disabled homolog 2 (Drosophila) interacting protein

詳細情報を見る

同義遺伝子名

DAB2-interacting protein, 2310011D08Rik, AI480459, Dab2ip, Kiaa1743, KIAA1743, mKIAA1743, MGC144147, Disabled homolog 2-interacting protein

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:222.30 小脳:55.30 脳幹:158.90 脳梁:- 松果体:- 末梢神経:38.20 脊柱:94.60 網膜:64.30 目:98.80 動脈:- 静脈:- リンパ節:32.40 末梢血:14.40 脾臓:- 胸腺:39.50 骨髄:25.60 脂肪:212.70 骨:125.20 皮膚:118.80
GeneChip 大脳:8.42 小脳:10.12 脳幹:- 脳梁:- 松果体:- 末梢神経:8.66 脊柱:8.46 網膜:8.31 目:7.77 動脈:- 静脈:8.26 リンパ節:7.04 末梢血:- 脾臓:7.46 胸腺:- 骨髄:6.83 脂肪:8.26 骨:7.18 皮膚:8.45
CAGE 大脳:4.24 小脳:- 脳幹:3.30 脳梁:- 松果体:- 末梢神経:- 脊柱:3.05 網膜:- 目:- 動脈:3.40 静脈:- リンパ節:1.64 末梢血:- 脾臓:2.10 胸腺:2.22 骨髄:- 脂肪:- 骨:2.59 皮膚:3.22
RNA-seq 大脳:12.73 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:82.80 前立腺:30.90 卵巣:34.50 精巣:22.20 心臓:55.80 骨格筋:284.10 食道:- 胃:32.70 腸:37 結腸:35.20     肝臓:54.30        肺:120.50    膀胱:66.20 腎臓:72.50 下垂体:129.20 甲状腺:- 副腎:- 膵臓:37.50 乳腺:58.80 唾液腺:108
GeneChip 子宮:8.72 胎盤:8.22 前立腺:8.09 卵巣:8.34 精巣:7.71 心臓:8.90 骨格筋:8.99 食道:- 胃:8.50 腸:9.06 結腸:- 肝臓:6.70 肺:9 膀胱:8.90 腎臓:8.03 下垂体:8.81 甲状腺:- 副腎:8.53 膵臓:7.68 乳腺:8.27 唾液腺:9.18
CAGE 子宮:3.69 胎盤:3.16 前立腺:2.90 卵巣:3.13 精巣:1.80 心臓:- 骨格筋:- 食道:- 胃:3.25 腸:4.01 結腸:4.19     肝臓:2.62    肺:4.03 膀胱:3.90 腎臓:- 下垂体:3.47 甲状腺:- 副腎:3.26 膵臓:2.56 乳腺:3.50 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:3.25 食道:- 胃:- 腸:- 結腸:-     肝臓:1.85        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007257  activation of JUN kinase activity
GO:0000185  activation of MAPKKK activity
GO:0001525  angiogenesis
GO:0006915  apoptosis
GO:0070059  apoptosis in response to endoplasmic reticulum stress
GO:0007049  cell cycle
GO:0021814  cell motility involved in cerebral cortex radial glia guided migration
GO:0044257  cellular protein catabolic process
GO:0071364  cellular response to epidermal growth factor stimulus
GO:0071347  cellular response to interleukin-1
GO:0071222  cellular response to lipopolysaccharide
GO:0071356  cellular response to tumor necrosis factor
GO:0007252  I-kappaB phosphorylation
GO:0008625  induction of apoptosis via death domain receptors
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0021819  layer formation in the cerebral cortex
GO:0007275  multicellular organismal development
GO:0016525  negative regulation of angiogenesis
GO:0030308  negative regulation of cell growth
GO:0008285  negative regulation of cell proliferation
GO:0010596  negative regulation of endothelial cell migration
GO:0042059  negative regulation of epidermal growth factor receptor signaling pathway
GO:0010633  negative regulation of epithelial cell migration
GO:0050680  negative regulation of epithelial cell proliferation
GO:0010719  negative regulation of epithelial to mesenchymal transition
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0048147  negative regulation of fibroblast proliferation
GO:0070317  negative regulation of G0 to G1 transition
GO:0034260  negative regulation of GTPase activity
GO:0043124  negative regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043407  negative regulation of MAP kinase activity
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0043553  negative regulation of phosphoinositide 3-kinase activity
GO:0014067  negative regulation of phosphoinositide 3-kinase cascade
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0034261  negative regulation of Ras GTPase activity
GO:0046580  negative regulation of Ras protein signal transduction
GO:0034144  negative regulation of toll-like receptor 4 signaling pathway
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030948  negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0048812  neuron projection morphogenesis
GO:0043065  positive regulation of apoptosis
GO:0071158  positive regulation of cell cycle arrest
GO:0046330  positive regulation of JNK cascade
GO:0043507  positive regulation of JUN kinase activity
GO:0043410  positive regulation of MAPKKK cascade
GO:0010976  positive regulation of neuron projection development
GO:0045732  positive regulation of protein catabolic process
GO:0032320  positive regulation of Ras GTPase activity
GO:0090129  positive regulation of synapse maturation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032312  regulation of ARF GTPase activity
GO:0040008  regulation of growth
GO:0043122  regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043254  regulation of protein complex assembly
GO:0051056  regulation of small GTPase mediated signal transduction
GO:0006950  response to stress
GO:0006986  response to unfolded protein
GO:0007165  signal transduction
GO:0035148  tube lumen formation

Cellular Component

GO:0030424  axon
GO:0042995  cell projection
GO:0043025  cell soma
GO:0032809  cell soma membrane
GO:0005737  cytoplasm
GO:0030139  endocytic vesicle
GO:0005622  intracellular
GO:0031235  intrinsic to internal side of plasma membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005123  death receptor binding
GO:0005096  GTPase activator activity
GO:0042802  identical protein binding
GO:0019900  kinase binding
GO:0031434  mitogen-activated protein kinase kinase binding
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0032266  phosphatidylinositol 3-phosphate binding
GO:0070273  phosphatidylinositol-4-phosphate binding
GO:0043548  phosphoinositide 3-kinase binding
GO:0005543  phospholipid binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0042803  protein homodimerization activity
GO:0019901  protein kinase binding
GO:0047485  protein N-terminus binding
GO:0051721  protein phosphatase 2A binding
GO:0005099  Ras GTPase activator activity
GO:0017124  SH3 domain binding
GO:0043184  vascular endothelial growth factor receptor 2 binding