vascular endothelial growth factor A

 詳細情報を見る

同義遺伝子名

Vegf, VEGF120, VPF, Vascular endothelial growth factor A precursor, vascular endothelial growth factor A, Vegfa, Vascular permeability factor, VEGF-A

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST nodata
GeneChip 大脳:7.57 小脳:7.75 脳幹:- 脳梁:- 松果体:- 末梢神経:7.41 脊柱:7.81 網膜:8.74 目:7.07 動脈:- 静脈:7.04 リンパ節:7.26 末梢血:- 脾臓:7.56 胸腺:- 骨髄:6.34 脂肪:9.13 骨:7.02 皮膚:6.72
CAGE 大脳:3.84 小脳:- 脳幹:4.04 脳梁:- 松果体:- 末梢神経:- 脊柱:4.12 網膜:- 目:- 動脈:5.67 静脈:- リンパ節:3.97 末梢血:- 脾臓:3.51 胸腺:2.52 骨髄:- 脂肪:- 骨:3.83 皮膚:4.12
RNA-seq 大脳:5.96 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST nodata
GeneChip 子宮:8.23 胎盤:8.62 前立腺:7.42 卵巣:8.11 精巣:5.62 心臓:10.44 骨格筋:9.25 食道:- 胃:8.13 腸:7.80 結腸:- 肝臓:8.53 肺:10.73 膀胱:7.60 腎臓:9.34 下垂体:7.19 甲状腺:- 副腎:10.76 膵臓:8.08 乳腺:8.65 唾液腺:8.47
CAGE 子宮:4.48 胎盤:4.89 前立腺:3.61 卵巣:4.18 精巣:1.34 心臓:- 骨格筋:- 食道:- 胃:4.42 腸:4.97 結腸:4.37     肝臓:5.46    肺:6.43 膀胱:3.81 腎臓:- 下垂体:3.44 甲状腺:- 副腎:5.77 膵臓:4.97 乳腺:4.66 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:4.77 食道:- 胃:- 腸:- 結腸:-     肝臓:6.70        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_001025250
Gene ID 22339
Unigene ID -
Probe set ID 1420909_at  [Mouse430_2]
Ensembl ID ENSMUSG00000023951

オーソログ対応遺伝子

ヒト[14]  NM_001025366, NM_001025367, NM_001025368, NM_001025369, NM_001025370, NM_001033756, NM_001171622, NM_001171623, NM_001171624, NM_001171625, NM_001171626, NM_001171627, NM_001171628, NM_001171629, NM_001171630, NM_001204384, NM_001204385, NM_003376
ラット[19]  NM_001110333, NM_001110334, NM_001110335, NM_001110336, NM_031836, NM_001033756, NM_001171622, NM_001171623, NM_001171624, NM_001171625, NM_001171626, NM_001171627, NM_001171628, NM_001171629, NM_001171630, NM_001204384, NM_001204385, NM_003376

染色体

17C  [46,153,942  -  46,169,326]

