾液腺:5.78
CAGE 子宮:1.41 胎盤:1.54 前立腺:1.02 卵巣:1.60 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0.67 腸:3.06 結腸:2.79     肝臓:4.35    肺:2.78 膀胱:1.54 腎臓:- 下垂体:0.99 甲状腺:- 副腎:2.13 膵臓:1.30 乳腺:1.98 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:3.18 食道:- 胃:- 腸:- 結腸:-     肝臓:15.41        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_013839
Gene ID 22259
Unigene ID Mm.226900
Probe set ID 1450444_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000002108

オーソログ対応遺伝子

ヒト[3]  NM_001130101, NM_001130102, NM_005693
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

9630215
10049761
10349636
10675617
10725249
10890879
10922068
10968783
11042159
11076861
11090130
11149950
11208732
11217851
11238557
11546778
11682476
11714849
11781314
11792716
11851872
11901146
12040022
12054659
12086931
12097330
12105210
12138207
12145154
12177004
12193599
12193651
12196343
12368482
12435796
12446833
12466851
12477932
12518032
12524534
12531895
12542530
12551904
12554745
12588951
12601003
12612088
12730332
12815040
12897148
12947111
12970362
14521951
14610273
14679166
14681479
14699103
14699507
14703507
14739254
15052659
15060163
15146238
15171719
15292368
15319426
15371561
15479645
15525595
15561926
15591022
15601766
15618518
15674823
15680331
15761042
15831500
15930522
15941783
16007255
16054068
16106051
16106052
16123164
16141072
16141073
16141411
16249184
16260782
16325781
16424942
16447060
16498401
16505352
16511593
16547220
16614371
16806672
16823488
16825483
16869726
16876124
16895745
16943421
16949052
16956579
16971476
16973760
16981222
17088263
17107947
17166844
17177110
17218271
17256725
17296605
17341595
17369526
17445767
17563384
17628006
17657314
17684114
17726195
17873880
17908797
17936707
18055760
18079124
18195045
18202130
18276933
18287559
18292813
18318438
18330481
18356535
18372346
18450749
18450964
18547429
18566121
18611859
18614014
18769020
18772483
18787185
18806227
18840761
18949453
18983830
19032342
19036902
19052228
19067122
19119143
19122149
19136075
19196952
19201410
19238156
19325005
19342446
19366697
19380774
19395734
19436111
19487338
19520913
19608643
19646905
19690071
19717840
19721697
19787047
19796621
19889862
19966778
19996385
20005944
20037141
20037595
20049870
20059953
20080977
20110577
20118482
20125084
20159957
20193185
20211142
20375256
20388921
20412781
20494359
20615868
20674863
20679224
20854262
20932939
21034810
21103366
21123945
21134374
21187453
21266776
21267068
21343340
21349840
21398609
21441141
21492741
21504366
21521718
21558881
21562267
21593381
21609322
21630010
21677638
21677750
21715627
21757649
21784849
21889884
21898498
21933863
22073227
22152248
22156197
22158963
22323586
22415588
22415873
22454476
22481067
22484817
22547570
22580900
22610535
22673513
22694168
22723445
22739758
22829162
22891211
22969086
22984430
23021221
23029557
23063693
23073827
23077096
23085633
23099324
23110859
23159616
23266787
23292650
23318573
23333450
23348573
23359226
23419360
23554947
23675307
23686490
23747249
23762402
23770640
23788762
23823481
23836449
23867501
23897983
23990362
24201575
24206663
24259533
24277692
24438183
24603323
24699378
24747959

遺伝子オントロジー  (GO ID)

Biological Process

GO:0043277  apoptotic cell clearance
GO:0044255  cellular lipid metabolic process
GO:0071222  cellular response to lipopolysaccharide
GO:0042632  cholesterol homeostasis
GO:0006633  fatty acid biosynthetic process
GO:0030522  intracellular receptor-mediated signaling pathway
GO:0055088  lipid homeostasis
GO:0010887  negative regulation of cholesterol storage
GO:0050728  negative regulation of inflammatory response
GO:0032369  negative regulation of lipid transport
GO:0043031  negative regulation of macrophage activation
GO:0090188  negative regulation of pancreatic juice secretion
GO:0048550  negative regulation of pinocytosis
GO:0045861  negative regulation of proteolysis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0032270  positive regulation of cellular protein metabolic process
GO:0010875  positive regulation of cholesterol efflux
GO:0032376  positive regulation of cholesterol transport
GO:0045723  positive regulation of fatty acid biosynthetic process
GO:0051006  positive regulation of lipoprotein lipase activity
GO:0010870  positive regulation of receptor biosynthetic process
GO:0034145  positive regulation of toll-like receptor 4 signaling pathway
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0010867  positive regulation of triglyceride biosynthetic process
GO:0006355  regulation of transcription, DNA-dependent
GO:0032570  response to progesterone stimulus
GO:0043401  steroid hormone mediated signaling pathway
GO:0055092  sterol homeostasis
GO:0006351  transcription, DNA-dependent
GO:0070328  triglyceride homeostasis

Cellular Component

GO:0005737  cytoplasm
GO:0000790  nuclear chromatin
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0044212  DNA regulatory region binding
GO:0004879  ligand-dependent nuclear receptor activity
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0046965  retinoid X receptor binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0032810  sterol response element binding
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding