gremlin 1

同義遺伝子名

Grem1, Down-regulated in Mos-transformed cells protein, Cysteine knot superfamily 1, BMP antagonist 1, Drm, Gremlin-1 precursor, gremlin 1, gremlin, ld, Cktsf1b1

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:-

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:79

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

GeneChip

大脳:5.36

小脳:5.12

脳幹:-

脳梁:-

松果体:-

末梢神経:5.09

脊柱:5.33

網膜:5.12

目:5.83

動脈:-

静脈:5.39

リンパ節:7.71

末梢血:-

脾臓:5.67

胸腺:-

骨髄:6.07

脂肪:5.03

骨:6.13

皮膚:9.40

CAGE

大脳:0

小脳:-

脳幹:0.23

脳梁:-

松果体:-

末梢神経:-

脊柱:0.66

網膜:-

目:-

動脈:0.77

静脈:-

リンパ節:3.29

末梢血:-

脾臓:1.17

胸腺:0.27

骨髄:-

脂肪:-

骨:2.53

皮膚:3.46

RNA-seq

大脳:0.28

小脳:0.28

脳幹:0.28

脳梁:0.28

松果体:0.28

末梢神経:0.28

脊柱:0.28

網膜:0.28

目:0.28

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:17.60

肝臓:-

肺:10

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

GeneChip

子宮:4.72

胎盤:5.13

前立腺:4.84

卵巣:5.19

精巣:5.06

心臓:5.24

骨格筋:5.21

食道:-

胃:5.87

腸:7.79

結腸:-

肝臓:5.14

肺:5.05

膀胱:4.95

腎臓:4.99

下垂体:7.03

甲状腺:-

副腎:4.76

膵臓:5.13

乳腺:5.32

唾液腺:5.69

CAGE

子宮:0

胎盤:0.25

前立腺:0

卵巣:2.19

精巣:0

心臓:-

骨格筋:-

食道:-

胃:2.95

腸:3.43

結腸:3.36

肝臓:0

肺:0.55

膀胱:1.50

腎臓:-

下垂体:3.13

甲状腺:-

副腎:1.38

膵臓:0.84

乳腺:0.34

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_011824
Gene ID	23892
Unigene ID	Mm.166318
Probe set ID	1425357_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000074934

オーソログ対応遺伝子

ヒト[2]	NM_001191322, NM_001191323, NM_013372
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR006207

Cystine knot, C-terminal

遺伝子オントロジー (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0002042	cell migration involved in sprouting angiogenesis
GO:0000902	cell morphogenesis
GO:0007267	cell-cell signaling
GO:0030199	collagen fibril organization
GO:0048263	determination of dorsal identity
GO:0030326	embryonic limb morphogenesis
GO:0043542	endothelial cell migration
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0030514	negative regulation of BMP signaling pathway
GO:0030502	negative regulation of bone mineralization
GO:0046851	negative regulation of bone remodeling
GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis
GO:0030308	negative regulation of cell growth
GO:0002689	negative regulation of leukocyte chemotaxis
GO:0090027	negative regulation of monocyte chemotaxis
GO:0033689	negative regulation of osteoblast proliferation
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0090090	negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0009887	organ morphogenesis
GO:0045766	positive regulation of angiogenesis
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
GO:0008284	positive regulation of cell proliferation
GO:0042346	positive regulation of NF-kappaB import into nucleus
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0002092	positive regulation of receptor internalization
GO:0051973	positive regulation of telomerase activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0009954	proximal/distal pattern formation
GO:0010717	regulation of epithelial to mesenchymal transition
GO:0051893	regulation of focal adhesion formation
GO:0032872	regulation of stress-activated MAPK cascade
GO:0060676	ureteric bud formation

Cellular Component

GO:0009986	cell surface
GO:0005576	extracellular region
GO:0005615	extracellular space

Molecular Function

GO:0005125	cytokine activity
GO:0043395	heparan sulfate proteoglycan binding
GO:0030296	protein tyrosine kinase activator activity
GO:0048018	receptor agonist activity
GO:0043184	vascular endothelial growth factor receptor 2 binding

gremlin 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function