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1592003
1644816
7490564
7534783
7647376
7681362
7683699
7803491
7846076
7933988
8090202
8119973
8573716
8602241
8602242
8602835
8607868
8614412
8632007
8637916
8702615
8756616
8815891
8963443
8968091
9012504
9113979
9153276
9166595
9212753
9256442
9401819
9446618
9665379
9665459
9689915
9778514
9792673
9806910
9846489
9861052
10021335
10022836
10027394
10027415
10208743
10229225
10323857
10328919
10335479
10349636
10364225
10395786
10428027
10433823
10495271
10575000
10581076
10587525
10617467
10653008
10654595
10675351
10685072
10700190
10704390
10705382
10706142
10716993
10803598
10813585
10878616
10926756
10942527
10943840
10952892
11032855
11042159
11066091
11076861
11084652
11090062
11124112
11165481
11169844
11169851
11171333
11181640
11217851
11226286
11230154
11267659
11289156
11290292
11290536
11304494
11331305
11331753
11352659
11381139
11381259
11437453
11439183
11458389
11472838
11509733
11549290
11563986
11577200
11599061
11691837
11728162
11731620
11775025
11777931
11804779
11809716
11812828
11815711
11827992
11839592
11897712
11897714
11907124
11919510
11927538
11934854
11934855
11937493
11943666
11953313
11959648
12032352
12039984
12048246
12053176
12057925
12060561
12070272
12086877
12087404
12093914
12112468
12149478
12151311
12192060
12213803
12226475
12368264
12370313
12372425
12381667
12386279
12393646
12397601
12415262
12444056
12446788
12461084
12466305
12466851
12477932
12482580
12482858
12537522
12538631
12539040
12552636
12556420
12588999
12591918
12618525
12628185
12714610
12716475
12736220
12746324
12761846
12810642
12810677
12814555
12829717
12834865
12847526
12852851
12858545
12885771
12890722
12904583
12912908
12917333
12975317
13678594
14506249
14507649
14512017
14517396
14530359
14550787
14633603
14651929
14662796
14699103
14722611
14728692
14729577
14729621
14745002
14969389
14980515
14983237
14998491
14998923
15001532
15003169
15016731
15020256
15063179
15067085
15072995
15073147
15073150
15081307
15084712
15100155
15132990
15136139
15143069
15150105
15161688
15175265
15175342
15184386
15185205
15193536
15196703
15202016
15208295
15217829
15259010
15262905
15305294
15306695
15326102
15339668
15371263
15383400
15459110
15465485
15467755
15477421
15488701
15489334
15501235
15501241
15504909
15504975
15509779
15515055
15531367
15545635
15550485
15563592
15572520
15579459
15582599
15601855
15601856
15613470
15614762
15629128
15652753
15670761
15673567
15689378
15705785
15710418
15716406
15765121
15768385
15800063
15809353
15817666
15882861
15896317
15911882
15919073
15920019
15922088
15927453
15944181
15947259
15956982
15958580
15964546
16000382
16002046
16027358
16039615
16039638
16044082
16105646
16105884
16107612
16107693
16141072
16141073
16164632
16164642
16171822
16172161
16172168
16189264
16189273
16219308
16223785
16224065
16234975
16245301
16251428
16259067
16269210
16291795
16293653
16302230
16324270
16344007
16355211
16375885
16396910
16428272
16432225
16436493
16462734
16470614
16510872
16514057
16556738
16595708
16597608
16602821
16650815
16678147
16699073
16702604
16718361
16732297
16735996
16752188
16778080
16782887
16799060
16799557
16806288
16824955
16825198
16831171
16835303
16877353
16880268
16887817
16887829
16891392
16895970
16935278
16966370
16973968
16980969
16990600
17003502
17013884
17014841
17050862
17053052
17065333
17065555
17088559
17095533
17121831
17170753
17180351
17187775
17211450
17215071
17215402
17237427
17240354
17243865
17249570
17249573
17249574
17255526
17264168
17277743
17289903
17293480
17296941
17306552
17324777
17332426
17334372
17336904
17360578
17360669
17374694
17381847
17405882
17417650
17418408
17428830
17460146
17464208
17470636
17475663
17478585
17498737
17509611
17522124
17537803
17543594
17544391
17548469
17548584
17553957
17560563
17573777
17575261
17576813
17583691
17585015
17589348
17597103
17624309
17625067
17625068
17626017
17646268
17654674
17660984
17670744
17673674
17687003
17693120
17714861
17719546
17784876
17846500
17881491
17913788
17948123
17957349
17962514
17965409
17981115
17982705
17989695
18006519
18006829
18025304
18046016
18052755
18057050
18079413
18079435
18083119
18093989
18094043
18094712
18097059
18097062
18159117
18180305
18199548
18202762
18205601
18206867
18216538
18233956
18234958
18251599
18264090
18268040
18272846
18285708
18287559
18288196
18297725
18300052
18300426
18304943
18328795
18330587
18334839
18358466
18379992
18381816
18388887
18390541
18392108
18403633
18414495
18424890
18430730
18443354
18452614
18478024
18483622
18492486
18494554
18497067
18501628
18508041
18509509
18516298
18521186
18534615
18550647
18559975
18568073
18583712
18599509
18599600
18600399
18606782
18617751
18621544
18632559
18632621
18640270
18641052
18653562
18655767
18668138
18681864
18683887
18688025
18698254
18702304
18710940
18714400
18723443
18724005
