interleukin-1 receptor-associated kinase 3

同義遺伝子名

IRAK-3, 4833428C18Rik, interleukin-1 receptor-associated kinase 3, AI563835, Irak3, IRAK-M, Interleukin-1 receptor-associated kinase 3, IL-1 receptor-associated kinase M

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:3.50

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:168.80

静脈:-

リンパ節:-

末梢血:158.10

脾臓:-

胸腺:9.90

骨髄:115.40

脂肪:-

骨:12.50

皮膚:55.40

GeneChip

nodata

CAGE

大脳:0.72

小脳:-

脳幹:1.25

脳梁:-

松果体:-

末梢神経:-

脊柱:1.33

網膜:-

目:-

動脈:3.20

静脈:-

リンパ節:4.25

末梢血:-

脾臓:2.99

胸腺:1.06

骨髄:-

脂肪:-

骨:3.57

皮膚:3.46

RNA-seq

大脳:0.93

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:130.90

胎盤:-

前立腺:30.90

卵巣:11.50

精巣:59.10

心臓:37.20

骨格筋:71

食道:-

胃:-

腸:-

結腸:-

肝臓:9.10

肺:-

膀胱:-

腎臓:8.10

下垂体:-

甲状腺:-

副腎:-

膵臓:28.10

乳腺:16.30

唾液腺:162

GeneChip

nodata

CAGE

子宮:2.24

胎盤:2.22

前立腺:2.51

卵巣:1.74

精巣:0.75

心臓:-

骨格筋:-

食道:-

胃:1.35

腸:1.22

結腸:1.72

肝臓:1.52

肺:2.78

膀胱:2.37

腎臓:-

下垂体:1.31

甲状腺:-

副腎:1.82

膵臓:2.45

乳腺:2.03

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:1.70

食道:-

胃:-

腸:-

結腸:-

肝臓:1.68

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_028679
Gene ID	73914
Unigene ID	Mm.146194
Probe set ID	-
Ensembl ID	ENSMUSG00000020227

オーソログ対応遺伝子

ヒト[4]	NM_001142523, NM_007199
ラット[1]	NM_001108101, NM_007199

染色体

10D2 [119,578,704 - 119,639,186]

近くの遺伝子を探す
- -5kb から +5kb の範囲
- -10kb から +10kb の範囲

遺伝子ファミリー (Interpro ID)

IPR000488	Death
IPR011029	DEATH-like
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0019221	cytokine-mediated signaling pathway
GO:0070498	interleukin-1-mediated signaling pathway
GO:0001960	negative regulation of cytokine-mediated signaling pathway
GO:0045824	negative regulation of innate immune response
GO:0032695	negative regulation of interleukin-12 production
GO:0032715	negative regulation of interleukin-6 production
GO:0010936	negative regulation of macrophage cytokine production
GO:0043407	negative regulation of MAP kinase activity
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0042177	negative regulation of protein catabolic process
GO:0043242	negative regulation of protein complex disassembly
GO:0034122	negative regulation of toll-like receptor signaling pathway
GO:0032720	negative regulation of tumor necrosis factor production
GO:0016310	phosphorylation
GO:0010933	positive regulation of macrophage tolerance induction
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0042981	regulation of apoptosis
GO:0043244	regulation of protein complex disassembly
GO:0043330	response to exogenous dsRNA
GO:0070555	response to interleukin-1
GO:0032496	response to lipopolysaccharide
GO:0032494	response to peptidoglycan
GO:0009615	response to virus
GO:0007165	signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0005634	nucleus

Molecular Function

GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0000287	magnesium ion binding
GO:0000166	nucleotide binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

interleukin-1 receptor-associated kinase 3

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function