mechanistic target of rapamycin (serine/threonine kinase)

同義遺伝子名

Mammalian target of rapamycin, RAPT1, FRAP, Frap1, FKBP12-rapamycin complex-associated protein, AI327068, 2610315D21Rik, mTOR, FRAP2, FKBP-rapamycin-associated protein FRAP, Rapamycin target protein, MGC118056, Frap, RAFT1, flat

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:236.20

小脳:36.80

脳幹:-

脳梁:-

松果体:515.60

末梢神経:76.40

脊柱:-

網膜:192.90

目:98.80

動脈:-

静脈:-

リンパ節:32.40

末梢血:14.40

脾臓:105.30

胸腺:59.30

骨髄:-

脂肪:-

骨:12.50

皮膚:23.80

GeneChip

大脳:6.61

小脳:6.93

脳幹:-

脳梁:-

松果体:-

末梢神経:6.94

脊柱:6.87

網膜:6.64

目:6.81

動脈:-

静脈:6.63

リンパ節:6.80

末梢血:-

脾臓:6.72

胸腺:-

骨髄:7.10

脂肪:7.18

骨:6.77

皮膚:6.60

CAGE

大脳:3.47

小脳:-

脳幹:3.46

脳梁:-

松果体:-

末梢神経:-

脊柱:3.39

網膜:-

目:-

動脈:3.44

静脈:-

リンパ節:2.82

末梢血:-

脾臓:2.66

胸腺:2.89

骨髄:-

脂肪:-

骨:2.29

皮膚:2.54

RNA-seq

大脳:9.13

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:87.20

胎盤:621.30

前立腺:-

卵巣:57.50

精巣:125.60

心臓:18.60

骨格筋:-

食道:-

胃:-

腸:-

結腸:52.90

肝臓:9.10

肺:30.10

膀胱:-

腎臓:145.10

下垂体:-

甲状腺:112.50

副腎:-

膵臓:103.20

乳腺:94.70

唾液腺:162

GeneChip

子宮:6.39

胎盤:6.66

前立腺:6.66

卵巣:6.54

精巣:7.17

心臓:7.21

骨格筋:7.11

食道:-

胃:6.94

腸:6.66

結腸:-

肝臓:7.12

肺:6.50

膀胱:6.61

腎臓:7.52

下垂体:6.79

甲状腺:-

副腎:6.67

膵臓:7.38

乳腺:6.74

唾液腺:6.68

CAGE

子宮:2.47

胎盤:2.73

前立腺:2.52

卵巣:2.78

精巣:4.56

心臓:-

骨格筋:-

食道:-

胃:2.44

腸:2.13

結腸:2.79

肝臓:2.95

肺:2.88

膀胱:2.95

腎臓:-

下垂体:2.81

甲状腺:-

副腎:3.19

膵臓:3.27

乳腺:2.70

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:2.66

食道:-

胃:-

腸:-

結腸:-

肝臓:4.16

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_020009
Gene ID	56717
Unigene ID	Mm.21158
Probe set ID	1436267_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000028991

オーソログ対応遺伝子

ヒト[1]	NM_004958
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000403	Phosphatidylinositol 3-/4-kinase, catalytic
IPR014009	PIK-related kinase
IPR011009	Protein kinase-like domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0016049	cell growth
GO:0030030	cell projection organization
GO:0071456	cellular response to hypoxia
GO:0031669	cellular response to nutrient levels
GO:0007281	germ cell development
GO:0010507	negative regulation of autophagy
GO:0045792	negative regulation of cell size
GO:0016242	negative regulation of macroautophagy
GO:0051534	negative regulation of NFAT protein import into nucleus
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0016310	phosphorylation
GO:0030838	positive regulation of actin filament polymerization
GO:0001938	positive regulation of endothelial cell proliferation
GO:0010628	positive regulation of gene expression
GO:0010592	positive regulation of lamellipodium assembly
GO:0046889	positive regulation of lipid biosynthetic process
GO:0010831	positive regulation of myotube differentiation
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0051897	positive regulation of protein kinase B signaling cascade
GO:0051496	positive regulation of stress fiber formation
GO:0045945	positive regulation of transcription from RNA polymerase III promoter
GO:0045727	positive regulation of translation
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0032956	regulation of actin cytoskeleton organization
GO:0006109	regulation of carbohydrate metabolic process
GO:0043610	regulation of carbohydrate utilization
GO:0031998	regulation of fatty acid beta-oxidation
GO:0005979	regulation of glycogen biosynthetic process
GO:0045859	regulation of protein kinase activity
GO:0032314	regulation of Rac GTPase activity
GO:0032095	regulation of response to food
GO:0043200	response to amino acid stimulus
GO:0032868	response to insulin stimulus
GO:0006950	response to stress
GO:0031529	ruffle organization
GO:0031929	TOR signaling pathway

Cellular Component

GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0030425	dendrite
GO:0012505	endomembrane system
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005764	lysosome
GO:0016020	membrane
GO:0005741	mitochondrial outer membrane
GO:0005739	mitochondrion
GO:0070438	mTOR-FKBP12 complex
GO:0005634	nucleus
GO:0016605	PML body
GO:0031931	TORC1 complex
GO:0031932	TORC2 complex

Molecular Function

GO:0005524	ATP binding
GO:0008144	drug binding
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0051219	phosphoprotein binding
GO:0016773	phosphotransferase activity, alcohol group as acceptor
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0004674	protein serine/threonine kinase activity
GO:0043022	ribosome binding
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

mechanistic target of rapamycin (serine/threonine kinase)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function