18725519
18728224
18753609
18757513
18758859
18763309
18768843
18776949
18777454
18782574
18789802
18802023
18804439
18818406
18822285
18824721
18832393
18835464
18844982
18845627
18849336
18926584
18927085
18940803
18952601
18974875
18978936
18978955
18981216
18996357
18997773
19013462
19015235
19023080
19033661
19035465
19037231
19056388
19060119
19075228
19087268
19087347
19088378
19112107
19114984
19115638
19118187
19120890
19138992
19144989
19147955
19150651
19154719
19174516
19176122
19181962
19228596
19228841
19233483
19237429
19249018
19249680
19255254
19261698
19304944
19307054
19320717
19336220
19339510
19346498
19349367
19358726
19375650
19401459
19407242
19407245
19411759
19416849
19419310
19433784
19435561
19464254
19464280
19477952
19498186
19501129
19521566
19535097
19553159
19557172
19561313
19607824
19617630
19619540
19631637
19634141
19638429
19644017
19646811
19652084
19653325
19661463
19666558
19666581
19703439
19706683
19710169
19710174
19737384
19737917
19754224
19764560
19765632
19768732
19781348
19786548
19788349
19790065
19805173
19805353
19805546
19809162
19834063
19837659
19841260
19841617
19847951
19853064
19853564
19853842
19881219
19885588
19893619
19906640
19918242
19918884
20006606
20010698
20023214
20025971
20026662
20035012
20040492
20042679
20067573
20072992
20079728
20080568
20089971
20103650
20123094
20133819
20141840
20142327
20142499
20145550
20167862
20173040
20179096
20179357
20185832
20204282
20219142
20221394
20230750
20303008
20332116
20339091
20339541
20346106
20346184
20354184
20382171
20382450
20382704
20388654
20392836
20399150
20404134
20413734
20415720
20421635
20432243
20441791
20446021
20450250
20462640
20463289
20495570
20498081
20501654
20501856
20528744
20530741
20544853
20548231
20554972
20568246
20596014
20598569
20606119
20619341
20622121
20659482
20664058
20682292
20684271
20684947
20686173
20686684
20688931
20688932
20692235
20702774
20705246
20708602
20711984
20713592
20715981
20737509
20807526
20811045
20816797
20817051
20827751
20829436
20850416
20864798
20884890
20926767
20974861
20975697
20978081
21034500
21068311
21086498
21145972
21149574
21160191
21164138
21173261
21179479
21187644
21198982
21217667
21225223
21236558
21252157
21267068
21269609
21270129
21278304
21282654
21293003
21293011
21324396
21325621
21352545
21355888
21356362
21382954
21385942
21386905
21402740
21421844
21435445
21435467
21436157
21436353
21474827
21475978
21494559
21498671
21501344
21515678
21519870
21527748
21536099
21556948
21558971
21593423
21595947
21597001
21605070
21606590
21622854
21646395
21646723
21654748
21658587
21658588
21670467
21693521
21696760
21704027
21704616
21724832
21728823
21731759
21744331
21745297
21747167
21757289
21772310
21778339
21784979
21793044
21803034
21804034
21804139
21809376
21828096
21867538
21872252
21911092
21911392
21922279
21937443
21940662
21960121
21985298
22009883
22012397
22020326
22030397
22035642
22037736
22045186
22048155
22058334
22067127
22078489
22084310
22096573
22109109
22110141
22123256
22137122
22150821
22158707
22162090
22167188
22171010
22171708
22183346
22195822
22206010
22206865
22212769
22232745
22262122
22275534
22282193
22287577
22302810
22306286
22318228
22318724
22324377
22326698
22327215
22330806
22350794
22354840
22362129
22363445
22374305
22379030
22379108
22392094
22408005
22421594
22426001
22451920
22457593
22470452
22473072
22499584
22504313
22516064
22522611
22539593
22546005
22546694
22556263
22569048
22570350
22571958
22577176
22581517
22583764
22589746
22593269
22610792
22611036
22614766
22622799
22627278
22627288
22640974
22644934
22653056
22670674
22682244
22692279
22718316
22733742
22750006
22768384
22808199
22810360
22815682
22815987
22821840
22826212
22842346
22843502
22848663
22885149
22886301
22911456
22919064
22925884
22951644
22954336
22957090
22961079
22961440
22965144
22966168
22996192
23002035
23007467
23023706
23063659
23071670
23074224
23093658
23093773
23099493
23103584
23171542
23178125
23185546
23185615
23233163
23233787
23249422
23257244
23274064
23279742
23283573
23307787
23307965
23312284
23317887
23319657
23319736
23334418
23349620
23376683
23378532
23386058
23390317
23391391
23395391
23395890
23416159
23466739
23468957
23514785
23523683
23537525
23548588
23554936
23560444
23562080
23565059
23567158
23568776
23585229
23602833
23608225
23610556
23627689
23629862
23649506
23664004
23682021
23682123
23698113
23707896
23712501
23715613
23722408
23726969
23728380
23729446
23744993
23750244
23756254
23758212
23786956
23795287
23818623
23840778
23843451
23845873
23853117
23863481
23884445
23884891
23896411
23908593
23916658
23918367
23959876
23962989
23990021
24016759
24027281
24043765
24043815
24113869
24139045
24166715
24169552
24218567
24240089
24262984
24353059
24366884
24401374
24403062
24503129
24505137
24523345
24558195
24574008
24624789
24650547
24659690
24736431
24746698

