histone deacetylase 1

詳細情報を見る

同義遺伝子名

histone deacetylase 1, MGC118085, Hdac1-ps, Histone deacetylase 1, Hdac1, HD1, MGC102534, RPD3

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:6.90 小脳:- 脳幹:- 脳梁:- 松果体:257.80 末梢神経:19.10 脊柱:- 網膜:32.10 目:15.20 動脈:- 静脈:- リンパ節:- 末梢血:28.80 脾臓:- 胸腺:39.50 骨髄:12.80 脂肪:- 骨:37.60 皮膚:23.80
GeneChip 大脳:7.68 小脳:7.49 脳幹:- 脳梁:- 松果体:- 末梢神経:7.90 脊柱:7.57 網膜:8.17 目:8.90 動脈:- 静脈:9.54 リンパ節:10.22 末梢血:- 脾臓:9.98 胸腺:- 骨髄:10.09 脂肪:9.07 骨:10.10 皮膚:9.13
CAGE 大脳:1.56 小脳:- 脳幹:1.79 脳梁:- 松果体:- 末梢神経:- 脊柱:1.38 網膜:- 目:- 動脈:1.62 静脈:- リンパ節:1.98 末梢血:- 脾臓:1.73 胸腺:2.25 骨髄:- 脂肪:- 骨:2.72 皮膚:1.53
RNA-seq 大脳:5.01 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:13.80 前立腺:- 卵巣:- 精巣:36.90 心臓:18.60 骨格筋:35.50 食道:- 胃:- 腸:- 結腸:17.60     肝臓:27.20        肺:30.10    膀胱:- 腎臓:24.20 下垂体:77.50 甲状腺:- 副腎:- 膵臓:18.80 乳腺:49 唾液腺:-
GeneChip 子宮:9.56 胎盤:9.21 前立腺:8.94 卵巣:9.23 精巣:10.30 心臓:7.40 骨格筋:7.86 食道:- 胃:9.71 腸:9.73 結腸:- 肝臓:8.11 肺:9.06 膀胱:9.19 腎臓:8.59 下垂体:9.39 甲状腺:- 副腎:9.36 膵臓:7.48 乳腺:9.10 唾液腺:8.43
CAGE 子宮:1.98 胎盤:1.98 前立腺:1.91 卵巣:2.18 精巣:4.87 心臓:- 骨格筋:- 食道:- 胃:0.67 腸:1.80 結腸:1.96     肝臓:1.80    肺:1.73 膀胱:2.07 腎臓:- 下垂体:2.10 甲状腺:- 副腎:2.02 膵臓:0.84 乳腺:1.83 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:3.47 食道:- 胃:- 腸:- 結腸:-     肝臓:4.63        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_008228
Gene ID 433759
Unigene ID Mm.391033
Probe set ID 1448246_at  [Mouse430_2]
Ensembl ID ENSMUSG00000028800

オーソログ対応遺伝子

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8917507
9139821
9271381
9702189
9823308
10204490
10349636
10357820
10409740
10570134
10615135
10673037
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0034599  cellular response to oxidative stress
GO:0016568  chromatin modification
GO:0042733  embryonic digit morphogenesis
GO:0007492  endoderm development
GO:0009913  epidermal cell differentiation
GO:0060789  hair follicle placode formation
GO:0021766  hippocampus development
GO:0016575  histone deacetylation
GO:0070932  histone H3 deacetylation
GO:0070933  histone H4 deacetylation
GO:0043922  negative regulation by host of viral transcription
GO:0060766  negative regulation of androgen receptor signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0008285  negative regulation of cell proliferation
GO:0043524  negative regulation of neuron apoptosis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0030182  neuron differentiation
GO:0042475  odontogenesis of dentine-containing tooth
GO:0008284  positive regulation of cell proliferation
GO:0048714  positive regulation of oligodendrocyte differentiation
GO:0010870  positive regulation of receptor biosynthetic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006476  protein amino acid deacetylation
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0043025  cell soma
GO:0000785  chromatin
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0000792  heterochromatin
GO:0000118  histone deacetylase complex
GO:0000790  nuclear chromatin
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0016581  NuRD complex
GO:0043234  protein complex
GO:0016580  Sin3 complex
GO:0005667  transcription factor complex
GO:0017053  transcriptional repressor complex

Molecular Function

GO:0003682  chromatin binding
GO:0003677  DNA binding
GO:0019899  enzyme binding
GO:0004407  histone deacetylase activity
GO:0031078  histone deacetylase activity (H3-K14 specific)
GO:0034739  histone deacetylase activity (H3-K16 specific)
GO:0032129  histone deacetylase activity (H3-K9 specific)
GO:0042826  histone deacetylase binding
GO:0016787  hydrolase activity
GO:0032041  NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0046969  NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970  NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0033558  protein deacetylase activity
GO:0033613  transcription activator binding
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity
GO:0008134  transcription factor binding