eukaryotic translation initiation factor 2 alpha kinase 1

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:95.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:73.70 脊柱:- 網膜:- 目:142.20 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:78 胸腺:245.80 骨髄:- 脂肪:- 骨:156.20 皮膚:-
GeneChip nodata
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:79.60 前立腺:38 卵巣:114.10 精巣:82.30 心臓:19.40 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:39.90        肺:202.60    膀胱:- 腎臓:- 下垂体:59.20 甲状腺:- 副腎:- 膵臓:170.70 乳腺:- 唾液腺:-
GeneChip nodata
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_013223
Gene ID 27137
Unigene ID Rn.3333
Probe set ID -
Ensembl ID ENSRNOG00000001050

オーソログ対応遺伝子

ヒト[4]  NM_001134335, NM_014413
マウス[4]  NM_013557, NM_014413

染色体

12p11  [11,039,150  -  11,072,741]

遺伝子ファミリー (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

7908290
12477932
20071449

遺伝子オントロジー  (GO ID)

Biological Process

GO:0008285  negative regulation of cell proliferation
GO:0046986  negative regulation of hemoglobin biosynthetic process
GO:0045947  negative regulation of translational initiation
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0046501  protoporphyrinogen IX metabolic process
GO:0010999  regulation of eIF2 alpha phosphorylation by heme
GO:0046984  regulation of hemoglobin biosynthetic process
GO:0006417  regulation of translation
GO:0009605  response to external stimulus
GO:0006950  response to stress
GO:0006413  translational initiation

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0005524  ATP binding
GO:0004694  eukaryotic translation initiation factor 2alpha kinase activity
GO:0020037  heme binding
GO:0042803  protein homodimerization activity
GO:0004672  protein kinase activity