phosphatidylinositol 3-kinase, catalytic, alpha polypeptide

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:203.40 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:36.90 脊柱:- 網膜:- 目:71.10 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:122.90 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:39.80 前立腺:75.90 卵巣:228.20 精巣:- 心臓:- 骨格筋:265.70 食道:- 胃:- 腸:104.70 結腸:579.70     肝臓:13.30        肺:202.60    膀胱:- 腎臓:- 下垂体:118.40 甲状腺:- 副腎:- 膵臓:113.80 乳腺:- 唾液腺:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID XM_001059407
Gene ID 170911
Unigene ID Rn.44193
Probe set ID -
Ensembl ID -

オーソログ対応遺伝子

ヒト [0]  
マウス [0]  

染色体

2q25  [118,640,274  -  118,669,229]

遺伝子ファミリー (Interpro ID)

IPR016024  Armadillo-type fold
IPR008973  C2 calcium/lipid-binding domain, CaLB
IPR000403  Phosphatidylinositol 3-/4-kinase, catalytic
IPR001263  Phosphoinositide 3-kinase, accessory (PIK) domain
IPR002420  Phosphoinositide 3-kinase, C2
IPR011009  Protein kinase-like domain

Link to Pubmed  (Pubmed ID)

8889548
10860857
11596118
12220227
12477932
12874030
12882977
16847462
17575153
17641274
18955974
19078924
19202327
20514400
20622004
20951313
21127054
21277552
21736902
23759327
24006492

遺伝子オントロジー  (GO ID)

Biological Process

GO:0006006  glucose metabolic process
GO:0044029  hypomethylation of CpG island
GO:0043524  negative regulation of neuron apoptosis
GO:0046854  phosphoinositide phosphorylation
GO:0048015  phosphoinositide-mediated signaling
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0043491  protein kinase B signaling cascade
GO:0040014  regulation of multicellular organism growth

Cellular Component

GO:0005943  1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex
GO:0030027  lamellipodium
GO:0005942  phosphoinositide 3-kinase complex
GO:0005886  plasma membrane

Molecular Function

GO:0016303  1-phosphatidylinositol-3-kinase activity
GO:0005524  ATP binding
GO:0043560  insulin receptor substrate binding
GO:0046934  phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0035005  phosphatidylinositol-4-phosphate 3-kinase activity
GO:0030295  protein kinase activator activity