amyotrophic lateral sclerosis 2 (juvenile) homolog (human)

 詳細情報を見る

同義遺伝子名

Als2cr6, 9430073A21Rik, Amyotrophic lateral sclerosis protein 2 homolog, MGC27807, 3222402C23Rik, Als2, mKIAA1563, Alsin

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST nodata
GeneChip nodata
CAGE 大脳:3.69 小脳:- 脳幹:2.43 脳梁:- 松果体:- 末梢神経:- 脊柱:2.54 網膜:- 目:- 動脈:2.19 静脈:- リンパ節:2.08 末梢血:- 脾臓:1.63 胸腺:2.80 骨髄:- 脂肪:- 骨:2.09 皮膚:2.37
RNA-seq 大脳:4.08 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST nodata
GeneChip nodata
CAGE 子宮:1.95 胎盤:2.60 前立腺:1.41 卵巣:1.94 精巣:0.99 心臓:- 骨格筋:- 食道:- 胃:1.57 腸:2.67 結腸:3.12     肝臓:3.82    肺:1.76 膀胱:1.80 腎臓:- 下垂体:1.96 甲状腺:- 副腎:2.04 膵臓:1.84 乳腺:2.15 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:7.68 食道:- 胃:- 腸:- 結腸:-     肝臓:5.04        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_146109
Gene ID 74018
Unigene ID -
Probe set ID -
Ensembl ID ENSMUSG00000026024

オーソログ対応遺伝子

ヒト[4]  NM_001135745, NM_020919
ラット[1]  NM_001013413, NM_020919

染色体

1C1.3  [59,219,770  -  59,294,075]

遺伝子ファミリー (Interpro ID)

IPR003123  Vacuolar sorting protein 9

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11217851
11544199
11586298
12466851
12477932
12520002
12693553
12787792
14610273
14691545
15033976
15489334
15579468
16085057
16107644
16141072
16141073
16240357
16321985
16602821
16769894
16802286
16802292
16973244
17015433
17093100
17156857
17239822
17409386
17855450
17955197
18358238
18558633
18799693
19304783
19563800
19630956
20339559
20558214
21267068
21677750
21907703
21937428
22438926
22982304

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0001662  behavioral fear response
GO:0008219  cell death
GO:0007032  endosome organization
GO:0016197  endosome transport
GO:0007626  locomotory behavior
GO:0007041  lysosomal transport
GO:0007528  neuromuscular junction development
GO:0048812  neuron projection morphogenesis
GO:0045860  positive regulation of protein kinase activity
GO:0032855  positive regulation of Rac GTPase activity
GO:0051260  protein homooligomerization
GO:0008104  protein localization
GO:0016601  Rac protein signal transduction
GO:0001881  receptor recycling
GO:0032313  regulation of Rab GTPase activity
GO:0035023  regulation of Rho protein signal transduction
GO:0006979  response to oxidative stress
GO:0035249  synaptic transmission, glutamatergic
GO:0016050  vesicle organization

Cellular Component

GO:0030424  axon
GO:0043025  cell soma
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030425  dendrite
GO:0043197  dendritic spine
GO:0005769  early endosome
GO:0030426  growth cone
GO:0043231  intracellular membrane-bounded organelle
GO:0030027  lamellipodium
GO:0016020  membrane
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0014069  postsynaptic density
GO:0043234  protein complex
GO:0001726  ruffle
GO:0031982  vesicle

Molecular Function

GO:0005085  guanyl-nucleotide exchange factor activity
GO:0042802  identical protein binding
GO:0005543  phospholipid binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0043539  protein serine/threonine kinase activator activity
GO:0005097  Rab GTPase activator activity
GO:0017137  Rab GTPase binding
GO:0017112  Rab guanyl-nucleotide exchange factor activity
GO:0030675  Rac GTPase activator activity
GO:0048365  Rac GTPase binding
GO:0030676  Rac guanyl-nucleotide exchange factor activity
GO:0005089  Rho guanyl-nucleotide exchange factor activity