solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1

詳細情報を見る

同義遺伝子名

Nherf, Slc9a3r1, Na(+)/H(+) exchange regulatory cofactor NHE-RF, EBP-50, Regulatory cofactor of Na(+)/H(+) exchanger, MGC95776, EBP50, NHERF-1, sodium-hydrogen exchanger regulatory factor, Sodium-hydrogen exchanger regulatory factor 1, NHE-RF, Ezrin-radixin-moesin-binding phosphoprotein 50

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:74.70 小脳:92.10 脳幹:- 脳梁:- 松果体:257.80 末梢神経:38.20 脊柱:236.40 網膜:- 目:30.40 動脈:168.80 静脈:- リンパ節:43.20 末梢血:14.40 脾臓:79 胸腺:197.60 骨髄:218 脂肪:- 骨:37.60 皮膚:110.80
GeneChip 大脳:8.63 小脳:8.92 脳幹:- 脳梁:- 松果体:- 末梢神経:8.75 脊柱:9.18 網膜:8.91 目:7.90 動脈:- 静脈:7.80 リンパ節:9.65 末梢血:- 脾臓:9.75 胸腺:- 骨髄:9.26 脂肪:7.92 骨:8.71 皮膚:7.69
CAGE 大脳:3.15 小脳:- 脳幹:3.26 脳梁:- 松果体:- 末梢神経:- 脊柱:3.22 網膜:- 目:- 動脈:2.53 静脈:- リンパ節:3.02 末梢血:- 脾臓:2.82 胸腺:3.89 骨髄:- 脂肪:- 骨:3.14 皮膚:3.16
RNA-seq 大脳:13.30 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:359 前立腺:- 卵巣:34.50 精巣:7.40 心臓:130.20 骨格筋:- 食道:- 胃:130.90 腸:258.80 結腸:176.20     肝臓:172        肺:110.50    膀胱:- 腎臓:104.80 下垂体:90.40 甲状腺:337.40 副腎:- 膵臓:37.50 乳腺:52.20 唾液腺:108
GeneChip 子宮:9.32 胎盤:9.78 前立腺:9.32 卵巣:9.23 精巣:8.55 心臓:7.44 骨格筋:7.31 食道:- 胃:11.18 腸:11.76 結腸:- 肝臓:11.10 肺:9.26 膀胱:8.68 腎臓:11.31 下垂体:7.68 甲状腺:- 副腎:7.15 膵臓:8.66 乳腺:9.03 唾液腺:8.71
CAGE 子宮:3.14 胎盤:3.87 前立腺:3.62 卵巣:3.36 精巣:3.87 心臓:- 骨格筋:- 食道:- 胃:4.40 腸:6.14 結腸:6.25     肝臓:5.32    肺:3.50 膀胱:3.40 腎臓:- 下垂体:2.53 甲状腺:- 副腎:2.46 膵臓:3.32 乳腺:4.06 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.36 食道:- 胃:- 腸:- 結腸:-     肝臓:25.21        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0007191  activation of adenylate cyclase activity by dopamine receptor signaling pathway
GO:0060158  activation of phospholipase C activity by dopamine receptor signaling pathway
GO:0032782  bile acid secretion
GO:0019933  cAMP-mediated signaling
GO:0030643  cellular phosphate ion homeostasis
GO:0034613  cellular protein localization
GO:0034635  glutathione transport
GO:0030033  microvillus assembly
GO:0030336  negative regulation of cell migration
GO:0008285  negative regulation of cell proliferation
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0014067  negative regulation of phosphoinositide 3-kinase cascade
GO:0010642  negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0051898  negative regulation of protein kinase B signaling cascade
GO:0010766  negative regulation of sodium ion transport
GO:0032416  negative regulation of sodium:hydrogen antiporter activity
GO:0044062  regulation of excretion
GO:0045859  regulation of protein kinase activity
GO:0070293  renal absorption
GO:0003096  renal sodium ion transport
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0045177  apical part of cell
GO:0016324  apical plasma membrane
GO:0031526  brush border membrane
GO:0042995  cell projection
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005902  microvillus
GO:0031528  microvillus membrane
GO:0005886  plasma membrane

Molecular Function

GO:0031698  beta-2 adrenergic receptor binding
GO:0008013  beta-catenin binding
GO:0017081  chloride channel regulator activity
GO:0050780  dopamine receptor binding
GO:0070851  growth factor receptor binding
GO:0030165  PDZ domain binding
GO:0019902  phosphatase binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0032947  protein complex scaffold
GO:0019904  protein domain specific binding
GO:0043621  protein self-association
GO:0005102  receptor binding