遺伝子オントロジー  (GO ID)

Biological Process

GO:0032147  activation of protein kinase activity
GO:0001525  angiogenesis
GO:0048844  artery morphogenesis
GO:0002575  basophil chemotaxis
GO:0001568  blood vessel development
GO:0048514  blood vessel morphogenesis
GO:0001974  blood vessel remodeling
GO:0048754  branching morphogenesis of a tube
GO:0048593  camera-type eye morphogenesis
GO:0048739  cardiac muscle fiber development
GO:0060948  cardiac vascular smooth muscle cell development
GO:0060326  cell chemotaxis
GO:0030154  cell differentiation
GO:0048469  cell maturation
GO:0016477  cell migration
GO:0002042  cell migration involved in sprouting angiogenesis
GO:0008283  cell proliferation
GO:0071456  cellular response to hypoxia
GO:0060982  coronary artery morphogenesis
GO:0003169  coronary vein morphogenesis
GO:0030855  epithelial cell differentiation
GO:0042462  eye photoreceptor cell development
GO:0040007  growth
GO:0003007  heart morphogenesis
GO:0001701  in utero embryonic development
GO:0050930  induction of positive chemotaxis
GO:0001822  kidney development
GO:0007595  lactation
GO:0048286  lung alveolus development
GO:0030324  lung development
GO:0030225  macrophage differentiation
GO:0060749  mammary gland alveolus development
GO:0007498  mesoderm development
GO:0030224  monocyte differentiation
GO:0048255  mRNA stabilization
GO:0007275  multicellular organismal development
GO:0043066  negative regulation of apoptosis
GO:0045779  negative regulation of bone resorption
GO:0043154  negative regulation of caspase activity
GO:0043524  negative regulation of neuron apoptosis
GO:0043069  negative regulation of programmed cell death
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0007399  nervous system development
GO:0048666  neuron development
GO:0003151  outflow tract morphogenesis
GO:0001541  ovarian follicle development
GO:0001569  patterning of blood vessels
GO:0050918  positive chemotaxis
GO:0045766  positive regulation of angiogenesis
GO:0043536  positive regulation of blood vessel endothelial cell migration
GO:0090190  positive regulation of branching involved in ureteric bud morphogenesis
GO:0045785  positive regulation of cell adhesion
GO:0051781  positive regulation of cell division
GO:0030335  positive regulation of cell migration
GO:0090050  positive regulation of cell migration involved in sprouting angiogenesis
GO:0008284  positive regulation of cell proliferation
GO:0051272  positive regulation of cellular component movement
GO:0032793  positive regulation of CREB transcription factor activity
GO:0010595  positive regulation of endothelial cell migration
GO:0001938  positive regulation of endothelial cell proliferation
GO:0050679  positive regulation of epithelial cell proliferation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0051894  positive regulation of focal adhesion formation
GO:0010628  positive regulation of gene expression
GO:0043406  positive regulation of MAP kinase activity
GO:0060754  positive regulation of mast cell chemotaxis
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0002052  positive regulation of neuroblast proliferation
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0050927  positive regulation of positive chemotaxis
GO:0031954  positive regulation of protein amino acid autophosphorylation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0031334  positive regulation of protein complex assembly
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0090037  positive regulation of protein kinase C signaling cascade
GO:0010740  positive regulation of protein kinase cascade
GO:0002092  positive regulation of receptor internalization
GO:0009967  positive regulation of signal transduction
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0030949  positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0043117  positive regulation of vascular permeability
GO:0031077  post-embryonic camera-type eye development
GO:0060319  primitive erythrocyte differentiation
GO:0008360  regulation of cell shape
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0001666  response to hypoxia
GO:0043129  surfactant homeostasis
GO:0042088  T-helper 1 type immune response
GO:0035148  tube lumen formation
GO:0048010  vascular endothelial growth factor receptor signaling pathway
GO:0001944  vasculature development

Cellular Component

GO:0005604  basement membrane
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0016020  membrane
GO:0031988  membrane-bounded vesicle
GO:0005886  plasma membrane
GO:0030141  secretory granule

Molecular Function

GO:0042056  chemoattractant activity
GO:0005125  cytokine activity
GO:0001968  fibronectin binding
GO:0008083  growth factor activity
GO:0008201  heparin binding
GO:0042802  identical protein binding
GO:0005161  platelet-derived growth factor receptor binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0048018  receptor agonist activity
GO:0043183  vascular endothelial growth factor receptor 1 binding
GO:0043184  vascular endothelial growth factor receptor 2 binding
GO:0005172  vascular endothelial growth factor receptor binding