amyotrophic lateral sclerosis 2 (juvenile) homolog (human)

詳細情報を見る

同義遺伝子名

Als2cr6, 9430073A21Rik, Amyotrophic lateral sclerosis protein 2 homolog, MGC27807, 3222402C23Rik, Als2, mKIAA1563, Alsin

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:99 小脳:73.70 脳幹:63.60 脳梁:- 松果体:- 末梢神経:114.70 脊柱:- 網膜:32.10 目:114 動脈:- 静脈:- リンパ節:140.40 末梢血:100.60 脾臓:105.30 胸腺:69.20 骨髄:12.80 脂肪:- 骨:- 皮膚:31.70
GeneChip nodata
CAGE 大脳:3.69 小脳:- 脳幹:2.43 脳梁:- 松果体:- 末梢神経:- 脊柱:2.54 網膜:- 目:- 動脈:2.19 静脈:- リンパ節:2.08 末梢血:- 脾臓:1.63 胸腺:2.80 骨髄:- 脂肪:- 骨:2.09 皮膚:2.37
RNA-seq 大脳:4.08 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:43.60 胎盤:110.50 前立腺:30.90 卵巣:34.50 精巣:59.10 心臓:18.60 骨格筋:35.50 食道:- 胃:- 腸:- 結腸:-     肝臓:63.40        肺:40.20    膀胱:66.20 腎臓:8.10 下垂体:51.70 甲状腺:- 副腎:424.40 膵臓:112.60 乳腺:45.70 唾液腺:-
GeneChip nodata
CAGE 子宮:1.95 胎盤:2.60 前立腺:1.41 卵巣:1.94 精巣:0.99 心臓:- 骨格筋:- 食道:- 胃:1.57 腸:2.67 結腸:3.12     肝臓:3.82    肺:1.76 膀胱:1.80 腎臓:- 下垂体:1.96 甲状腺:- 副腎:2.04 膵臓:1.84 乳腺:2.15 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:7.68 食道:- 胃:- 腸:- 結腸:-     肝臓:5.04        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0001662  behavioral fear response
GO:0008219  cell death
GO:0007032  endosome organization
GO:0016197  endosome transport
GO:0007626  locomotory behavior
GO:0007041  lysosomal transport
GO:0007528  neuromuscular junction development
GO:0048812  neuron projection morphogenesis
GO:0045860  positive regulation of protein kinase activity
GO:0032855  positive regulation of Rac GTPase activity
GO:0051260  protein homooligomerization
GO:0008104  protein localization
GO:0016601  Rac protein signal transduction
GO:0001881  receptor recycling
GO:0032313  regulation of Rab GTPase activity
GO:0035023  regulation of Rho protein signal transduction
GO:0006979  response to oxidative stress
GO:0035249  synaptic transmission, glutamatergic
GO:0016050  vesicle organization

Cellular Component

GO:0030424  axon
GO:0043025  cell soma
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030425  dendrite
GO:0043197  dendritic spine
GO:0005769  early endosome
GO:0030426  growth cone
GO:0043231  intracellular membrane-bounded organelle
GO:0030027  lamellipodium
GO:0016020  membrane
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0014069  postsynaptic density
GO:0043234  protein complex
GO:0001726  ruffle
GO:0031982  vesicle

Molecular Function

GO:0005085  guanyl-nucleotide exchange factor activity
GO:0042802  identical protein binding
GO:0005543  phospholipid binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0043539  protein serine/threonine kinase activator activity
GO:0005097  Rab GTPase activator activity
GO:0017137  Rab GTPase binding
GO:0017112  Rab guanyl-nucleotide exchange factor activity
GO:0030675  Rac GTPase activator activity
GO:0048365  Rac GTPase binding
GO:0030676  Rac guanyl-nucleotide exchange factor activity
GO:0005089  Rho guanyl-nucleotide exchange factor activity