glycogen synthase kinase 3 beta

詳細情報を見る

同義遺伝子名

GSK-3 beta, glycogen synthase kinase 3 beta, GSK3, GSK-3, Gsk3b, Glycogen synthase kinase-3 beta, 7330414F15Rik, C86142, GSK-3beta, 8430431H08Rik

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:97.20 小脳:147.40 脳幹:127.10 脳梁:- 松果体:- 末梢神経:191.10 脊柱:47.30 網膜:225 目:144.40 動脈:- 静脈:- リンパ節:54 末梢血:28.80 脾臓:52.70 胸腺:345.80 骨髄:25.60 脂肪:425.40 骨:100.20 皮膚:110.80
GeneChip 大脳:9.13 小脳:8.36 脳幹:- 脳梁:- 松果体:- 末梢神経:9.82 脊柱:9.10 網膜:8.36 目:8.18 動脈:- 静脈:7.93 リンパ節:7.50 末梢血:- 脾臓:7.74 胸腺:- 骨髄:8.03 脂肪:8.18 骨:7.83 皮膚:8.33
CAGE 大脳:4.89 小脳:- 脳幹:5.09 脳梁:- 松果体:- 末梢神経:- 脊柱:5.14 網膜:- 目:- 動脈:4.56 静脈:- リンパ節:4.54 末梢血:- 脾臓:4.01 胸腺:4.73 骨髄:- 脂肪:- 骨:4.14 皮膚:4.87
RNA-seq 大脳:4.72 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:27.60 前立腺:123.50 卵巣:34.50 精巣:133 心臓:130.20 骨格筋:35.50 食道:- 胃:- 腸:- 結腸:52.90     肝臓:36.20        肺:90.40    膀胱:66.20 腎臓:56.40 下垂体:25.80 甲状腺:- 副腎:424.40 膵臓:65.70 乳腺:124.10 唾液腺:-
GeneChip 子宮:7.66 胎盤:8.56 前立腺:7.65 卵巣:8.47 精巣:10.21 心臓:8.15 骨格筋:8.75 食道:- 胃:7.68 腸:8.27 結腸:- 肝臓:7.56 肺:8.25 膀胱:7.96 腎臓:7.90 下垂体:8.14 甲状腺:- 副腎:8.33 膵臓:7.71 乳腺:8.06 唾液腺:8.69
CAGE 子宮:4.69 胎盤:4.64 前立腺:4.39 卵巣:4.65 精巣:6.15 心臓:- 骨格筋:- 食道:- 胃:3.51 腸:4.39 結腸:4.29     肝臓:3.90    肺:4.67 膀胱:4.47 腎臓:- 下垂体:4.31 甲状腺:- 副腎:4.31 膵臓:4.06 乳腺:4.22 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:3.34 食道:- 胃:- 腸:- 結腸:-     肝臓:2.31        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_019827
Gene ID 56637
Unigene ID Mm.394930
Probe set ID 1451020_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022812

オーソログ対応遺伝子

ヒト[2]  NM_001146156, NM_002093
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0005975  carbohydrate metabolic process
GO:0030154  cell differentiation
GO:0016477  cell migration
GO:0008283  cell proliferation
GO:0071260  cellular response to mechanical stimulus
GO:0007623  circadian rhythm
GO:0007010  cytoskeleton organization
GO:0001837  epithelial to mesenchymal transition
GO:0006983  ER overload response
GO:0030010  establishment of cell polarity
GO:0007163  establishment or maintenance of cell polarity
GO:0045444  fat cell differentiation
GO:0006349  genetic imprinting
GO:0005977  glycogen metabolic process
GO:0021766  hippocampus development
GO:0044027  hypermethylation of CpG island
GO:0006917  induction of apoptosis
GO:0007275  multicellular organismal development
GO:0007520  myoblast fusion
GO:0014902  myotube differentiation
GO:0043066  negative regulation of apoptosis
GO:0010614  negative regulation of cardiac muscle hypertrophy
GO:0050774  negative regulation of dendrite morphogenesis
GO:0043407  negative regulation of MAP kinase activity
GO:0051534  negative regulation of NFAT protein import into nucleus
GO:0032091  negative regulation of protein binding
GO:0031333  negative regulation of protein complex assembly
GO:0009968  negative regulation of signal transduction
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0007399  nervous system development
GO:0009887  organ morphogenesis
GO:0018105  peptidyl-serine phosphorylation
GO:0016310  phosphorylation
GO:0001954  positive regulation of cell-matrix adhesion
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0010800  positive regulation of peptidyl-threonine phosphorylation
GO:0032092  positive regulation of protein binding
GO:0031334  positive regulation of protein complex assembly
GO:0046827  positive regulation of protein export from nucleus
GO:0032855  positive regulation of Rac GTPase activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006468  protein amino acid phosphorylation
GO:0006611  protein export from nucleus
GO:0000320  re-entry into mitotic cell cycle
GO:0032886  regulation of microtubule-based process
GO:0048168  regulation of neuronal synaptic plasticity
GO:0071109  superior temporal gyrus development
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0030877  beta-catenin destruction complex
GO:0043025  cell soma
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0043198  dendritic shaft
GO:0043197  dendritic spine
GO:0030426  growth cone
GO:0016020  membrane
GO:0045121  membrane raft
GO:0043227  membrane-bounded organelle
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0043234  protein complex
GO:0030529  ribonucleoprotein complex

Molecular Function

GO:0005524  ATP binding
GO:0008013  beta-catenin binding
GO:0005178  integrin binding
GO:0035255  ionotropic glutamate receptor binding
GO:0016301  kinase activity
GO:0051059  NF-kappaB binding
GO:0000166  nucleotide binding
GO:0002039  p53 binding
GO:0005515  protein binding
GO:0034236  protein kinase A catalytic subunit binding
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0004674  protein serine/threonine kinase activity
GO:0048156  tau protein binding
GO:0050321  tau-protein kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0031625  ubiquitin protein ligase binding