interleukin-1 receptor-associated kinase 3

詳細情報を見る

同義遺伝子名

IRAK-3, 4833428C18Rik, interleukin-1 receptor-associated kinase 3, AI563835, Irak3, IRAK-M, Interleukin-1 receptor-associated kinase 3, IL-1 receptor-associated kinase M

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:3.50 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:168.80 静脈:- リンパ節:- 末梢血:158.10 脾臓:- 胸腺:9.90 骨髄:115.40 脂肪:- 骨:12.50 皮膚:55.40
GeneChip nodata
CAGE 大脳:0.72 小脳:- 脳幹:1.25 脳梁:- 松果体:- 末梢神経:- 脊柱:1.33 網膜:- 目:- 動脈:3.20 静脈:- リンパ節:4.25 末梢血:- 脾臓:2.99 胸腺:1.06 骨髄:- 脂肪:- 骨:3.57 皮膚:3.46
RNA-seq 大脳:0.93 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:130.90 胎盤:- 前立腺:30.90 卵巣:11.50 精巣:59.10 心臓:37.20 骨格筋:71 食道:- 胃:- 腸:- 結腸:-     肝臓:9.10        肺:-    膀胱:- 腎臓:8.10 下垂体:- 甲状腺:- 副腎:- 膵臓:28.10 乳腺:16.30 唾液腺:162
GeneChip nodata
CAGE 子宮:2.24 胎盤:2.22 前立腺:2.51 卵巣:1.74 精巣:0.75 心臓:- 骨格筋:- 食道:- 胃:1.35 腸:1.22 結腸:1.72     肝臓:1.52    肺:2.78 膀胱:2.37 腎臓:- 下垂体:1.31 甲状腺:- 副腎:1.82 膵臓:2.45 乳腺:2.03 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.70 食道:- 胃:- 腸:- 結腸:-     肝臓:1.68        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0019221  cytokine-mediated signaling pathway
GO:0070498  interleukin-1-mediated signaling pathway
GO:0001960  negative regulation of cytokine-mediated signaling pathway
GO:0045824  negative regulation of innate immune response
GO:0032695  negative regulation of interleukin-12 production
GO:0032715  negative regulation of interleukin-6 production
GO:0010936  negative regulation of macrophage cytokine production
GO:0043407  negative regulation of MAP kinase activity
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0042177  negative regulation of protein catabolic process
GO:0043242  negative regulation of protein complex disassembly
GO:0034122  negative regulation of toll-like receptor signaling pathway
GO:0032720  negative regulation of tumor necrosis factor production
GO:0016310  phosphorylation
GO:0010933  positive regulation of macrophage tolerance induction
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0042981  regulation of apoptosis
GO:0043244  regulation of protein complex disassembly
GO:0043330  response to exogenous dsRNA
GO:0070555  response to interleukin-1
GO:0032496  response to lipopolysaccharide
GO:0032494  response to peptidoglycan
GO:0009615  response to virus
GO:0007165  signal transduction

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0016301  kinase activity
GO:0000287  magnesium ion binding
GO:0000166  nucleotide binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups