fms-related tyrosine kinase 4

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:78 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:79.60 前立腺:- 卵巣:- 精巣:- 心臓:19.40 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:-        肺:50.70    膀胱:- 腎臓:63.80 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_053652
Gene ID 114110
Unigene ID Rn.81043
Probe set ID -
Ensembl ID ENSRNOG00000002511

オーソログ対応遺伝子

ヒト[2]  NM_002020, NM_182925
マウス[2]  NM_008029, NM_182925

染色体

10q22  [35,071,002  -  35,112,006]

遺伝子ファミリー (Interpro ID)

IPR000565  DNA topoisomerase, type IIA, subunit B
IPR013106  Immunoglobulin V-set
IPR003596  Immunoglobulin V-set, subgroup
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR020685  Tyrosine-protein kinase
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020933  Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain
IPR009134  Tyrosine-protein kinase, vascular endothelial growth factor receptor (VEGFR), N-terminal
IPR009135  Tyrosine-protein kinase, vascular endothelial growth factor receptor 1 (VEGFR1), N-terminal
IPR009136  Tyrosine-protein kinase, vascular endothelial growth factor receptor 2 (VEGFR2)
IPR009137  Tyrosine-protein kinase, vascular endothelial growth factor receptor 3 (VEGFR3), N-terminal

Link to Pubmed  (Pubmed ID)

7898938
10878616
11683876
15563310
17584927
19196316
19901262
19963036
20127810
20572782
20692049
21072582
21703344
21865112
22170007
22771250
22818386
22959907
22983493
24379135

遺伝子オントロジー  (GO ID)

Biological Process

GO:0048514  blood vessel morphogenesis
GO:0001945  lymph vessel development
GO:0001946  lymphangiogenesis
GO:0043066  negative regulation of apoptosis
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0030307  positive regulation of cell growth
GO:0008284  positive regulation of cell proliferation
GO:0010595  positive regulation of endothelial cell migration
GO:0001938  positive regulation of endothelial cell proliferation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0046330  positive regulation of JNK cascade
GO:0043410  positive regulation of MAPKKK cascade
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0090037  positive regulation of protein kinase C signaling cascade
GO:0010575  positive regulation vascular endothelial growth factor production
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0060312  regulation of blood vessel remodeling
GO:0002040  sprouting angiogenesis
GO:0048010  vascular endothelial growth factor receptor signaling pathway
GO:0001944  vasculature development

Cellular Component

GO:0005737  cytoplasm
GO:0005887  integral to plasma membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0019838  growth factor binding
GO:0019903  protein phosphatase binding
GO:0004714  transmembrane receptor protein tyrosine kinase activity
GO:0005021  vascular endothelial growth factor receptor activity