PYD and CARD domain containing

詳細情報を見る

同義遺伝子名

Asc, TNS1, TMS-1, PYD and CARD domain containing, masc, Pycard, mASC, 9130417A21Rik, CARD5, PYD and CARD domain-containing protein

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:8.70 小脳:- 脳幹:- 脳梁:- 松果体:1031.20 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:215.70 脾臓:39.50 胸腺:138.30 骨髄:243.60 脂肪:- 骨:125.20 皮膚:118.80
GeneChip 大脳:4.22 小脳:4.26 脳幹:- 脳梁:- 松果体:- 末梢神経:4.28 脊柱:4.48 網膜:4.40 目:5.13 動脈:- 静脈:4.20 リンパ節:4.47 末梢血:- 脾臓:4.69 胸腺:- 骨髄:4.60 脂肪:4.43 骨:4.32 皮膚:5.21
CAGE 大脳:0.69 小脳:- 脳幹:1.32 脳梁:- 松果体:- 末梢神経:- 脊柱:1.63 網膜:- 目:- 動脈:2.03 静脈:- リンパ節:3.77 末梢血:- 脾臓:3.57 胸腺:4.63 骨髄:- 脂肪:- 骨:3.32 皮膚:3.93
RNA-seq 大脳:0.87 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:13.80 前立腺:- 卵巣:- 精巣:14.80 心臓:18.60 骨格筋:- 食道:- 胃:261.80 腸:776.40 結腸:211.50     肝臓:-        肺:40.20    膀胱:- 腎臓:16.10 下垂体:- 甲状腺:- 副腎:- 膵臓:37.50 乳腺:29.40 唾液腺:108
GeneChip 子宮:4.49 胎盤:4.30 前立腺:4.59 卵巣:4.15 精巣:4.57 心臓:4.50 骨格筋:4.61 食道:- 胃:4.90 腸:6.33 結腸:- 肝臓:4.75 肺:4.36 膀胱:4.22 腎臓:4.66 下垂体:4.36 甲状腺:- 副腎:4.30 膵臓:4.50 乳腺:4.43 唾液腺:4.99
CAGE 子宮:3.73 胎盤:1.33 前立腺:2.74 卵巣:2.35 精巣:1.18 心臓:- 骨格筋:- 食道:- 胃:4.13 腸:4.57 結腸:5.30     肝臓:1.30    肺:3.02 膀胱:3.14 腎臓:- 下垂体:1.48 甲状腺:- 副腎:2.22 膵臓:2.97 乳腺:3.52 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.43 食道:- 胃:- 腸:- 結腸:-     肝臓:1.81        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_023258
Gene ID 66824
Unigene ID Mm.24163
Probe set ID 1417347_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030793

オーソログ対応遺伝子

ヒト[3]  NM_013258, NM_145182, NM_152901
ラット[1]  NM_172322, NM_145182, NM_152901

染色体

-

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11139337
11217851
11250163
12466851
12477932
12819136
14610273
15190255
15489334
15507117
15604097
16141072
16141073
16183747
16230474
16407888
16407889
16407890
16444259
16546100
16547271
16585594
16602821
16648853
16717117
17008311
17403772
17433728
17452523
17599094
17641058
17878377
17935074
17982084
17992263
18070936
18288107
18490757
18496530
18511561
18541743
18554416
18566365
18624356
18768827
18799693
19006696
19064716
19139171
19158675
19158679
19164858
19218193
19237518
19339971
19342685
19362020
19364881
19501000
19542372
19570822
19576795
19587006
19596994
19652710
19662634
19684085
19696895
19717510
19717512
19783673
19915568
19918053
20007575
20007584
20036165
20177071
20194588
20200276
20226691
20333626
20348425
20351692
20368281
20383149
20385749
20393137
20393140
20428172
20457908
20495560
20566831
20603313
20610651
20668698
20722078
20802146
20808838
20855874
20947763
20962258
20974980
21037094
21057511
21059855
21059925
21124315
21267068
21270336
21278344
21282498
21331573
21349431
21396389
21464320
21474346
21478880
21487011
21497116
21508263
21533069
21565393
21600797
21602824
21622869
21646297
21681738
21687424
21718313
21731762
21746921
21771913
21777570
21812013
21856950
21862613
21892172
21902795
21918512
21957143
22002608
22003197
22046355
22058415
22101787
22106299
22109549
22174673
22213227
22241982
22286270
22297845
22308317
22323544
22331066
22342844
22361326
22365665
22426419
22440612
22444631
22464733
22474394
22541070
22555457
22647887
22699511
22723924
22733741
22840842
22848390
22888139
22905357
22911706
22945633
22981536
23064150
23064768
23071280
23071286
23075849
23090995
23115038
23209417
23219391
23221343
23264657
23267025
23297192
23297415
23302887
23307811
23308247
23348507
23408710
23427254
23455376
23460746
23468973
23502856
23509366
23529619
23582325
23625200
23630357
23644505
23696660
23809161
23817414
23818043
23942123
23964013
23966627
23975862
23997220
24093676
24157462
24164497
24185614
24248350
24388751
24395802
24412611
24478101
24484406
24489101
24508291
24606881
24631027
24696236

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006919  activation of caspase activity
GO:0002218  activation of innate immune response
GO:0006915  apoptosis
GO:0071347  cellular response to interleukin-1
GO:0071222  cellular response to lipopolysaccharide
GO:0071356  cellular response to tumor necrosis factor
GO:0050829  defense response to Gram-negative bacterium
GO:0051607  defense response to virus
GO:0042771  DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis
GO:0006917  induction of apoptosis
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0032611  interleukin-1 beta production
GO:0001773  myeloid dendritic cell activation
GO:0002277  myeloid dendritic cell activation during immune response
GO:0043124  negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032688  negative regulation of interferon-beta production
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0030838  positive regulation of actin filament polymerization
GO:0042104  positive regulation of activated T cell proliferation
GO:0002821  positive regulation of adaptive immune response
GO:0002588  positive regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0043065  positive regulation of apoptosis
GO:0043280  positive regulation of caspase activity
GO:0090197  positive regulation of chemokine secretion
GO:0002230  positive regulation of defense response to virus by host
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0032729  positive regulation of interferon-gamma production
GO:0050718  positive regulation of interleukin-1 beta secretion
GO:0032755  positive regulation of interleukin-6 production
GO:0046330  positive regulation of JNK cascade
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0050766  positive regulation of phagocytosis
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0050870  positive regulation of T cell activation
GO:0051091  positive regulation of transcription factor activity
GO:0032760  positive regulation of tumor necrosis factor production
GO:0006508  proteolysis
GO:0042981  regulation of apoptosis
GO:0043281  regulation of caspase activity
GO:0031647  regulation of protein stability
GO:0032314  regulation of Rac GTPase activity
GO:0010803  regulation of tumor necrosis factor-mediated signaling pathway
GO:0033209  tumor necrosis factor-mediated signaling pathway

Cellular Component

GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005783  endoplasmic reticulum
GO:0005576  extracellular region
GO:0008385  IkappaB kinase complex
GO:0005622  intracellular
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0043234  protein complex

Molecular Function

GO:0016505  apoptotic protease activator activity
GO:0004197  cysteine-type endopeptidase activity
GO:0002020  protease binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0032090  Pyrin domain binding