TAO kinase 2

 詳細情報を見る

同義遺伝子名

1110033K02Rik, PSK1, B230344N16, TAO1, Taok2, TAO kinase 2, Thousand and one amino acid protein 2, Serine/threonine-protein kinase TAO2, TAO2, MAP3K17, KIAA0881, Kiaa0881, mKIAA0881, PSK

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:48.60 小脳:- 脳幹:63.60 脳梁:- 松果体:- 末梢神経:95.50 脊柱:94.60 網膜:96.40 目:91.20 動脈:- 静脈:- リンパ節:32.40 末梢血:- 脾臓:52.70 胸腺:- 骨髄:115.40 脂肪:- 骨:37.60 皮膚:39.60
GeneChip nodata
CAGE 大脳:3.04 小脳:- 脳幹:2.90 脳梁:- 松果体:- 末梢神経:- 脊柱:2.90 網膜:- 目:- 動脈:1.85 静脈:- リンパ節:2.50 末梢血:- 脾臓:2.52 胸腺:2.82 骨髄:- 脂肪:- 骨:2.37 皮膚:2.49
RNA-seq 大脳:14.72 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:55.20 前立腺:30.90 卵巣:103.40 精巣:7.40 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:18.10        肺:10    膀胱:- 腎臓:8.10 下垂体:25.80 甲状腺:- 副腎:- 膵臓:18.80 乳腺:32.60 唾液腺:-
GeneChip nodata
CAGE 子宮:2.63 胎盤:2.12 前立腺:2.19 卵巣:2.30 精巣:2.05 心臓:- 骨格筋:- 食道:- 胃:1.35 腸:1.55 結腸:2.27     肝臓:2.20    肺:3.08 膀胱:2.31 腎臓:- 下垂体:2.96 甲状腺:- 副腎:2.52 膵臓:1.30 乳腺:2.38 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.47 食道:- 胃:- 腸:- 結腸:-     肝臓:6.40        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_001163775
Gene ID 381921
Unigene ID Mm.259634
Probe set ID -
Ensembl ID ENSMUSG00000059981

オーソログ対応遺伝子

ヒト[4]  NM_004783, NM_016151
ラット[1]  NM_022702, NM_016151

染色体

7F3  [134,009,192  -  134,028,217]

遺伝子ファミリー (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11217851
12466851
12477932
14610273
14621295
15033168
15226823
15489334
15782199
16141072
16141073
16602821
18799693
21267068
22683681
22883308
23382219

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0000186  activation of MAPKK activity
GO:0048041  focal adhesion formation
GO:0031572  G2/M transition DNA damage checkpoint
GO:0016310  phosphorylation
GO:0046330  positive regulation of JNK cascade
GO:0032874  positive regulation of stress-activated MAPK cascade
GO:0006468  protein amino acid phosphorylation
GO:0008360  regulation of cell shape
GO:0006974  response to DNA damage stimulus
GO:0006950  response to stress
GO:0051403  stress-activated MAPK cascade

Cellular Component

GO:0042995  cell projection
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0031410  cytoplasmic vesicle
GO:0005856  cytoskeleton
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0016301  kinase activity
GO:0031434  mitogen-activated protein kinase kinase binding
GO:0000166  nucleotide binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups