nucleotide-binding oligomerization domain containing 2

同義遺伝子名

Caspase recruitment domain-containing protein 15, caspase recruitment domain family, member 15, ACUG, F830032C23Rik, CD, Card15, Protein Nod2, BLAU, IBD1, Nod2

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:1.70

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:19.10

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:291.60

末梢血:-

脾臓:289.70

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

GeneChip

nodata

CAGE

nodata

RNA-seq

大脳:0.93

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:13.80

前立腺:-

卵巣:23

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:17.60

肝臓:-

肺:-

膀胱:-

腎臓:8.10

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:3.30

唾液腺:-

GeneChip

nodata

CAGE

nodata

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:0.95

食道:-

胃:-

腸:-

結腸:-

肝臓:0

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_145857
Gene ID	257632
Unigene ID	Mm.222633
Probe set ID	-
Ensembl ID	ENSMUSG00000055994

オーソログ対応遺伝子

ヒト[1]	NM_022162
ラット [0]

染色体

8C3 [91,171,214 - 91,212,373]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR001315	Caspase Recruitment
IPR011029	DEATH-like

遺伝子オントロジー (GO ID)

Biological Process

GO:0002253	activation of immune response
GO:0071224	cellular response to peptidoglycan
GO:0002367	cytokine production during immune response
GO:0006952	defense response
GO:0042742	defense response to bacterium
GO:0050830	defense response to Gram-positive bacterium
GO:0016045	detection of bacterium
GO:0009595	detection of biotic stimulus
GO:0032498	detection of muramyl dipeptide
GO:0002381	immunoglobulin production during immune response
GO:0006954	inflammatory response
GO:0002227	innate immune response in mucosa
GO:0002282	microglial cell activation during immune response
GO:0044130	negative regulation of growth of symbiont in host
GO:0002862	negative regulation of inflammatory response to antigenic stimulus
GO:0032689	negative regulation of interferon-gamma production
GO:0032695	negative regulation of interleukin-12 production
GO:0032701	negative regulation of interleukin-18 production
GO:0032703	negative regulation of interleukin-2 production
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0002710	negative regulation of T cell mediated immunity
GO:0034136	negative regulation of toll-like receptor 2 signaling pathway
GO:0032720	negative regulation of tumor necrosis factor production
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity
GO:0050871	positive regulation of B cell activation
GO:0006965	positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria
GO:0008284	positive regulation of cell proliferation
GO:0002606	positive regulation of dendritic cell antigen processing and presentation
GO:0002732	positive regulation of dendritic cell cytokine production
GO:0050679	positive regulation of epithelial cell proliferation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045089	positive regulation of innate immune response
GO:0032731	positive regulation of interleukin-1 beta production
GO:0050718	positive regulation of interleukin-1 beta secretion
GO:0032733	positive regulation of interleukin-10 production
GO:0032735	positive regulation of interleukin-12 production
GO:0032740	positive regulation of interleukin-17 production
GO:0032755	positive regulation of interleukin-6 production
GO:0046330	positive regulation of JNK cascade
GO:0043410	positive regulation of MAPKKK cascade
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process
GO:0045747	positive regulation of Notch signaling pathway
GO:0051353	positive regulation of oxidoreductase activity
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0050766	positive regulation of phagocytosis
GO:0043552	positive regulation of phosphoinositide 3-kinase activity
GO:0060585	positive regulation of prostaglandin-endoperoxidase synthase activity
GO:0031398	positive regulation of protein ubiquitination
GO:0032874	positive regulation of stress-activated MAPK cascade
GO:0002830	positive regulation of T-helper 2 type immune response
GO:0032760	positive regulation of tumor necrosis factor production
GO:0051259	protein oligomerization
GO:0042981	regulation of apoptosis
GO:0090022	regulation of neutrophil chemotaxis
GO:0043330	response to exogenous dsRNA
GO:0032496	response to lipopolysaccharide
GO:0032495	response to muramyl dipeptide
GO:0032494	response to peptidoglycan
GO:0007165	signal transduction

Cellular Component

GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005622	intracellular
GO:0005886	plasma membrane
GO:0008180	signalosome
GO:0031982	vesicle

Molecular Function

GO:0005524	ATP binding
GO:0050700	CARD domain binding
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters
GO:0019899	enzyme binding
GO:0032500	muramyl dipeptide binding
GO:0000166	nucleotide binding
GO:0042834	peptidoglycan binding
GO:0005515	protein binding
GO:0019901	protein kinase binding

nucleotide-binding oligomerization domain containing 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function