mitogen-activated protein kinase 3

同義遺伝子名

Mitogen-activated protein kinase 3, MAPK 1, Extracellular signal-regulated kinase 1, Mapk3, p44erk1, Erk1, mitogen activated protein kinase 3, MAP kinase 1, Prkm3, p44mapk, ERT2, MNK1, p44 MAP kinase, Microtubule-associated protein 2 kinase, Erk-1, p44-ERK1, ERK-1, Esrk1, Insulin-stimulated MAP2 kinase, p44-MAPK

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:43.40

小脳:-

脳幹:-

脳梁:-

松果体:515.60

末梢神経:38.20

脊柱:-

網膜:64.30

目:53.20

動脈:-

静脈:-

リンパ節:21.60

末梢血:57.50

脾臓:13.20

胸腺:69.20

骨髄:-

脂肪:212.70

骨:87.70

皮膚:71.30

GeneChip

大脳:9.64

小脳:8.86

脳幹:-

脳梁:-

松果体:-

末梢神経:12.17

脊柱:10.07

網膜:8.35

目:8.98

動脈:-

静脈:9.16

リンパ節:8.72

末梢血:-

脾臓:8.62

胸腺:-

骨髄:9.43

脂肪:8.95

骨:9.26

皮膚:9.44

CAGE

大脳:3.28

小脳:-

脳幹:3.40

脳梁:-

松果体:-

末梢神経:-

脊柱:3.55

網膜:-

目:-

動脈:2.93

静脈:-

リンパ節:2.64

末梢血:-

脾臓:2.52

胸腺:1.75

骨髄:-

脂肪:-

骨:3.57

皮膚:3.20

RNA-seq

大脳:42.70

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:174.50

胎盤:27.60

前立腺:-

卵巣:68.90

精巣:22.20

心臓:37.20

骨格筋:71

食道:-

胃:65.50

腸:-

結腸:475.80

肝臓:18.10

肺:210.90

膀胱:-

腎臓:80.60

下垂体:167.90

甲状腺:224.90

副腎:-

膵臓:28.10

乳腺:195.90

唾液腺:162

GeneChip

子宮:10.08

胎盤:8.76

前立腺:9.85

卵巣:9.93

精巣:9.83

心臓:8.70

骨格筋:8.02

食道:-

胃:10.91

腸:11.03

結腸:-

肝臓:8.16

肺:10.65

膀胱:9.53

腎臓:8.68

下垂体:9.10

甲状腺:-

副腎:9.23

膵臓:8.63

乳腺:8.91

唾液腺:8.92

CAGE

子宮:3.51

胎盤:2.82

前立腺:4.44

卵巣:3.59

精巣:3.95

心臓:-

骨格筋:-

食道:-

胃:4.22

腸:3.95

結腸:4.51

肝臓:2.64

肺:4.05

膀胱:3.49

腎臓:-

下垂体:3.08

甲状腺:-

副腎:3.47

膵臓:3.10

乳腺:2.57

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:5.43

食道:-

胃:-

腸:-

結腸:-

肝臓:7.63

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_011952
Gene ID	26417
Unigene ID	Mm.8385
Probe set ID	1427060_at [Mouse430_2]
Ensembl ID	ENSMUSG00000063065

オーソログ対応遺伝子

ヒト[3]	NM_001040056, NM_001109891, NM_002746
ラット[3]	NM_001040056, NM_001109891, NM_002746

染色体

遺伝子ファミリー (Interpro ID)

IPR008349	ERK1/2 MAP kinase
IPR008350	ERK3/4 MAP kinase
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed (Pubmed ID)

1437147
1716439
1717989
6966611
7478566
7592886
7592946
7619503
7797459
7889942
7997269
8108135
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24161523
24184684
24259565
24269886
24275659
24431450
24486509
24495410
24501377
24523460
24550287
24657659

遺伝子オントロジー (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0030509	BMP signaling pathway
GO:0051216	cartilage development
GO:0007049	cell cycle
GO:0070498	interleukin-1-mediated signaling pathway
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0000165	MAPKKK cascade
GO:0008152	metabolic process
GO:0000189	nuclear translocation of MAPK
GO:0009887	organ morphogenesis
GO:0016310	phosphorylation
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0035066	positive regulation of histone acetylation
GO:0033129	positive regulation of histone phosphorylation
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045727	positive regulation of translation
GO:0006468	protein amino acid phosphorylation
GO:0006461	protein complex assembly
GO:0051493	regulation of cytoskeleton organization
GO:0090170	regulation of Golgi inheritance
GO:0032872	regulation of stress-activated MAPK cascade
GO:0051090	regulation of transcription factor activity
GO:0006974	response to DNA damage stimulus
GO:0070849	response to epidermal growth factor stimulus
GO:0043330	response to exogenous dsRNA
GO:0032496	response to lipopolysaccharide
GO:0009636	response to toxin
GO:0019233	sensory perception of pain
GO:0007165	signal transduction
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005901	caveola
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005829	cytosol
GO:0005769	early endosome
GO:0005925	focal adhesion
GO:0005794	Golgi apparatus
GO:0005622	intracellular
GO:0005770	late endosome
GO:0015630	microtubule cytoskeleton
GO:0005739	mitochondrion
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0043234	protein complex
GO:0031143	pseudopodium

Molecular Function

GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0004707	MAP kinase activity
GO:0000166	nucleotide binding
GO:0019902	phosphatase binding
GO:0001784	phosphotyrosine binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

mitogen-activated protein kinase 3

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function