lysine (K)-specific demethylase 1A

同義遺伝子名

Lsd1, D4Ertd478e, BRAF35-HDAC complex protein BHC110, mKIAA0601, 1810043O07Rik, amine oxidase (flavin containing) domain 2, AA408884, Lysine-specific histone demethylase 1, Kiaa0601, Aof2

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

nodata

GeneChip

大脳:9.10

小脳:8.85

脳幹:-

脳梁:-

松果体:-

末梢神経:9.06

脊柱:8.44

網膜:8.74

目:8.98

動脈:-

静脈:9.58

リンパ節:9.41

末梢血:-

脾臓:9.08

胸腺:-

骨髄:9.11

脂肪:8.53

骨:8.98

皮膚:9.04

CAGE

大脳:3.59

小脳:-

脳幹:3.48

脳梁:-

松果体:-

末梢神経:-

脊柱:3.36

網膜:-

目:-

動脈:2.88

静脈:-

リンパ節:3.21

末梢血:-

脾臓:3.17

胸腺:3.64

骨髄:-

脂肪:-

骨:3.21

皮膚:3.93

RNA-seq

大脳:7.05

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

nodata

GeneChip

子宮:9.71

胎盤:9.86

前立腺:9.53

卵巣:9.56

精巣:9.99

心臓:8.44

骨格筋:8.73

食道:-

胃:8.68

腸:8.93

結腸:-

肝臓:7.65

肺:8.91

膀胱:8.78

腎臓:7.82

下垂体:9.45

甲状腺:-

副腎:8.88

膵臓:8.42

乳腺:9.11

唾液腺:8.89

CAGE

子宮:3.59

胎盤:3.61

前立腺:3.21

卵巣:3.59

精巣:5.13

心臓:-

骨格筋:-

食道:-

胃:3.05

腸:2.65

結腸:3.04

肝臓:2.62

肺:3.26

膀胱:3.37

腎臓:-

下垂体:3.80

甲状腺:-

副腎:3.09

膵臓:3.49

乳腺:3.31

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:3.65

食道:-

胃:-

腸:-

結腸:-

肝臓:2.43

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_133872
Gene ID	99982
Unigene ID	-
Probe set ID	1426762_s_at [Mouse430_2]
Ensembl ID	ENSMUSG00000036940

オーソログ対応遺伝子

ヒト[4]	NM_001009999, NM_015013
ラット[1]	NM_001130098, NM_015013

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

GO:0008283	cell proliferation
GO:0016568	chromatin modification
GO:0034401	chromatin organization during transcription
GO:0030851	granulocyte differentiation
GO:0034720	histone H3-K4 demethylation
GO:0033169	histone H3-K9 demethylation
GO:0001701	in utero embryonic development
GO:0007275	multicellular organismal development
GO:0055001	muscle cell development
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0051572	negative regulation of histone H3-K4 methylation
GO:0051573	negative regulation of histone H3-K9 methylation
GO:0032091	negative regulation of protein binding
GO:0043433	negative regulation of transcription factor activity
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0055114	oxidation reduction
GO:0021983	pituitary gland development
GO:0045648	positive regulation of erythrocyte differentiation
GO:0046886	positive regulation of hormone biosynthetic process
GO:0045654	positive regulation of megakaryocyte differentiation
GO:0051091	positive regulation of transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0006482	protein amino acid demethylation
GO:0010725	regulation of primitive erythrocyte differentiation
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-dependent
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0050681	androgen receptor binding
GO:0003682	chromatin binding
GO:0032451	demethylase activity
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0019899	enzyme binding
GO:0050660	FAD binding
GO:0032452	histone demethylase activity
GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)
GO:0032453	histone demethylase activity (H3-K4 specific)
GO:0032454	histone demethylase activity (H3-K9 specific)
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0043426	MRF binding
GO:0016491	oxidoreductase activity
GO:0002039	p53 binding
GO:0005515	protein binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

lysine (K)-specific demethylase 1A

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function